ATLAS detector with cosmic rays and expected performance with early data

Cosmic muons have helped to understand the ATLAS detector in terms of DAQ, trigger, alignment and calibration. I briefly review the performance of the ATLAS Inner Detector, Calorimeters and Muon Spectrometer systems with cosmic rays. The expected performance with first LHC collisions will also be reviewed

Membrane Surface Engineering for Biochemical Applications

Synthetic membranes have been frequently used for many fields, such as, the food and beverage, biopharmaceutical, and biofuel industries. In the beer industry, microfiltration frequently suffers from fouling due to the interaction between different species. It is shown that polyphenols can form cross-links with protein molecules, forming insoluble aggregates. However, by adding an optimal amount of polysaccharides these aggregates can be disrupted thus reducing fouling by the aggregates. Confocal laser scanning microscopy (CLSM) is a powerful technique to locate the foulants inside the wet membrane in order to understand more about the behavior of fouling in microfiltration. Membrane surface modification is used to impart desirable membrane surface properties. Here membrane surface modification is used to develop membrane adsorbers for protein purification. Hydrophobic interaction membrane chromatography (HIMC) has gained interest due to its excellent performance in purification humanized monoclonal antibodies. HIMC affords all the advantages of membrane adsorbers, which is dynamic capacities that are independent of flow rate, higher throughput and easy to scale up. Unique inverse colloidal crystal (ICC) membranes were developed with highly periodic structures, high porosity, and fully interconnected pores. ICC membranes offer a very high binding capacity for IgG4. On the other hand, salt responsive membranes were developed by grafting responsive ligand, poly vinylcaprolactam (PVCL), from the surface of the membrane by atom transfer radical polymerization (ATRP). The nanostructure can vary its conformation and hydrophobicity when the temperature changes. After modification, membrane is able to provide a very high recovery and yield. Membrane modification is also well applied for biofuel industry. Duel nanostructures, poly styrene sulfonic acid (PSSA) and poly ionic liquid (PIL) were grafted separately and neighborly from the surface of ceramic membrane substrate by control ATRP and UV initiated radical polymerization. Modified membrane substrates were challenged with cellulose and corn-stovers biomass hydrolysis in pure ionic liquid (IL) and mixture of IL and co-solvent. High yield in total reducing sugar (TRS), 95% and 60% for cellulose and corn-stovers biomass respectively, indicates strong activity of polymeric solid acid catalysts

The millipede family Polydesmidae Leach, 1816 (Diplopoda, Polydesmida) from Vietnam, with a description of a new cavernicolous species

The millipede family Polydesmidae Leach, 1816 is reviewed in the scope of the Vietnamese fauna. The distribution of the species, Polydesmus vietnamicus Nguyen, 2009 is extended northward to Ha Giang Province. A new cavernicolous polydesmid, Pacidesmus tuachua sp. nov., is described from two caves in northwestern Vietnam, representing the first record of the genus from Vietnam. Extensive illustrations and DNA barcodes are provided for both species, a revised key is presented to all 12 species of Pacidesmus Golovatch, 1991, as well as a key to all eight genera of Asian Polydesmidae

Conditional expectation with regularization for missing data imputation

Missing data frequently occurs in datasets across various domains, such as medicine, sports, and finance. In many cases, to enable proper and reliable analyses of such data, the missing values are often imputed, and it is necessary that the method used has a low root mean square error (RMSE) between the imputed and the true values. In addition, for some critical applications, it is also often a requirement that the imputation method is scalable and the logic behind the imputation is explainable, which is especially difficult for complex methods that are, for example, based on deep learning. Based on these considerations, we propose a new algorithm named "conditional Distribution-based Imputation of Missing Values with Regularization" (DIMV). DIMV operates by determining the conditional distribution of a feature that has missing entries, using the information from the fully observed features as a basis. As will be illustrated via experiments in the paper, DIMV (i) gives a low RMSE for the imputed values compared to state-of-the-art methods; (ii) fast and scalable; (iii) is explainable as coefficients in a regression model, allowing reliable and trustable analysis, makes it a suitable choice for critical domains where understanding is important such as in medical fields, finance, etc; (iv) can provide an approximated confidence region for the missing values in a given sample; (v) suitable for both small and large scale data; (vi) in many scenarios, does not require a huge number of parameters as deep learning approaches; (vii) handle multicollinearity in imputation effectively; and (viii) is robust to the normally distributed assumption that its theoretical grounds rely on

Accumulation and distribution of zinc in the leaves and roots of the hyperaccumulator Noccaea caerulescens

Understanding the uptake mechanisms of heavy metals by hyperaccumulators is necessary for improving phytoextraction options to reduce metal toxicities in contaminated soils. In this study, the capacity of Zn uptake by the hyperaccumulator Noccaea caerulescens was investigated and compared to the non-hyperaccumulator Thlaspi arvense. The plants were grown under hydroponic conditions in a glasshouse. The distribution of Zn in the roots and leaves of these species was investigated by scanning electron microscopy with energy-dispersive X-ray analysis. Compared with the control with no Zn added, it was shown that prolonged Zn treatments decreased the biomass of both N. caerulescens and T. arvense. Since N. caerulescens requires Zn for growth, no Zn toxicity symptoms were observed, even when the Zn concentration in shoots reached 2.5% dry mass. T. arvense showed serious Zn toxicity only after two weeks of Zn treatment. Zn uptake by N. caerulescens was mainly translocated to the leaves while almost all of the Zn taken-up by T. arvense was retained in the roots. In N. caerulescens, increasing concentration of Zn in the supply decreased Ca and P concentrations in the shoots by up to 50 and 35%, respectively. Zn-containing crystals were abundant in both the upper and lower epidermal cells of the leaves and in the cortex of the roots during the later growth phase. Co-localization of Ca and Zn, P and S were found in leaf and root tissues. The results suggest that Zn-rich crystals with an abundance of the Zn ligand in the roots and shoots, and co-localization and interaction between Zn and other ions, may have functional significance with respect to conferring particular attributes to N. caerulescens that are not present in the non-hyperaccumulator counterpart. An understanding of these species-specific differences has relevance from the perspective of offering some insight into how particular species could contribute to a strategy for the detoxification of Zn-contaminated sites

Extremely Hot Ambient Temperature and Injury-related Mortality

This pilot study aimed to evaluate the effects of extremely hot ambient temperatures on the total number of fatal injuries. Data were collected from a population-based mortality registry of Thanh Hoa, a province in the North Central region of Vietnam. This study qualified the distributed lag non-linear model and calculated the RR and 95% CI adjusted for long-term trend and absolute humidity. For the entire study population with 3,949 registered deaths due to injuries collected during 2005-2007, after the onset of extremely hot ambient temperatures, an increased risk of death was observed on the 9th day RR (95% CI) = 1.44 (1.06–1.97) and reached the peak on the 12th day RR (95% CI) = 1.58 (1.14–2.17), and at the 15th day RR (95% CI) = 1.49 (1.08–2.06). Men and old adults were identified as the most vulnerable groups. This study confirmed a positive association between hot temperatures and injury-related deaths in the province of 3.6 million people. The findings motivated further investigation into the effect of warm climate changes and the risk of deaths related to other specific causes such as road traffic, work-related injury, and etc