108 research outputs found
Invasive carcinomas of the male breast: a morphologic study of the distribution of histologic subtypes and metastatic patterns in 778 cases
The current investigation was conducted to evaluate the proportional distribution of the various histologic subtypes (including newly recognized variants) of male breast carcinomas, to determine whether any histologic subtypes occur with a frequency that is markedly discordant with the expected frequencies from published data on parallel female breast tumors. We also aimed to document the distribution of malignancies metastatic to the breast. Seven hundred fifty-nine archived cases of primary invasive carcinoma involving the male breast were retrieved and subcategorized into histologic subtypes according to contemporary criteria. Six hundred forty-three (84.7%) tumors were pure infiltrating ductal carcinoma (IDC) not otherwise specified. The most common of the remainder included papillary carcinoma with invasion in the form of IDC (n = 34), mixed IDC and mucinous carcinoma (n = 26), and pure mucinous carcinoma (n = 21). In 19 cases, metastases from other sites involved the breast, most commonly (58%) cutaneous melanoma. Invasive carcinoma of the male breast appears to display a morphologic spectrum and distribution of histologic subtypes that is comparable to those of the female breast, with some expected variation. Compared with published experience on their female counterparts, there is a two-fold increase in the frequency of invasive papillary carcinoma in the male breast. Finally, the most common tumor metastatic to the male breast in this series was cutaneous melanoma
Radiation-Induced Chromosome Aberrations:Persisting Aberrations in Long-Term Cultures from Human Skin Irradiated in vivo
Aldersfordelingen af hospitalsobducerede 1977-1996. Der obduceres nu forholdsvis flere unge siden indførelsen af den nye ligsynslov af 1990
The Syndrome of Jaw Cysts - Basal Cell Carcinomas - Skeletal Anomalies:CLINICAL STUDY WITH CHROMOSOMAL ANALYSES OF A FAMILY
LIMITATIONS OF CHROMOSOME ANALYSIS AS A METHOD FOR BIOLOGICAL DOSIMETRY OF CHRONIC EXTERNAL RADIATION AND OF INTERNAL EXPOSURE TO THERAPEUTIC RADIOPHOSPHORUS
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