Variability in fractional anisotropy measurements.

<p>Box and whisker plot for fractional anisotropy values (mm²/second) for the white matter region of interest (ROI) measurements. The spread of data within each ROI reflects inter subject variation, while the difference between runs 1–2 and 3–4 reflects within session reproducibility, and the change from first to second sessions reflects between session reproducibility. The central lines in each box denote median values, the lower and upper boundaries the 25th and 75th centile, the error bars the 10th and 90th centile, and the closed circles outlying data points. Anterior corpus callosum (ACC), body corpus callosum (BCC), posterior corpus callosum (PCC), left anterior thalamic radiation (ATR L), right anterior thalamic radiation (ATR R), left superior longitudinal fasciculus (SLF L), right superior longitudinal fasciculus (SLF R), left inferior longitudinal fasciculus (ILF L), right inferior longitudinal fasciculus (ILF R), left cingulum (Cingulum L), right cingulum (Cingulum R), left uncinate fasciculus (UFL), right uncinate fasciculus (UFR), left corticospinal tract (CST L), right corticospinal tract (CST R), dorsal midbrain (dorsal MB), ventral midbrain (ventral midbrain), left cerebral peduncle (CP L), right cerebral peduncle (CP R), left pons (pons L) and right pons (pons R).</p

Within and between session variability of diffusion tensor imaging region of interest measurements.

<p>Individual white matter region of interest measurements for within session reproducibility obtained in the first and second imaging sessions in 26 and 22 subjects respectively, and the between session reproducibility for those 22 subjects who underwent imaging at both sessions. Data displayed are standard deviation of measurements for fractional anisotropy (FA), apparent diffusion coefficient (ADC), axial (AD) and radial (RD) diffusivity.</p

Intersubject variability for diffusion tensor imaging measurements for predominantly white matter regions of interest (ROI).

<p>Intersubject variability for Fractional anisotropy (FA), apparent diffusion coefficient (ADC), axial and radial diffusivity. Data displayed were obtained in 26 subjects and show mean, standard deviation (SD) and coefficient of variation (CoV).</p

Within and between session variability of diffusion tensor imaging region of interest measurements.

<p>Individual mixed cortical and deep grey region of interest measurements for within session reproducibility obtained in the first and second imaging sessions in 26 and 22 subjects respectively, and the between session reproducibility for those 22 subjects who underwent imaging at both sessions. Data displayed are percentage coefficient of variation of measurements for fractional anisotropy (FA), apparent diffusion coefficient (ADC), axial (AD) and radial (RD) diffusivity.</p

Analysis of variance table for diffusion tensor imaging parameters.

<p>Data (mm²/second) were obtained from 26 volunteers using the region of interest (ROI) template for fractional anisotropy (FA), apparent diffusion coefficient (ADC), axial diffusivity (AD), and radial diffusivity (RD). Degrees of freedom (DF).</p

Intersubject variability for diffusion tensor imaging measurements for mixed cortical and deep grey matter regions of interest (ROI).

<p>Intersubject variability for Fractional anisotropy (FA), apparent diffusion coefficient (ADC), axial and radial diffusivity. Data displayed were obtained in 26 subjects and show mean, standard deviation (SD) and coefficient of variation (CoV).</p

Within and between session variability of diffusion tensor imaging region of interest measurements.

<p>Individual mixed cortical and deep grey matter region of interest measurements for within session reproducibility obtained in the first and second imaging sessions in 26 and 22 subjects respectively, and the between session reproducibility for those 22 subjects who underwent imaging at both sessions. Data displayed are standard deviation of measurements for fractional anisotropy (FA), apparent diffusion coefficient (ADC), axial (AD) and radial (RD) diffusivity.</p

Region of interest template.

<p>T1 weighted magnetic resonance image in MNI152 space (2 mm resolution) showing frontal lobe left (Frontal L), frontal lobe right (Frontal R), anterior corpus callosum (ACC), caudate left (Caudate L), caudate right (Caudate R), thalamus left (Thalamus L), thalamus right (Thalamus R), posterior corpus callosum (PCC), occipital left (Occipital L) and occipital right (Occipital R). Additional regions not shown include body corpus callosum, ventral midbrain, dorsal midbrain, forceps minor, forceps major and bilateral regions covering the hippocampus, parietal lobe, temporal lobe, cerebral peduncle, pons, cerebellum, anterior thalamic radiation, superior longitudinal fasciculus, inferior longitudinal fasciculus, cingulum, uncinate fasciculus and corticospinal tract.</p

Within and between session variability of diffusion tensor imaging region of interest measurements.

<p>Individual white matter region of interest measurements for within session reproducibility obtained in the first and second imaging sessions in 26 and 22 subjects respectively, and the between session reproducibility for those 22 subjects who underwent imaging at both sessions. Data displayed are percentage coefficient of variation of measurements for fractional anisotropy (FA), apparent diffusion coefficient (ADC), axial (AD) and radial (RD) diffusivity.</p