36 Months Survivability And Its Predictors In Patients With Chronic Heart Failure And Decreased Fraction Of Left Ventricular Ejection Depending On Sex

Aim of the work: to compare survivability parameters during 36 months and their predictors among men and women with chronic heart failure and decreased fraction of left ventricular ejection.Materials and methods: the research included 356 patients with CHF (NYHA ІІ –ІV) with decreased LVEF<40 %, 18–75 years old. Using Kaplan-Meier method, there was analyzed the survivability in men and women during 36 months, then there were analyzed independent factors that influenced survivability terms depending on sex using the multiple logistic regression.Results. Our analysis of the survivability of patients with CHF with decreased LVEF demonstrated that the cumulative survival after 3 years of observation was 49 and 51 % for men and women, respectively. The curves of 36 months survivability didn\u27t reliably differ. At the analysis of factors, associated with the bad prognosis, there were observed differences between groups of men and women with CHF. Thus, in men the predictors of 36 month survival were: the thickness of the right ventricle wall, size of the right atrium, end-diastolic volume and end-systolic volume of LV, indices of EDV and ESV of LV, urinary acid level, value of LVEF. In women the predictors of survivability during 3 years were the following parameters: BMI, DM type 2 in an anamnesis, end-diastolic size of LV, end-systolic size of LV, blood glucose level, LVEF.Conclusion. The survivability of men and women with CHF with decreased LVEF during 36 months didn\u27t reliably differ and was 49 and 51 % respectively. But predictors of the lethal outcome in men and women essentially differed during 36 months, and their number is essentially higher in men

Metallic water: transient state under ultrafast electronic excitation

The modern means of controlled irradiation by femtosecond lasers or swift heavy ion beams can transiently produce such energy densities in samples that reach collective electronic excitation levels of the warm dense matter state where the potential energy of interaction of the particles is comparable to their kinetic energies (temperatures of a few eV). Such massive electronic excitation severely alters the interatomic potentials, producing unusual nonequilibrium states of matter and different chemistry. We employ density functional theory and tight binding molecular dynamics formalisms to study the response of bulk water to ultrafast excitation of its electrons. After a certain threshold electronic temperature, the water becomes electronically conducting via the collapse of its band gap. At high doses, it is accompanied by nonthermal acceleration of ions to a temperature of a few thousand Kelvins within sub-100 fs timescales. We identify the interplay of this nonthermal mechanism with the electron-ion coupling, enhancing the electron-to-ions energy transfer. Various chemically active fragments are formed from the disintegrating water molecules, depending on the deposited dose.Comment: to be submitte

Search for ionized jets towards high-mass young stellar objects

We are carrying out multi-frequency radio continuum observations, using the Australia Telescope Compact Array, to systematically search for collimated ionized jets towards high-mass young stellar objects (HMYSOs). Here we report observations at 1.4, 2.4, 4.8 and 8.6 GHz, made with angular resolutions of about 7, 4, 2, and 1 arcsec, respectively, towards six objects of a sample of 33 southern HMYSOs thought to be in very early stages of evolution. The objects in the sample were selected from radio and infrared catalogs by having positive radio spectral indices and being luminous (L_bol > 20,000 L_sun), but underluminous in radio emission compared to that expected from its bolometric luminosity. This criteria makes the radio sources good candidates for being ionized jets. As part of this systematic search, two ionized jets have been discovered: one previously published and the other reported here. The rest of the observed candidates correspond to three hypercompact hii regions and two ultracompact hii regions. The two jets discovered are associated with two of the most luminous (70,000 and 100,000 Lsun) HMYSOs known to harbor this type of objects, showing that the phenomena of collimated ionized winds appears in the formation process of stars at least up to masses of ~ 20 M_sun and provides strong evidence for a disk-mediated accretion scenario for the formation of high-mass stars. From the incidence of jets in our sample, we estimate that the jet phase in high-mass protostars lasts for 40,000 yr.Comment: Accepted for publication in the Astrophysical Journal. (53 pages, 22 Figures) (Color figures were degraded to comply with arXiv requirements