627 research outputs found
Robustness of a local Fermi Liquid against Ferromagnetism and Phase Separation
We study the properties of Fermi Liquids with the microscopic constraint of a
local self-energy. In this case the forward scattering sum-rule imposes strong
limitations on the Fermi-Liquid parameters, which rule out any Pomeranchek
instabilities. For both attractive and repulsive interactions, ferromagnetism
and phase separation are suppressed. Superconductivity is possible in an s-wave
channel only. We also study the approach to the metal-insulator transition, and
find a Wilson ratio approaching 2. This ratio and other properties of
Sr_{1-x}La_xTiO_3 are all consistent with the local Fermi Liquid scenario.Comment: 4 pages (twocolumn format), can compile with or without epsf.sty
latex style file -- Postscript files: fig1.ps and fig2.p
Low-Temperature Spin Diffusion in a Spin-Polarized Fermi Gas
We present a finite temperature calculation of the transverse spin-diffusion
coefficient, , in a dilute degenerate Fermi gas in the presence of a
small external magnetic field, . While the longitudinal diffusion
coefficient displays the conventional low-temperature Fermi-liquid behavior,
, the corresponding results for show three
separate regimes: (a) for ; (b) , for and large spin-rotation
parameter , and (c) for and . Our results are qualitatively consistent with the available
experimental data in weakly spin-polarized and mixtures.Comment: 13 pages, REVTEX, 3 figures available upon request, RU-94-4
Dynamic Exponent of t-J and t-J-W Model
Drude weight of optical conductivity is calculated at zero temperature by
exact diagonalization for the two-dimensional t-J model with the two-particle
term, . For the ordinary t-J model with =0, the scaling of the Drude
weight for small doping concentration is
obtained, which indicates anomalous dynamic exponent =4 of the Mott
transition. When is switched on, the dynamic exponent recovers its
conventional value =2. This corresponds to an incoherent-to-coherent
transition associated with the switching of the two-particle transfer.Comment: LaTeX, JPSJ-style, 4 pages, 5 eps files, to appear in J. Phys. Soc.
Jpn. vol.67, No.6 (1998
Quasiparticle dynamics and phonon softening in FeSe superconductors
Quasiparticle dynamics of FeSe single crystals revealed by dual-color
transient reflectivity measurements ({\Delta}R/R) provides unprecedented
information on Fe-based superconductors. The amplitude of fast component in
{\Delta}R/R clearly tells a competing scenario between spin fluctuations and
superconductivity. Together with the transport measurements, the relaxation
time analysis further exhibits anomalous changes at 90 K and 230 K. The former
manifests a structure phase transition as well as the associated phonon
softening. The latter suggests a previously overlooked phase transition or
crossover in FeSe. The electron-phonon coupling constant {\lambda} is found to
be 0.16, identical to the value of theoretical calculations. Such a small
{\lambda} demonstrates an unconventional origin of superconductivity in FeSe.Comment: Final published version; 5 pages; 4 figure
External Device to Incrementally Skid the Habitat (E-DISH)
A Mars habitat transport system was designed as part of the NASA Mars exploration program. The transport system, the External Device to Incrementally Skid the Habitat (E - DISH), will be used to transport Mars habitats from their landing sites to the colony base and will be detached after unloading. The system requirements for Mars were calculated and scaled for model purposes. Specific model materials are commonly found and recommendations for materials for the Mars design are included
Direct Calculation of Spin-Stiffness for Spin-1/2 Heisenberg Models
The spin-stiffness of frustrated spin-1/2 Heisenberg models in one and two
dimensions is computed for the first time by exact diagonalizations on small
clusters that implement spin-dependent twisted boundary conditions. Finite-size
extrapolation to the thermodynamic limit yields a value of for
the spin-stiffness of the unfrustrated planar antiferromagnet. We also present
a general discussion of the linear-response theory for spin-twists, which
ultimately leads to the moment sum-rule.Comment: 11 pgs, TeX, LA-UR-94-94 (to be published in Phys. Rev. B
Impact of interface traps on charge noise, mobility and percolation density in Ge/SiGe heterostructures
Hole spins in Ge/SiGe heterostructure quantum dots have emerged as promising
qubits for quantum computation. The strong spin-orbit coupling (SOC),
characteristic of heavy-hole states in Ge, enables fast and all-electrical
qubit control. However, SOC also increases the susceptibility of spin qubits to
charge noise. While qubit coherence can be significantly improved by operating
at sweet spots with reduced hyperfine or charge noise sensitivity, the latter
ultimately limits coherence, underlining the importance of understanding and
reducing charge noise at its source. In this work, we study the voltage-induced
hysteresis commonly observed in SiGe-based quantum devices and show that the
dominant charge fluctuators are localized at the semiconductor-oxide interface.
By applying increasingly negative gate voltages to Hall bar and quantum dot
devices, we investigate how the hysteretic filling of interface traps impacts
transport metrics and charge noise. We find that the gate-induced accumulation
and trapping of charge at the SiGe-oxide interface leads to an increased
electrostatic disorder, as probed by transport measurements, as well as the
activation of low-frequency relaxation dynamics, resulting in slow drifts and
increased charge noise levels. Our results highlight the importance of a
conservative device tuning strategy and reveal the critical role of the
semiconductor-oxide interface in SiGe heterostructures for spin qubit
applications
Management of diarrhea in patients with HER2-positive breast cancer treated with neratinib: A case series and summary of the literature
INTRODUCTION: Neratinib and neratinib-based combinations have demonstrated efficacy for treatment of human epidermal growth factor receptor 2-positive (HER2+) early-stage and metastatic breast cancers. However, diarrhea has been reported as a common adverse event leading to neratinib discontinuation. Results from the CONTROL trial suggest that proactive diarrhea management with antidiarrheal prophylaxis or dose escalation of neratinib from a lower starting dose to the full FDA-approved dose of 240 mg/day can reduce the incidence, duration, and severity of neratinib-associated diarrhea in patients with early-stage breast cancer. Dose escalation has been included in the FDA-approved label for both early-stage and metastatic HER2+ breast cancer since June 2021.
CASE SERIES: This series of five cases details real-world clinical implementation of strategies for management of neratinib-induced diarrhea in patients with early-stage and metastatic HER2+ breast cancer, including a patient with a pre-existing gastrointestinal disorder.
MANAGEMENT AND OUTCOME: In four of five cases, diarrhea was managed with neratinib dose escalation, and antidiarrheal prophylaxis with loperamide plus colestipol was used in the remaining case. Management of diarrhea allowed all patients to remain on therapy.
DISCUSSION: This case series shows that neratinib-associated diarrhea can be managed effectively with neratinib dose escalation from a lower initial starting dose and/or prophylactic antidiarrheal medications in a real-world clinical setting. The findings highlight the importance of patient-provider communication in proactive management of adverse events. Widespread implementation of the strategies described here may improve adherence and thereby clinical outcomes for patients with HER2+ breast cancer treated with neratinib
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