Conflict of Laws - Jurisdiction - Minimum Contacts

The outer limits of constitutionally valid jurisdiction are not exceeded by asserting jurisdiction over a service corporation doing business solely in a foreign state, if such corporation does a negligent act in the foreign state which causes injury in the state of the forum. Roche v. Floral Rental Corporation, 95 N.J. Super. 555, 232 A.2d 162 (1967), appeal docketed, No.___, N.J. Sup. Ct. (1967)

Measurement of the J/ψ pair production cross-section in pp collisions at s=13 \sqrt{s}=13 TeV

The production cross-section of J/ψ pairs is measured using a data sample of pp collisions collected by the LHCb experiment at a centre-of-mass energy of $\sqrt{s}=13$ TeV, corresponding to an integrated luminosity of 279 ±11 pb$^{−1}$. The measurement is performed for J/ψ mesons with a transverse momentum of less than 10 GeV/c in the rapidity range 2.0 < y < 4.5. The production cross-section is measured to be 15.2 ± 1.0 ± 0.9 nb. The first uncertainty is statistical, and the second is systematic. The differential cross-sections as functions of several kinematic variables of the J/ψ pair are measured and compared to theoretical predictions.The production cross-section of $J/\psi$ pairs is measured using a data sample of $pp$ collisions collected by the LHCb experiment at a centre-of-mass energy of $\sqrt{s} = 13 \,{\mathrm{TeV}}$, corresponding to an integrated luminosity of $279 \pm 11 \,{\mathrm{pb^{-1}}}$. The measurement is performed for $J/\psi$ mesons with a transverse momentum of less than $10 \,{\mathrm{GeV}}/c$ in the rapidity range $2.0<y<4.5$. The production cross-section is measured to be $15.2 \pm 1.0 \pm 0.9 \,{\mathrm{nb}}$. The first uncertainty is statistical, and the second is systematic. The differential cross-sections as functions of several kinematic variables of the $J/\psi$ pair are measured and compared to theoretical predictions

Measurements of prompt charm production cross-sections in pp collisions at s=5 \sqrt{s}=5 TeV

Production cross-sections of prompt charm mesons are measured using data from $pp$ collisions at the LHC at a centre-of-mass energy of $5\,$TeV. The data sample corresponds to an integrated luminosity of $8.60\pm0.33\,$pb$^{-1}$ collected by the LHCb experiment. The production cross-sections of $D^0$, $D^+$, $D_s^+$, and $D^{*+}$ mesons are measured in bins of charm meson transverse momentum, $p_{\text{T}}$, and rapidity, $y$. They cover the rapidity range $2.0 < y < 4.5$ and transverse momentum ranges $0 < p_{\text{T}} < 10\, \text{GeV}/c$ for $D^0$ and $D^+$ and $1 < p_{\text{T}} < 10\, \text{GeV}/c$ for $D_s^+$ and $D^{*+}$ mesons. The inclusive cross-sections for the four mesons, including charge-conjugate states, within the range of $1 < p_{\text{T}} < 8\, \text{GeV}/c$ are determined to be \begin{equation*} \sigma(pp\rightarrow D^0 X) = 1190 \pm 3 \pm 64\,\mu\text{b} \end{equation*} \begin{equation*} \sigma(pp\rightarrow D^+ X) = 456 \pm 3 \pm 34\,\mu\text{b} \end{equation*} \begin{equation*} \sigma(pp\rightarrow D_s^+ X) = 195 \pm 4 \pm 19\,\mu\text{b} \end{equation*} \begin{equation*} \sigma(pp\rightarrow D^{*+} X)= 467 \pm 6 \pm 40\,\mu\text{b} \end{equation*} where the uncertainties are statistical and systematic, respectively.Production cross-sections of prompt charm mesons are measured using data from pp collisions at the LHC at a centre-of-mass energy of 5 TeV. The data sample corresponds to an integrated luminosity of 8.60 ± 0.33 pb$^{−1}$ collected by the LHCb experiment. The production cross-sections of D$^{0}$, D$^{+}$, D$_{s}^{+}$ , and D$^{∗+}$ mesons are measured in bins of charm meson transverse momentum, p$_{T}$, and rapidity, y. They cover the rapidity range 2.0 < y < 4.5 and transverse momentum ranges 0 < p$_{T}$ < 10 GeV/c for D$^{0}$ and D$^{+}$ and 1 < p$_{T}$ < 10 GeV/c for D$_{s}^{+}$ and D$^{∗+}$ mesons. The inclusive cross-sections for the four mesons, including charge-conjugate states, within the range of 1 < p$_{T}$ < 8 GeV/c are determined to be $\begin{array}{l}\sigma \left( pp\to {D}^0X\right)=1004\pm 3\pm 54\mu \mathrm{b},\\ {}\sigma \left( pp\to {D}^{+}X\right)=402\pm 2\pm 30\mu \mathrm{b},\\ {}\sigma \left( pp\to {D}_s^{+}X\right)=170\pm 4\pm 16\mu \mathrm{b},\\ {}\sigma \left( pp\to {D}^{\ast +}X\right)=421\pm 5\pm 36\mu \mathrm{b},\end{array}$ where the uncertainties are statistical and systematic, respectively.Production cross-sections of prompt charm mesons are measured using data from $pp$ collisions at the LHC at a centre-of-mass energy of $5\,$TeV. The data sample corresponds to an integrated luminosity of $8.60\pm0.33\,$pb$^{-1}$ collected by the LHCb experiment. The production cross-sections of $D^0$, $D^+$, $D_s^+$, and $D^{*+}$ mesons are measured in bins of charm meson transverse momentum, $p_{\text{T}}$, and rapidity, $y$. They cover the rapidity range $2.0<y<4.5$ and transverse momentum ranges $0 < p_{\text{T}} < 10\, \text{GeV}/c$ for $D^0$ and $D^+$ and $1 < p_{\text{T}} < 10\, \text{GeV}/c$ for $D_s^+$ and $D^{*+}$ mesons. The inclusive cross-sections for the four mesons, including charge-conjugate states, within the range of $1 < p_{\text{T}} < 8\, \text{GeV}/c$ are determined to be \sigma(pp\rightarrow D^0 X) = 1004 \pm 3 \pm 54\,\mu\text{b} \sigma(pp\rightarrow D^+ X) = 402 \pm 2 \pm 30\,\mu\text{b} \sigma(pp\rightarrow D_s^+ X) = 170 \pm 4 \pm 16\,\mu\text{b} \sigma(pp\rightarrow D^{*+} X)= 421 \pm 5 \pm 36\,\mu\text{b} where the uncertainties are statistical and systematic, respectively

SARS-CoV-2 productively infects primary human immune system cells in vitro and in COVID-19 patients

Abstract: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with a hyperinflammatory state and lymphocytopenia, a hallmark that appears as both signature and prognosis of disease severity outcome. Although cytokine storm and a sustained inflammatory state are commonly associated with immune cell depletion, it is still unclear whether direct SARS-CoV-2 infection of immune cells could also play a role in this scenario by harboring viral replication. We found that monocytes, as well as both B and T lymphocytes, were susceptible to SARS-CoV-2 infection in vitro, accumulating double-stranded RNA consistent with viral RNA replication and ultimately leading to expressive T cell apoptosis. In addition, flow cytometry and immunofluorescence analysis revealed that SARS-CoV-2 was frequently detected in monocytes and B lymphocytes from coronavirus disease 2019 (COVID-19) patients. The rates of SARS-CoV-2-infected monocytes in peripheral blood mononuclear cells from COVID-19 patients increased over time from symptom onset, with SARS-CoV-2-positive monocytes, B cells, and CD4+ T lymphocytes also detected in postmortem lung tissue. These results indicated that SARS-CoV-2 infection of blood-circulating leukocytes in COVID-19 patients might have important implications for disease pathogenesis and progression, immune dysfunction, and virus spread within the host

Observation of the B+→D∗−K+π+B^+ \to D^{*-}K^+\pi^+ decay

The B+→D*-K+π+ decay potentially provides an excellent way to investigate charm meson spectroscopy. The decay is searched for in a sample of proton-proton collision data collected with the LHCb detector at center-of-mass energies of 7 and 8 TeV, corresponding to an integrated luminosity of 3  fb-1. A clear signal is observed, and the ratio of its branching fraction to that of the B+→D*-π+π+ normalization channel is measured to be B(B+→D*-K+π+)/B(B+→D*-π+π+)=(6.39±0.27±0.48)×10-2, where the first uncertainty is statistical and the second is systematic. This is the first observation of the B+→D*-K+π+ decay.The $B^+ \to D^{*-}K^+\pi^+$ decay potentially provides an excellent way to investigate charm meson spectroscopy. The decay is searched for in a sample of proton-proton collision data collected with the LHCb detector at centre-of-mass energies of 7 and 8 TeV, corresponding to an integrated luminosity of $3~{\rm fb}^{-1}$. A clear signal is observed, and the ratio of its branching fraction to that of the $B^+ \to D^{*-}\pi^+\pi^+$ normalisation channel is measured to be \begin{equation*} \frac{\mathcal{B}(B^+ \to D^{*-}K^+\pi^+)}{\mathcal{B}(B^+ \to D^{*-}\pi^+\pi^+)} = \left( 6.39 \pm 0.27 \pm 0.48 \right) \times 10^{-2} \, , \end{equation*} where the first uncertainty is statistical and the second is systematic. This is the first observation of the $B^+ \to D^{*-}K^+\pi^+$ decay

Observation of the Ξb−→J/ψΛK−\varXi^{-}_{b}\to J/\psi\varLambda K^{-} decay

The observation of the decay $\varXi_{b}^{-}\to J/\psi\varLambda K^{-}$ is reported, using a data sample corresponding to an integrated luminosity of $3~\mathrm{fb}^{-1}$, collected by the LHCb detector in $pp$ collisions at centre-of-mass energies of $7$ and $8~\mathrm{TeV}$. The production rate of $\varXi_{b}^{-}$ baryons detected in the decay $\varXi_{b}^{-}\to J/\psi\varLambda K^{-}$ is measured relative to that of $\varLambda_{b}^{0}$ baryons using the decay $\varLambda_{b}^{0}\to J/\psi \varLambda$. Integrated over the $b$-baryon transverse momentum $p_{\rm T}<25~\mathrm{GeV/}c$ and rapidity $2.0 < y < 4.5$, the measured ratio is \begin{equation*} \frac{f_{\varXi_{b}^{-}}}{f_{\varLambda_{b}^{0}}}\frac{\mathcal{B}(\varXi_{b}^{-}\to J/\psi\varLambda K^{-})}{\mathcal{B}(\varLambda_{b}^{0}\to J/\psi \varLambda)}=(4.19\pm 0.29~(\mathrm{stat})\pm0.14~(\mathrm{syst}))\times 10^{-2}, \end{equation*}where $f_{\varXi_{b}^{-}}$ and $f_{\varLambda_{b}^{0}}$ are the fragmentation fractions of $b\to\varXi_{b}^{-}$ and $b\to\varLambda_{b}^{0}$ transitions, and $\mathcal{B}$ represents the branching fraction of the corresponding $b$-baryon decay. The mass difference between $\varXi_{b}^{-}$ and $\varLambda_{b}^{0}$ baryons is measured to be \begin{equation*} M(\varXi_{b}^{-})-M(\varLambda_{b}^{0})=177.08\pm0.47~(\mathrm{stat})\pm0.16~(\mathrm{syst} )~\mathrm{MeV/}c^{2}. \end{equation*}The observation of the decay Ξb−→J/ψΛK− is reported, using a data sample corresponding to an integrated luminosity of 3fb−1 , collected by the LHCb detector in pp collisions at centre-of-mass energies of 7 and 8TeV . The production rate of Ξb− baryons detected in the decay Ξb−→J/ψΛK− is measured relative to that of Λb0 baryons using the decay Λb0→J/ψΛ . Integrated over the b -baryon transverse momentum pT<25GeV/c and rapidity 2.0<y<4.5 , the measured ratio is fΞb−fΛb0B(Ξb−→J/ψΛK−)B(Λb0→J/ψΛ)=(4.19±0.29 (stat)±0.15 (syst))×10−2, where fΞb− and fΛb0 are the fragmentation fractions of b→Ξb− and b→Λb0 transitions, and B represents the branching fraction of the corresponding b -baryon decay. The mass difference between Ξb− and Λb0 baryons is measured to be M(Ξb−)−M(Λb0)=177.08±0.47 (stat)±0.16 (syst)MeV/c2.The observation of the decay $\varXi^{-}_{b}\to J/\psi\varLambda K^{-}$ is reported, using a data sample corresponding to an integrated luminosity of $3~\mathrm{fb}^{-1}$, collected by the LHCb detector in $pp$ collisions at centre-of-mass energies of $7$ and $8~\mathrm{TeV}$. The production rate of $\varXi_{b}^{-}$ baryons detected in the decay $\varXi_{b}^{-}\to J/\psi\varLambda K^{-}$ is measured relative to that of $\varLambda_{b}^{0}$ baryons using the decay $\varLambda_{b}^{0}\to J/\psi \varLambda$. Integrated over the $b$-baryon transverse momentum $p_{\rm T}<25~\mathrm{GeV/}c$ and rapidity $2.0<y<4.5$, the measured ratio is \begin{equation*} \frac{f_{\varXi_{b}^{-}}}{f_{\varLambda_{b}^{0}}}\frac{\mathcal{B}(\varXi_{b}^{-}\to J/\psi\varLambda K^{-})}{\mathcal{B}(\varLambda_{b}^{0}\to J/\psi \varLambda)}=(4.19\pm 0.29~(\mathrm{stat})\pm0.15~(\mathrm{syst}))\times 10^{-2}, \end{equation*}where $f_{\varXi_{b}^{-}}$ and $f_{\varLambda_{b}^{0}}$ are the fragmentation fractions of $b\to\varXi_{b}^{-}$ and $b\to\varLambda_{b}^{0}$ transitions, and $\mathcal{B}$ represents the branching fraction of the corresponding $b$-baryon decay. The mass difference between $\varXi_{b}^{-}$ and $\varLambda_{b}^{0}$ baryons is measured to be \begin{equation*} M(\varXi_{b}^{-})-M(\varLambda_{b}^{0})=177.08\pm0.47~(\mathrm{stat})\pm0.16~(\mathrm{syst} )~\mathrm{MeV/}c^{2}. \end{equation*

Observation of Bc+→D0K+B_{c}^{+} \rightarrow D^{0} K^{+} decays

Using proton-proton collision data corresponding to an integrated luminosity of 3.0  fb-1, recorded by the LHCb detector at center-of-mass energies of 7 and 8 TeV, the Bc+→D0K+ decay is observed with a statistical significance of 5.1 standard deviations. By normalizing to B+→D¯0π+ decays, a measurement of the branching fraction multiplied by the production rates for Bc+ relative to B+ mesons in the LHCb acceptance is obtained, RD0K=(fc/fu)×B(Bc+→D0K+)=(9.3-2.5+2.8±0.6)×10-7, where the first uncertainty is statistical and the second is systematic. This decay is expected to proceed predominantly through weak annihilation and penguin amplitudes, and is the first Bc+ decay of this nature to be observed.Using proton-proton collision data corresponding to an integrated luminosity of 3.0 fb$^{-1}$, recorded by the LHCb detector at centre-of-mass energies of 7 and 8 TeV, the $B_{c}^{+} \rightarrow D^{0} K^{+}$ decay is observed with a statistical significance of 5.1 standard deviations. By normalising to $B^{+} \rightarrow \bar{D}^{0} \pi^{+}$ decays, a measurement of the branching fraction multiplied by the production rates for $B_{c}^{+}$ relative to $B^{+}$ mesons in the LHCb acceptance is obtained, R_{D^{0} K} = \frac{f_{c}}{f_{u}}\times\mathcal{B}(B_{c}^{+} \rightarrow D^{0} K^{+}) = (9.3\,^{+2.8}_{-2.5} \pm 0.6) \times 10^{-7}\,where the first uncertainty is statistical and the second is systematic. This decay is expected to proceed predominantly through weak annihilation and penguin amplitudes, and is the first $B_{c}^{+}$ decay of this nature to be observed

Measurement of the B±B^{\pm} production asymmetry and the CPCP asymmetry in B±→J/ψK±B^{\pm} \to J/\psi K^{\pm} decays

The B± meson production asymmetry in pp collisions is measured using B+→D¯0π+ decays. The data were recorded by the LHCb experiment during Run 1 of the LHC at center-of-mass energies of s=7 and 8 TeV. The production asymmetries, integrated over transverse momenta in the range 2<pT<30  GeV/c, and rapidities in the range 2.1<y<4.5 are measured to be Aprod(B+,s=7  TeV)=(-0.41±0.49±0.10)×10-2, Aprod(B+,s=8  TeV)=(-0.53±0.31±0.10)×10-2, where the first uncertainties are statistical and the second are systematic. These production asymmetries are used to correct the raw asymmetries of B+→J/ψK+ decays, thus allowing a measurement of the CP asymmetry, ACP(B+→J/ψK+)=(0.09±0.27±0.07)×10-2.The $B^{\pm}$ meson production asymmetry in $pp$ collisions is measured using $B^+ \to \bar{D}^0 \pi^+$ decays. The data were recorded by the LHCb experiment during Run 1 of the LHC at centre-of-mass energies of $\sqrt{s}=$ 7 and 8 TeV. The production asymmetries, integrated over transverse momenta in the range $2 < p_{\rm T} < 30$ GeV/$c$, and rapidities in the range $2.1 < y < 4.5$, are measured to be \begin{align*} \mathcal{A}_{\rm prod}(B^+,\sqrt{s}=7~{\rm TeV}) &= (-0.41 \pm 0.49 \pm 0.10) \times 10^{-2},\\ \mathcal{A}_{\rm prod}(B^+,\sqrt{s}=8~{\rm TeV}) &= (-0.53 \pm 0.31 \pm 0.10) \times 10^{-2}, \end{align*} where the first uncertainties are statistical and the second are systematic. These production asymmetries are used to correct the raw asymmetries of $B^{+} \to J/\psi K^{+}$ decays, thus allowing a measurement of the $CP$ asymmetry, \begin{equation*} \mathcal{A}_{CP} = (0.09 \pm 0.27 \pm 0.07) \times 10^{-2}. \end{equation*

Observation of the decay Bs0→ϕπ+π−B^0_s \to \phi\pi^+\pi^- and evidence for B0→ϕπ+π−B^0 \to \phi\pi^+\pi^-

The first observation of the rare decay Bs0→ϕπ+π- and evidence for B0→ϕπ+π- are reported, using pp collision data recorded by the LHCb detector at center-of-mass energies s=7 and 8 TeV, corresponding to an integrated luminosity of 3  fb-1. The branching fractions in the π+π- invariant mass range 400<m(π+π-)<1600  MeV/c2 are [3.48±0.23±0.17±0.35]×10-6 and [1.82±0.25±0.41±0.14]×10-7 for Bs0→ϕπ+π- and B0→ϕπ+π- respectively, where the uncertainties are statistical, systematic and from the normalization mode Bs0→ϕϕ. A combined analysis of the π+π- mass spectrum and the decay angles of the final-state particles identifies the exclusive decays Bs0→ϕf0(980), Bs0→ϕf2(1270), and Bs0→ϕρ0 with branching fractions of [1.12±0.16-0.08+0.09±0.11]×10-6, [0.61±0.13-0.05+0.12±0.06]×10-6 and [2.7±0.7±0.2±0.2]×10-7, respectively.The first observation of the rare decay$B^0_s \to \phi\pi^+\pi^-$ and evidence for $B^0 \to \phi\pi^+\pi^-$ are reported, using $pp$ collision data recorded by the LHCb detector at centre-of-mass energies $\sqrt{s} = 7$ and 8~TeV, corresponding to an integrated luminosity of 3{\mbox{\,fb}^{-1}}. The branching fractions in the $\pi^+\pi^-$ invariant mass range $400<m(\pi^+\pi^-)<1600{\mathrm{\,Me\kern -0.1em V\!/}c^2}$ are $[3.48\pm 0.23\pm 0.17\pm 0.35]\times 10^{-6}$ and $[1.82\pm 0.25\pm 0.41\pm 0.14]\times 10^{-7}$ for $B^0_s \to \phi\pi^+\pi^-$ and $B^0 \to \phi\pi^+\pi^-$ respectively, where the uncertainties are statistical, systematic and from the normalisation mode $B^0_s \to \phi\phi$. A combined analysis of the $\pi^+\pi^-$ mass spectrum and the decay angles of the final-state particles identifies the exclusive decays $B^0_s \to \phi f_0(980)$, $B_s^0 \to \phi f_2(1270)$, and $B^0_s \to \phi\rho^0$ with branching fractions of $[1.12\pm 0.16^{+0.09}_{-0.08}\pm 0.11]\times 10^{-6}$, $[0.61\pm 0.13^{+0.12}_{-0.05}\pm 0.06]\times 10^{-6}$ and $[2.7\pm 0.7\pm 0.2\pm 0.2]\times 10^{-7}$, respectively

Observation of Bc+→J/ψD(∗)K(∗)B_{c}^{+} \to J/\psi D^{(*)} K^{(*)} decays

A search for the decays Bc+→J/ψD(*)0K+ and Bc+→J/ψD(*)+K*0 is performed with data collected at the LHCb experiment corresponding to an integrated luminosity of 3  fb-1. The decays Bc+→J/ψD0K+ and Bc+→J/ψD*0K+ are observed for the first time, while first evidence is reported for the Bc+→J/ψD*+K*0 and Bc+→J/ψD+K*0 decays. The branching fractions of these decays are determined relative to the Bc+→J/ψπ+ decay. The Bc+ mass is measured, using the J/ψD0K+ final state, to be 6274.28±1.40(stat)±0.32(syst)  MeV/c2. This is the most precise single measurement of the Bc+ mass to date.A search for the decays $B_c^+ \to J/\psi D^{(*)0} K^+$ and $B_c^+ \to J/\psi D^{(*)+} K^{*0}$ is performed with data collected at the LHCb experiment corresponding to an integrated luminosity of 3 fb$^{-1}$. The decays $B_c^+ \to J/\psi D^0 K^+$ and $B_c^+ \to J/\psi D^{*0} K^+$ are observed for the first time, while first evidence is reported for the $B_c^+ \to J/\psi D^{*+} K^{*0}$ and $B_c^+ \to J/\psi D^+ K^{*0}$ decays. The branching fractions of these decays are determined relative to the $B_c^+ \to J/\psi \pi^+$ decay. The $B_c^+$ mass is measured, using the $J/\psi D^0 K^+$ final state, to be $6274.28 \pm 1.40 (stat) \pm 0.32 (syst)$ MeV/$c^2$. This is the most precise single measurement of the $B_c^+$ mass to date