943 research outputs found
A Study on Emotional Maturity of College Students
The Emotional maturity becomes important in the behaviour of individuals. As the students are the pillars of the future generations their Emotional maturity is vital one. So the present study intends to measure the Emotional Maturity of college students. Normative survey method and random sampling technique has been used in the present study. The “Emotional Maturity Scale†standardized by K.M.Roma Pal [5] was used for this study. The result of the study shows that the emotional maturity of college students is extremely unstable
Implementation of Mobile Robot Localisation and Path Planning for Navigation in Known Map
This paper describes the implementation of a laser scanner to localise a mobile robot in a known map and navigate to a pinpointed location while avoiding any obstacles within the path. The ability to successfully localise itself is a key requirement for any mobile robot. The Turtlebot Create is used as the platform part to test the localisation. The probabilistic localisation method, the Adaptive Monte Carlo Localization (AMCL) technique is used for the purpose. The approach is experimentation driven due to unique and unanticipated challenges present in the environment. As for obstacle avoidance and path planning, the Dynamic Window Approach (DWA) and Dijkstra’s algorithm is used respectively. The implementation is done using Robot Operating System (ROS) framework and thus is reusable in any future projects with both, simulated and real platforms. The experiments were run in CEASTech and UniMAP Solutions, and it was observed that the robot was able to firstly map the two environments, localise itself in the known map and manoeuvre to the pinpointed locations without any collision
Markers of inflammation and bone remodelling associated with improvement in clinical response measures in psoriatic arthritis patients treated with golimumab
<p>Objective To determine serum biomarker associations with clinical response to golimumab treatment in patients with psoriatic arthritis (PsA).</p>
<p>Methods GO–REVEAL was a randomised, placebo-controlled study of golimumab in patients with active PsA. Samples were collected from 100 patients at baseline, week 4 and week 14, and analysed for serum-based biomarkers and protein profiling (total 92 markers); data were correlated with clinical measures at week 14.</p>
<p>Results Serum levels of a subset of proteins (apolipoprotein C III, ENRAGE, IL-16, myeloperoxidase, vascular endothelial growth factor, pyridinoline, matrix metalloproteinase 3, C-reactive protein (CRP), carcinoembryonic antigen, intercellular adhesion molecule 1 and macrophage inflammatory protein 1α) at baseline or week 4 were strongly associated with American College of Rheumatology 20% improvement (ACR20) response and/or disease activity score in 28 joints (DAS28) at week 14. A smaller subset of proteins was significantly associated with a 75% improvement in the psoriasis area and severity index score (PASI75) at week 14, (adiponectin, apolipoprotein CIII, serum glutamic oxaloacetic transaminase, and tumour necrosis factor α). Subsets of proteins were identified as potentially predictive of clinical response for each of the clinical measures, and the power of these biomarker panels to predict clinical response to golimumab treatment was stronger than for CRP alone.</p>
<p>Conclusions This analysis provides insight into several panels of markers that may have utility in identifying PsA patients likely to have ACR20, DAS28, or PASI75 responses following golimumab treatment.</p>
Comparative effects of glucose and water drinks on blood pressure and cardiac function in older subjects with and without postprandial hypotension
Postprandial hypotension (PPH) occurs frequently and is thought to reflect an inadequate increase in cardiac output to compensate for the rise in splanchnic blood flow after a meal. Gastric distension by water attenuates the postprandial fall in blood pressure (BP). Cardiac hemodynamics (stroke volume (SV), cardiac output (CO), and global longitudinal strain (GLS)) have hitherto not been measured in PPH We sought to determine the comparative effects of water and glucose drinks on cardiac hemodynamics in healthy older subjects and individuals with PPH Eight healthy older subjects (age 71.0 ± 1.7 years) and eight subjects with PPH (age 75.5 ± 1.0 years) consumed a 300 mL drink of either water or 75 g glucose (including 150 mg 13C-acetate) in randomized order. BP and heart rate (HR) were measured using an automatic device, SV, CO, and GLS by transthoracic echocardiography and gastric emptying by measurement of 13CO2 In both groups, glucose decreased systolic BP (P < 0.001) and increased HR, SV, and CO (P < 0.05 for all). The fall in systolic BP was greater (P < 0.05), and increase in HR less (P < 0.05), in the PPH group, with no difference in SV or CO Water increased systolic BP (P < 0.05) in subjects with PPH and, in both groups, decreased HR (P < 0.05) without affecting SV, CO, or GLS In subjects with PPH, the hypotensive response to glucose and the pressor response to water were related (R = -0.75, P < 0.05). These observations indicate that, in PPH, the hypotensive response to oral glucose is associated with inadequate compensatory increases in CO and HR, whereas the pressor response to water ingestion is maintained and, possibly, exaggerated.Laurence G. Trahair, Sharmalar Rajendran, Renuka Visvanathan, Matthew Chapman, Daniel Stadler, Michael Horowitz and Karen L. Jone
Observations of NGC 4151 During 1970 in the Optical and Infra-red
Observations of NGC 4151 at seven wavelengths from 0.3 to 3.4 microns made during the 1970 season are presented. Variations are found at all observed wavelengths but the optical and infra-red light curves are different: an optical maximum was reached in April but the galaxy continued brightening at 2.2 μ . until the end of June. The energy distributions of the point source and the background galaxy have been separated and that of the point source Closely resembles that of the quasar 3C273. The general form of the light curves can possibly be attributed to a dust model for the infra-red emission but this would be ruled out if suspected rapid infra-red variations are confirmed
Observations of NGC 4151 During 1970 in the Optical and Infra-red
Observations of NGC 4151 at seven wavelengths from 0.3 to 3.4 microns made during the 1970 season are presented. Variations are found at all observed wavelengths but the optical and infra-red light curves are different: an optical maximum was reached in April but the galaxy continued brightening at 2.2 μ . until the end of June. The energy distributions of the point source and the background galaxy have been separated and that of the point source Closely resembles that of the quasar 3C273. The general form of the light curves can possibly be attributed to a dust model for the infra-red emission but this would be ruled out if suspected rapid infra-red variations are confirmed
Clinical screening tools for sarcopenia and Its management
Sarcopenia, an age-related decline in muscle mass and function, is affecting the older population worldwide. Sarcopenia is associated with poor health outcomes, such as falls, disability, loss of independence, and mortality; however it is potentially treatable if recognized and intervened early. Over the last two decades, there has been significant expansion of research in this area. Currently there is international recognition of a need to identify the condition early for intervention and prevention of the disastrous consequences of sarcopenia if left untreated. There are currently various screening tools proposed. As yet, there is no consensus on the best tool. Effective interventions of sarcopenia include physical exercise and nutrition supplementation. This review paper examined the screening tools and interventions for sarcopenia.Solomon C.Y. Yu, Kareeann S.F. Khow, Agathe D. Jadczak and Renuka Visvanatha
The Red-Sequence Luminosity Function in Galaxy Clusters since z~1
We use a statistical sample of ~500 rich clusters taken from 72 square
degrees of the Red-Sequence Cluster Survey (RCS-1) to study the evolution of
~30,000 red-sequence galaxies in clusters over the redshift range 0.35<z<0.95.
We construct red-sequence luminosity functions (RSLFs) for a well-defined,
homogeneously selected, richness limited sample. The RSLF at higher redshifts
shows a deficit of faint red galaxies (to M_V=> -19.7) with their numbers
increasing towards the present epoch. This is consistent with the `down-sizing`
picture in which star-formation ended at earlier times for the most massive
(luminous) galaxies and more recently for less massive (fainter) galaxies. We
observe a richness dependence to the down-sizing effect in the sense that, at a
given redshift, the drop-off of faint red galaxies is greater for poorer (less
massive) clusters, suggesting that star-formation ended earlier for galaxies in
more massive clusters. The decrease in faint red-sequence galaxies is
accompanied by an increase in faint blue galaxies, implying that the process
responsible for this evolution of faint galaxies is the termination of
star-formation, possibly with little or no need for merging. At the bright end,
we also see an increase in the number of blue galaxies with increasing
redshift, suggesting that termination of star-formation in higher mass galaxies
may also be an important formation mechanism for higher mass ellipticals. By
comparing with a low-redshift Abell Cluster sample, we find that the
down-sizing trend seen within RCS-1 has continued to the local universe.Comment: ApJ accepted. 11 pages, 5 figure
The Hubble Space Telescope Key Project on the Extragalactic Distance Scale XXIV: The Calibration of Tully-Fisher Relations and the Value of the Hubble Constant
This paper presents the calibration of BVRIH$ Tully-Fisher relations based on
Cepheid distances to 21 galaxies within 25 Mpc, and 23 clusters within 10,000
km/s. These relations have been applied to several distant cluster surveys in
order to derive a value for the Hubble constant, H0, mainly concentrating on an
I-band all-sky survey by Giovanelli and collaborators which consisted of total
I magnitudes and 50% linewidth data for ~550 galaxies in 16 clusters. For
comparison, we also derive the values of H0 using surveys in B-band and V-band
by Bothun and collaborators, and in H-band by Aaronson and collaborators.
Careful comparisons with various other databases from literature suggest that
the H-band data, whose magnitudes are isophotal magnitudes extrapolated from
aperture magnitudes rather than total magnitudes, are subject to systematic
uncertainties. Taking a weighted average of the estimates of Hubble constants
from four surveys, we obtain H0 = 71 +- 4 (random) +- 7 (systematic) km/s/Mpc.
We have also investigated how various systematic uncertainties affect the value
of H0 such as the internal extinction correction method used, Tully-Fisher
slopes and shapes, a possible metallicity dependence of the Cepheid
period-luminosity relation and cluster population incompleteness bias.Comment: 34 pages, 13 figure
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