Use of outdoor games in physical rehabilitation of children with a cerebral paralysis.

We considered the estimation of energy in children's organism with cerebral paralysis. 16 children of secondary school age took part in research with spastic forms of a cerebral paralysis. It is established that children with a cerebral paralysis have the reduced energy parameters of the organism in comparison with children of the basic group of health. It is proved that specially organized outdoor games at the studies contribute to the growth of these indicators

Cervical carcinoma: Oncobiology and biomarkers

Cervical cancer is one of the most common types of carcinomas causing morbidity and mortality in women in all countries of the world. At the moment, the oncology, oncobiology, and on-comorphology of cervical cancer are characterized by the accumulation of new information; various molecular biological, genetic, and immunohistochemical methods of investigation of the mechanisms of cervical carcinogenesis are tested and applied; targeted antitumour drugs and diagnostic, prog-nostic, and predictive biomarkers are being searched for. Many issues of the etiopathogenesis of cervical cancer have not been sufficiently studied, and the role of many biomarkers characterizing various stages of cervical carcinogenesis remains unclear. Therefore, the target of this review is to systematize and understand several problems in the pathogenesis of cervical cancer and to evaluate the significance and role of biomarkers in cervical carcinogenesis. © 2021 by the authors. Licensee MDPI, Basel, Switzerland

На пути к автоматизированному мета-анализу биомедицинских текстов в области клеточной иммунотерапии

Cell-based immunotherapy is a promising approach for the treatment of chronic infections, autoimmune disorders, and malignant tumors. There are many strategies of cell-based immunotherapy of cancer; these include injection of various immune effector cells, propagated and «trained» in a cell culture. Alternatively, cells presenting tumor antigens on their surface in a form recognized by the immune system can be used to achieve a therapeutic effect. The research results in this field are presented in thousands of texts, and their manual analysis is very complicated. We have developed an approach for automated text analysis in this area of biomedical science. Here we present the first results of the automated analysis of the data extracted from abstracts of scientific articles available in PubMed. These results demonstrate the associations between types of tumors and the most commonly used methods of their cell-based immunotherapy.Клеточная иммунотерапия это перспективный подход к лечению хронических инфекций, аутоиммунных нарушений и злокачественных опухолей. Существует множество стратегий иммунотерапии рака, включая инъекции различных иммунных эффекторных клеток, размноженных и «обученных» в клеточной культуре. В качестве альтернативы для достижения терапевтического эффекта могут быть использованы клетки, представляющие опухолевый антиген на своей поверхности в «понятном» для иммунной системы виде. Результаты исследований в этой области представлены в тысячах текстов, ручной анализ которых затруднен. Мы разработали подход для автоматического анализа текстов в этой области биомедицинской науки. В данной работе мы представляем первые результаты автоматического анализа данных, извлеченных из абстрактов научных статей, доступных в PubMed. На корпусе извлеченных текстов мы демонстрируем ассоциации между типами опухолей и наиболее часто используемыми способами клеточной терапии