34 research outputs found
Connection between dynamics and thermodynamics of liquids on the melting line
The dynamics of a large number of liquids and polymers exhibit scaling
properties characteristic of a simple repulsive inverse power law (IPL)
potential, most notably the superpositioning of relaxation data as a function
of the variable TV{\gamma}, where T is temperature, V the specific volume, and
{\gamma} a material constant. A related scaling law, TmVm{\Gamma}, with the
same exponent {\Gamma}={\gamma}, links the melting temperature Tm and volume Vm
of the model IPL liquid; liquid dynamics is then invariant at the melting
point. Motivated by a similar invariance of dynamics experimentally observed at
transitions of liquid crystals, we determine dynamic and melting point scaling
exponents {\gamma} and {\Gamma} for a large number of non-associating liquids.
Rigid, spherical molecules containing no polar bonds have {\Gamma}={\gamma};
consequently, the reduced relaxation time, viscosity and diffusion coefficient
are each constant along the melting line. For other liquids {\gamma}>{\Gamma}
always; i.e., the dynamics is more sensitive to volume than is the melting
point, and for these liquids the dynamics at the melting point slows down with
increasing Tm (that is, increasing pressure).Comment: 20 pages, 8 figures, 1 tabl
On the correlation between fragility and stretching in glassforming liquids
We study the pressure and temperature dependences of the dielectric
relaxation of two molecular glassforming liquids, dibutyl phtalate and
m-toluidine. We focus on two characteristics of the slowing down of relaxation,
the fragility associated with the temperature dependence and the stretching
characterizing the relaxation function. We combine our data with data from the
literature to revisit the proposed correlation between these two quantities. We
do this in light of constraints that we suggest to put on the search for
empirical correlations among properties of glassformers. In particular, argue
that a meaningful correlation is to be looked for between stretching and
isochoric fragility, as both seem to be constant under isochronic conditions
and thereby reflect the intrinsic effect of temperature
Quantum correlations in Newtonian space and time: arbitrarily fast communication or nonlocality
We investigate possible explanations of quantum correlations that satisfy the
principle of continuity, which states that everything propagates gradually and
continuously through space and time. In particular, following [J.D. Bancal et
al, Nature Physics 2012], we show that any combination of local common causes
and direct causes satisfying this principle, i.e. propagating at any finite
speed, leads to signalling. This is true even if the common and direct causes
are allowed to propagate at a supraluminal-but-finite speed defined in a
Newtonian-like privileged universal reference frame. Consequently, either there
is supraluminal communication or the conclusion that Nature is nonlocal (i.e.
discontinuous) is unavoidable.Comment: It is an honor to dedicate this article to Yakir Aharonov, the master
of quantum paradoxes. Version 2 contains some more references and a clarified
conclusio
Information Causality and Extremal Tripartite Correlations
We study the principle of information causality for the set of extremal
correlations in the tripartite scenario. We show that all but one nonlocal
extremal correlations in this scenario violate information causality. This
undetected correlation is shown to satisfy any bipartite physical principle.Comment: 8 pages, 2 figures. Minor corrections and improvement to the proof in
appendi
An integrated view of theiInfluence of temperature, pressure, and humidity on the stability of trimorphic cysteamine hydrochloride
Understanding the phase behavior of pharmaceuticals is important for dosage form development and regulatory requirements, in particular after the incident with ritonavir. In the present paper, a comprehensive study of the solid-state phase behavior of cysteamine hydrochloride used in the treatment of nephropathic cystinosis and recently granted orphan designation by the European Commission is presented employing (high-pressure) calorimetry, water vapor sorption, and X-ray diffraction as a function of temperature. A new crystal form (I2/a, form III) has been discovered, and its structure has been solved by X-ray powder diffraction, while two other crystalline forms are already known. The relative thermodynamic stabilities of the commercial form I and of the newly discovered form III have been established; they possess an overall enantiotropic phase relationship, with form I stable at room temperature and form III stable above 37 degrees C. Its melting temperature was found at 67.3 +/- 0.5 degrees C. Cysteamine hydrochloride is hygroscopic and immediately forms a concentrated saturated solution in water with a surprisingly high concentration of 47.5 mol % above a relative humidity of 35%. No hydrate has been observed. A temperature composition phase diagram is presented that has been obtained with the unary pressure temperature phase diagram, measurements, and calculations. For development, form I would be the best form to use in any solid dosage form, which should be thoroughly protected against humidity.Postprint (author's final draft
Thermal and X-ray measurements on -hexatriacontane (CH)
The polymorphism of n-hexatriacontane (CH) was investigated by X-ray diffraction and DSC thermal analysis. CH displays at least two stable monoclinic phases and a rotator phase. Starting from a
solution-grown sample of very high purity the following phases are observed with increasing temperature: M011 345K M101 346K RIII 348K liquid. Depending on the thermal treatment also other forms may be
obsaved. During these transitions, both the crystalline volume and the lamellar thickness increase. The higher
order reflections of the layer structure was precisely measured by X-ray diffraction. Using a Fourier synthesis,
electron density profiles of the three phases were analysed. The results show that the interlamellar structure is
disturbed by inaeasing molecular motions with elevating temperatures. For some homologous alkanes also p(T)
phase diagrams and binary systems have been studied