Another look at the dayside spectra of WASP-43b and HD 209458b: are there scattering clouds?

The search for clouds on the dayside of hot Jupiters has been disadvantaged due to hot Jupiters having a limited number of high quality space-based observations. To date, retrieval studies have found no evidence for grey clouds on the dayside, however none of these studies explored the impact of scattering clouds. In this study we reanalyse the dayside emission spectrum of the hot Jupiter WASP-43b considering the different Spitzer data in the literature. We find that, in 2 of the 4 data sets explored, retrieving with a model that contains a scattering cloud is favoured over a cloud free model by a confidence of 3.13 - 3.36 $\sigma$. The other 2 data sets finds no evidence for scattering clouds. We find that the retrieved H$_2$O abundance is consistent regardless of the Spitzer data used and is consistent with literature values. We perform the same analysis for the hot Jupiter HD 209458b and find no evidence for dayside clouds, consistent with previous studies.Comment: 7 pages, 6 figures. Accepted for publication with MNRA

DNA Unicorn: An N-of-1 Community Advocacy Resource

With the wider use of genetic testing, an increasing number of people are receiving molecular diagnoses of ultra-rare or N-of-1 diseases. The medical and psychosocial challenges of these individuals are compounded by a lack of support and advice from disease-specific communities. A website ( www.dnaunicorn.org) was developed to help N-of-1 families connect with caregivers, researchers, and patients with the same or related medical conditions. The site provides directions and links to resources to facilitate data-sharing through access to databases, and aids in the construction of social media campaigns to connect genotypically- or phenotypically-related patients and families to each other. Furthermore, the website provides step-by-step instructions and templates for users to optimize their use of Twitter, Facebook, GenomeConnect, MyGene2 and other potential avenues to find and build a community. Fourteen genetic counselors provided feedback by answering seven questions on the usefulness of an early version of the web-based tool kit. Free text responses were also elicited. Five themes emerged in qualitative analysis of their responses: aesthetics, language, resource choice, how-to guide utility, and overall clinical utility. Aesthetics was mentioned most frequently, with eight genetic counselors commenting on font size and text placement. Responses to the website were overwhelmingly positive; 100% of participants agreed that it would be useful in clinical practice and would refer patients to the website. Counselors also described a need for more resources for families with N-of-1 or ultra-rare molecular diagnoses, which our site attempts to address