The published research paper: is it an important indicator of successful operational research at programme level?

Is a published research paper an important indicator of successful operational research at programme level in low-income countries? In academia, publishing in peer-reviewed scientific journals is highly encouraged and strongly pursued for academic recognition and career progression. In contrast, for those who engage in operational research at programme level, there is often no necessity or reward for publishing the results of research studies; it may even be criticized as being an unnecessary detraction from programme-related work. We present arguments to support publishing operational research from low-income countries; we highlight some of the main reasons for failure of publication at programme level and suggest ways forward

A comparison of incompressible limits for resistive plasmas

The constraint of incompressibility is often used to simplify the magnetohydrodynamic (MHD) description of linearized plasma dynamics because it does not affect the ideal MHD marginal stability point. In this paper two methods for introducing incompressibility are compared in a cylindrical plasma model: In the first method, the limit $\gamma \to \infty$ is taken, where $\gamma$ is the ratio of specific heats; in the second, an anisotropic mass tensor $\mathbf{\rho}$ is used, with the component parallel to the magnetic field taken to vanish, $\rho_{\parallel} \to 0$. Use of resistive MHD reveals the nature of these two limits because the Alfv\'en and slow magnetosonic continua of ideal MHD are converted to point spectra and moved into the complex plane. Both limits profoundly change the slow-magnetosonic spectrum, but only the second limit faithfully reproduces the resistive Alfv\'en spectrum and its wavemodes. In ideal MHD, the slow magnetosonic continuum degenerates to the Alfv\'en continuum in the first method, while it is moved to infinity by the second. The degeneracy in the first is broken by finite resistivity. For numerical and semi-analytical study of these models, we choose plasma equilibria which cast light on puzzling aspects of results found in earlier literature.Comment: 14 pages, 10 figure

Structure, Deformations and Gravitational Wave Emission of Magnetars

Neutron stars can have, in some phases of their life, extremely strong magnetic fields, up to 10^15-10^16 G. These objects, named magnetars, could be powerful sources of gravitational waves, since their magnetic field could determine large deformations. We discuss the structure of the magnetic field of magnetars, and the deformation induced by this field. Finally, we discuss the perspective of detection of the gravitational waves emitted by these stars.Comment: 11 pages, 2 figures, prepared for 19th International Conference on General Relativity and Gravitation (GR19), Mexico City, Mexico, July 5-9, 201

Misregulation of mitochondria-lysosome contact dynamics in Charcot-Marie-Tooth Type 2B disease Rab7 mutant sensory peripheral neurons

Inter-organelle contact sites between mitochondria and lysosomes mediate the crosstalk and bidirectional regulation of their dynamics in health and disease. However, mitochondria-lysosome contact sites and their misregulation have not been investigated in peripheral sensory neurons. Charcot-Marie-Tooth type 2B disease is an autosomal dominant axonal neuropathy affecting peripheral sensory neurons caused by mutations in the GTPase Rab7. Using live super-resolution and confocal time-lapse microscopy, we showed that mitochondria-lysosome contact sites dynamically form in the soma and axons of peripheral sensory neurons. Interestingly, Charcot-Marie-Tooth type 2B mutant Rab7 led to prolonged mitochondria-lysosome contact site tethering preferentially in the axons of peripheral sensory neurons, due to impaired Rab7 GTP hydrolysis-mediated contact site untethering. We further generated a Charcot-Marie-Tooth type 2B mutant Rab7 knock-in mouse model which exhibited prolonged axonal mitochondria-lysosome contact site tethering and defective downstream axonal mitochondrial dynamics due to impaired Rab7 GTP hydrolysis as well as fragmented mitochondria in the axon of the sciatic nerve. Importantly, mutant Rab7 mice further demonstrated preferential sensory behavioral abnormalities and neuropathy, highlighting an important role for mutant Rab7 in driving degeneration of peripheral sensory neurons. Together, this study identifies an important role for mitochondria-lysosome contact sites in the pathogenesis of peripheral neuropathy

On the significance of population II Li6 abundances

We explore possible depletion factors for Li6 in the three stars where it has been detected. To this end, we assume that 6Li/H scales as 16O/H throughout the galactic evolution, an assumption motivated by the observations of a similar scaling for 9Be. We examine the uncertainties attached to this modeling of 6Li galactic evolution; we also incorporate a recent evaluation of the primordial production of 6Li. The depletion factor D6, for 6Li, in HD84937, is constrained to be less than 4 at 95% c.l.. This depletion factor is an extreme upper limit on the depletion factor for 7Li. We conclude that the primordial abundance of 7Li cannot be higher that twice the observed value, since no current stellar model is able to reproduce the observed trends of 7Li with temperature and metallicity, and yet deplete 7Li by more than a factor 2, while satisfying D6<4. All three 6Li observations are in excellent agreement with all standard expectations: Big-Bang nucleosynthesis with 2<$\eta_{10}$<6.5, and standard isochrones of 6Li survival. We discuss possible deviations from our assumption of 6Li/H scaling with 16O/H, due to alpha-alpha creation of 6Li in various sites. We notably reject stellar flares as a significant source of 6Li in HD84937.Comment: 19 pages, 4 figures, LaTeX. To appear in Ap

Pion production in the inner disk around Cygnus X-1

Neutron production via ^{4}He breakup and p(p, n{pi}^+)p is considered in the innermost region of an accretion disk surrounding a Kerr Black Hole. These reactions occur in a plasma in Wien equilibrium, where (radiatively produced) pair production equals annihilation. Cooling of the disk is assumed to be due to unsaturated inverse Comptonization of external soft photons and to the energy needed to ignite both nuclear reactions. Assuming matter composition of 90% Hydrogen and 10% He, it is shown that, close to the border of this region, neutron production is essentially from ^{4}He breakup. Close to the horizon, the contribution from p(p, n{pi}^+)p to the neutron production is comparable to that from the breakup. It is shown that the viscosity generated by the collisions of the accreting matter with the neutrons may drive stationary accretion, for accretion rates below a critical value. In this case, solution to the disk equations is double-valued and for both solutions protons overnumber the pairs. It is claimed that these solutions may mimic the states of high and low luminosity observed in Cygnus X-1 and related sources. This would be explained either by the coupling of thermal instability to the peculiar behavior of the viscosity parameter alpha with the ion temperature that may intermittently switch accretion off or by the impossibility of a perfect tuning for both thermal and pair equilibrium in the disk, a fact that forces the system to undergo a kind of limit cycle behavior around the upper solution.Comment: 23 pages, 11 figure

Band-width control in a perovskite-type 3d^1 correlated metal Ca_{1-x}Sr_xVO_3. I. Evolution of the electronic properties and effective mass

Single crystals of the perovskite-type $3d^{1}$ metallic alloy system Ca$_{1-x}$Sr$_x$VO$_3$ were synthesized in order to investigate metallic properties near the Mott transition. The substitution of a Ca$^{2+}$ ion for a Sr$^{2+}$ ion reduces the band width $W$ due to a buckling of the V-O-V bond angle from $\sim180^\circ$ for SrVO$_3$ to $\sim160^\circ$ for CaVO$_3$. Thus, the value of $W$ can be systematically controlled without changing the number of electrons making Ca$_{1-x}$Sr$_x$VO$_3$: one of the most ideal systems for studying band-width effects. The Sommerfeld-Wilson's ratio ($\simeq2$), the Kadowaki-Woods ratio (in the same region as heavy Fermion systems), and a large $T^{2}$ term in the electric resistivity, even at 300 K, substantiate a large electron correlation in this system, though the effective mass, obtained by thermodynamic and magnetic measurements, shows only a systematic but moderate increase in going from SrVO$_3$ to CaVO$_3$, in contrast to the critical enhancement expected from the Brinkmann-Rice picture. It is proposed that the metallic properties observed in this system near the Mott transition can be explained by considering the effect of a non-local electron correlation.Comment: 14 pages in a Phys. Rev. B camera-ready format with 10 EPS figures embedded. LaTeX 2.09 source file using "camera.sty" and "prbplug.sty" provided by N. Shirakawa. For OzTeX (Macintosh), use "ozfig.sty" instead of "psfig.sty". "ozfig.sty" can be also obtained by e-mail request to N. Shirakawa: . Submitted to Phys. Rev.

Bondi-Hoyle-Lyttleton Accretion Model for Low-luminosity X-ray Sources in Globular Clusters

We present a new model for low-luminosity X-ray sources in globular clusters, with L_x < 10^34 erg/s. The model we propose is that of a single neutron star accreting from cluster gas that has accumulated as a natural product of stellar evolution. An analytic luminosity function is derived under the assumption that the speed distribution of neutron stars in the central region of a cluster is described by a Maxwellian, and that the density and temperature of the gas are uniform. Predictions of the model and implications for the gas content of globular clusters are discussed.Comment: Accepted by ApJ. Minor changes and expanded conclusions sectio