Xi Sigma Pi

Xi Sigma Pi, was founded at the University of Washington on November 24, 1908, and is the oldest and largest national forestry honor fraternity. The Alpha Gamma chapter at Iowa State University was created in 1965

Educating the Interprofessional Team and Family About Sensory Challenges Children with Autism Spectrum Disorder May Experience

Introduction: Children with autism spectrum disorder (ASD) often demonstrate difficulties processing and interpreting sensory input experiencing over-responsiveness or under-responsiveness to sensory stimulation (Autism Speaks, n.d.). A sensory education program was created to educate the interprofessional team and families about sensory challenges children with ASD experience and what strategies can be used to prevent or decrease the number of outbursts caused by over-stimulation, under-stimulation, and their potential impact on participation in meaningful occupations. Based on the literature review, non-compliance with home programs is a major factor negatively affecting therapeutic outcomes (Rone-Adams, Stern, & Walker, 2004). However, Koegel, Bryan, Su, Vaidya, and Camarata (2020) found that outcomes are much greater when caregivers implement interventions throughout the child’s day. Therefore, collaboration with caregivers will be beneficial to help promote compliance of carrying over skills through the sensory education program. Methodology: An extensive literature review was conducted to acquire information to create evidence-based strategies for the interprofessional team and families to use. The author utilized research articles, textbooks, and resources available from reliable databases including CINAHL complete, Google Scholar, and American Occupational Therapy Association (AOTA). The Ecology of Human Performance (EHP) model was used to guide the development of the education program with emphasis on the intervention approaches to develop sensory strategies that will meet the child’s specific needs (Dunn, 2017). Results: The child’s vestibular, proprioceptive, visual, auditory, gustatory, olfactory, and tactile sensations can be highly impacted as the child may experience difficulties processing sensory input (Watling & Hauer, 2015). The sensory education home program provides sensory intervention strategies for caregivers to address children’s sensory needs outside of the occupational therapy environment. The program provides a variety of strategies addressing all sensory systems as every child’s needs differ. Conclusion: It is anticipated that the sensory education program will help to educate the parents and the interprofessional team on a variety of sensory approaches that could be used outside of the occupational therapy environment to facilitate participation in daily routines and occupations

Critically Appraised Topic: Hippotherapy Intervention for School Age Children with Autism Spectrum Disorders

The prevalence of autism spectrum disorders (ASD) has risen nearly 600 percent in the past two decades, with estimates suggesting that 1 in 68 children worldwide have a clinical diagnosis (Centers for Disease Control and Prevention [CDC], 2014). Children with ASD experience resultant challenges in occupational functioning due to impairments in communication, social interaction, and sensory processing. Sensory modulation issues can cause negative impacts on physical and social functioning. Modulation allows filtering of irrelevant stimuli and maintenance of an optimal level of arousal that facilitates attention to environmental demands with longer engagement in tasks (Llambias, Magill-Evans, Smith, & Warren, 2016). Recent literature suggests that occupational therapy has the potential to positively impact children with sensory modulation issues caused by autism spectrum disorder through the use of hippotherapy

General assessment of urban community forestry activities in Iowa 1994 to 1996

Since 1990, there has been an increase in tree planting in Iowa communities largely due to programs sponsored by investor-owned utilities. However, no data are available on the potential impacts of these planting, programs on community forest management in Iowa communities. Objectives of this study were to: (i) measure increases in community forestry activities in Iowa towns after they received utility-based tree-planting funds, and (ii) develop base-line information on types of community forestry management activities occurring in towns between 1994 and 1996. To accomplish these objectives, unique questionnaires were mailed to municipalities and to local tree group volunteers. Total response rate for the two surveys was 60 percent (n=941). Eighty-two percent of the communities responding to the volunteer survey (n= 100) showed an increase in community forestry activities (e.g. volunteer tree planting group, tree board, fund-raising activities, tree inventory) after they received utility-based tree-planting funds, and 40 percent added as many as four new activities. In most cases, the percentage of community respondents in the municipal survey with populations greater than 10,000 people, indicated they had specific forestry management activities more often than respondents from smaller communities. Responding communities to the municipal survey indicated that between 1994 and 1996 at least one tree was being planted for every tree that was being removed from public property. This is the reverse of earlier trends in Iowa. For the communities represented in the volunteer survey, it appears that the existence of structured organization and grass roots support increased the short-term benefits of investor-owned utility tree planting programs. To continue the recent positive trends in Iowa, it will be important for groups like investor-owned utilities and the Iowa Urban and Community Forestry Council to continue their support and encouragement of tree resource management

A Single-Dose Intramuscular Immunization of Pigs with Lipid Nanoparticle DNA Vaccines Based on the Hemagglutinin Antigen Confers Complete Protection against Challenge Infection with the Homologous Influenza Virus Strain

The Influenza A virus of swine (IAV-S) is highly prevalent and causes significant economic losses to swine producers. Due to the highly variable and rapidly evolving nature of the virus, it is critical to develop a safe and versatile vaccine platform that allows for frequent updates of the vaccine immunogens to cope with the emergence of new viral strains. The main objective of this study was to assess the feasibility of using lipid nanoparticles (LNPs) as nanocarriers for delivering DNA plasmid encoding the viral hemagglutinin (HA) gene in pigs. The intramuscular administration of a single dose of the LNP-DNA vaccines resulted in robust systemic and mucosal responses in pigs. Importantly, the vaccinated pigs were fully protected against challenge infection with the homologous IAV-S strain, with only 1 out of 12 vaccinated pigs shedding a low amount of viral genomic RNA in its nasal cavity. No gross or microscopic lesions were observed in the lungs of the vaccinated pigs at necropsy. Thus, the LNP-DNA vaccines are highly effective in protecting pigs against the homologous IAV-S strain and can serve as a promising platform for the rapid development of IAV-S vaccines

Development of septic polysynovitis and uveitis in foals experimentally infected with \u3ci\u3eRhodococcus equi\u3c/i\u3e

Rhodococcus equi is one of the most important causes of disease in foals. Infection is typically characterized by pyogranulomatous pneumonia although extrapulmonary infections occur occasionally. Uveitis and polysynovitis have been reported in foals naturally infected with R. equi and are thought to be the result of an immune-mediated process. However, the pathogenesis of these conditions is poorly understood. The objectives of this study were to document the occurrence of uveitis and polysynovitis after experimental infection with R. equi and to determine if these disorders are the direct result of infection at these sites. Foals between 3 and 4 weeks of age were infected intratracheally with virulent R. equi using inocula of 1×108 CFU (high inoculum; n = 16) or 1×107 CFU (low inoculum; n = 12). Foals were monitored twice daily and necropsy was performed 14 days post-infection. Aqueous humor and synovial fluid were collected aseptically and the percentage of affected lung was calculated. The mean (± SD) percentage of affected lung was significantly higher with the high inoculum (31.8 ± 14.6%) than with the low inoculum (14.4 ± 11.4%). Fourteen of 25 foals developed uveitis and 20 of 28 foals developed polysynovitis. R. equi was cultured from the aqueous humor of 11 foals and from the synovial fluid of 14 foals. The risk of development of polysynovitis and protein concentration in the aqueous humor were significantly higher in foals that received the high inoculum. These results indicate that polysynovitis and uveitis are septic complications associated with the severity of lung disease

Effectiveness of Composting as a Biosecure Disposal Method for Porcine Epidemic Diarrhea Virus (PEDV)-Infected Pig Carcasses

Porcine epidemic diarrhea virus (PEDV) is an enteric disease of swine that has emerged as a worldwide threat to swine herd health and production. Substantial research has been conducted to assess viability of the virus on surfaces of vehicles and equipment, in feed and water, and on production building surfaces, but little is known about the persistence in PEDV-infected carcasses and effective disposal methods thereof. This study was conducted to quantify the persistence of PEDV RNA via quantitative real-time reverse transcription polymerase chain reaction (qRT-PCR) at various time-temperature combinations and in infected piglet carcasses subjected to composting. Although this method does not distinguish between infectious and noninfectious virus, it is a rapid and sensitive test to evaluate materials for evidence of virus genome

A Single Amino Acid Substitution in Porcine Reproductive and Respiratory Syndrome Virus Glycoprotein 2 Significantly Impairs Its Infectivity in Macrophages

Porcine reproductive and respiratory syndrome virus (PRRSV) has a restricted tropism for macrophages and CD163 is a key receptor for infection. In this study, the PRRSV strain NCV1 was passaged on MARC-145 cells for 95 passages, and two plaque-clones (C1 and C2) were randomly selected for further analysis. The C1 virus nearly lost the ability to infect porcine alveolar macrophages (PAMs), as well as porcine kidney cells expressing porcine CD163 (PK15-pCD163), while the C2 virus replicates well in these two cell types. Pretreatment of MARC-145 cells with an anti-CD163 antibody nearly blocked C1 virus infection, indicating that the virus still required CD163 to infect cells. The C1 virus carried four unique amino acid substitutions: three in the nonstructural proteins and a K160I in GP2. The introduction of an I160K substitution in GP2 of the C1 virus restored its infectivity in PAMs and PK15-pCD163 cells, while the introduction of a K160I substitution in GP2 of the low-passaged, virulent PRRSV strain NCV13 significantly impaired its infectivity. Importantly, pigs inoculated with the rNCV13-K160I mutant exhibited lower viremia levels and lung lesions than those infected with the parental rNCV13. These results demonstrated that the K160 residue in GP2 is one of the key determinants of PRRSV tropism

Host Transcriptional Response to Persistent Infection with a Live-Attenuated Porcine Reproductive and Respiratory Syndrome Virus Strain

Both virulent and live-attenuated porcine reproductive and respiratory syndrome virus (PRRSV) strains can establish persistent infection in lymphoid tissues of pigs. To investigate the mechanisms of PRRSV persistence, we performed a transcriptional analysis of inguinal lymphoid tissue collected from pigs experimentally infected with an attenuated PRRSV strain at 46 days post infection. A total of 6404 differentially expressed genes (DEGs) were detected of which 3960 DEGs were upregulated and 2444 DEGs were downregulated. Specifically, genes involved in innate immune responses and chemokines and receptors associated with T-cell homing to lymphoid tissues were down regulated. As a result, homing of virus-specific T-cells to lymphoid tissues seems to be ineffective, evidenced by the lower frequencies of virus-specific T-cell in lymphoid tissue than in peripheral blood. Genes associated with T-cell exhaustion were upregulated. Likewise, genes involved in the anti-apoptotic pathway were upregulated. Collectively, the data suggested that the live-attenuated PRRSV strain establishes a pro-survival microenvironment in lymphoid tissue by suppressing innate immune responses, T-cell homing, and preventing cell apoptosis