Situaţia epidemiologică şi realizarea programului naţional de control şi profilaxie a tuberculozei pentru anii 2006-2010 în Republica Moldova

Programul Naţional de Control şi Profi laxie a Tuberculozei pentru anii 2006-2010 (PNCPT) a fost elaborat în baza analizei situaţiei epidemiologice, susţinut tehnic şi fi nanciar de către Programul TB/SIDA, fi nanţat de către Fondul Global de combatere a SIDA, Tuberculozei şi Malariei, Banca Mondială în Republica Moldova şi Fundaţia “Caritaş Luxemburg”. Pentru obţinerea obiectivelor preconizate, au fost realizate strategiile prioritare identifi cate şi incluse în Program menite să orienteze activitatea naţională multisectorială privind controlul tuberculozei pentru perioada anilor 2006-2010

Research and Science Today No.3

Research and Science Today Journal is a publication founded in 2011 and it is dedicated to the students of all levels (license, master and doctoral) of faculties in the country and abroad. We want to offer the participants the opportunity to present their scientific works in the following areas: Social Sciences, Economic Sciences, Legal Sciences, Humanities, Education Sciences, Engineering, Medicine and Sport. This journal provides students the opportunity to create and / or to improve their abilities to write scientific papers. So each appearance (two appearances per year at which we can add supplements) contains a number of papers written by students, masters and doctoral from the faculties from the country or / and abroad. The journal promotes original studies contributing to the progress of knowledge and it is motivated by the need to address issues of theory and practice in the areas mentioned above. The Journal is a training means of the factors involved in the conceptualization, development, implementation and evaluation , aiming the formation of creative personalities who could be able to adapt through the changing conditions of life. Journal wants to be a forum for debates disciplinaries and interdisciplinaries theoretical topics, to become a research support, to leverage this work at regional, national and international levels. We believe that this gathering will enjoy the support from both parts of the researchers and of the practitioners, and will provide appropriate training sources held professional through the current problems

Research and Science Today No.3

Research and Science Today Journal is a publication founded in 2011 and it is dedicated to the students of all levels (license, master and doctoral) of faculties in the country and abroad. We want to offer the participants the opportunity to present their scientific works in the following areas: Social Sciences, Economic Sciences, Legal Sciences, Humanities, Education Sciences, Engineering, Medicine and Sport. This journal provides students the opportunity to create and / or to improve their abilities to write scientific papers. So each appearance (two appearances per year at which we can add supplements) contains a number of papers written by students, masters and doctoral from the faculties from the country or / and abroad. The journal promotes original studies contributing to the progress of knowledge and it is motivated by the need to address issues of theory and practice in the areas mentioned above. The Journal is a training means of the factors involved in the conceptualization, development, implementation and evaluation , aiming the formation of creative personalities who could be able to adapt through the changing conditions of life. Journal wants to be a forum for debates disciplinaries and interdisciplinaries theoretical topics, to become a research support, to leverage this work at regional, national and international levels. We believe that this gathering will enjoy the support from both parts of the researchers and of the practitioners, and will provide appropriate training sources held professional through the current problems

THE INTERACTIVE DIGITAL MAP - A MODERN APPROACH FOR ARCHAEOLOGICAL HERITAGE MANAGEMENT

The paper presents one of the main products of the ArchTerr project “Integrated management of archaeological heritage: archaeological map and administrative procedures for heritage research and protection”. The project is funded by UEFISCDI following the collaboration of two scientific research centers, “Dunărea de Jos” University of Galați and “Politehnica” University of Bucharest.The aim of this scientific paper is to present the main product of the above mentioned project, the interactive digital map of the historical archaeological heritage with geospatial information (Geographic Information Systems GIS).The paper presents the national context that generated the need to develop such a computer application, some European archaeological heritage records models that could be used as examples to follow and the achievements in this field in Romania. The new functionalities introduced by the interactive digital map developed within the ArchTerr project are: polygonal representation of any archeological site surface, representation of its protection area (when the site is also a historical monument), representation of researched areas using preventive archaeological methods, the representation of the archaeological discharged areas inside a site (following the preventive archaeological research). Regarding the efforts to protect the archaeological heritage, we mention the daily activity usefulness of this map for a wide range of users: county directorates for culture; urban planning services (within city halls and county councils); cadastral offices; real estate agencies; any person who intend to ask for a building permit inside an archaeological heritage protected area.At www.archterr.ro it could be found the fully functional interactive digital map.</p

Intex Tests Performed on Hydro Unit no2 from HPP Ruieni before and after Refurbishment

The paper work presents the results of index tests performed on HPP Ruieni hydro unit no 2 before and after refurbishment, using for discharge measurements the Winter-Kennedy method

A Comprehensive Instrument to Measure Teachers&rsquo; Attitude towards Quality Management in the Context of Online Education

The purpose of this study is to elaborate and validate a scale for the evaluation of the teachers&rsquo; attitude towards quality management, by integrating elements of online education. Nine hundred and forty-two teachers from Romania have participated in the study. The exploratory factor analysis has led to the identification of three main dimensions of the scale: (1) communication and alignment; (2) needs and opportunities; and (3) training and support. Teachers participating in managing positions or in quality assurance boards indicated a more positive attitude towards the three components. Furthermore, teachers of a higher teaching experience reported higher values in the needs and opportunities component. The results are useful to educational institutions, program designers and policy makers to evaluate the teachers&rsquo; attitude towards quality management

Inflammatory Status Assessment by Machine Learning Techniques to Predict Outcomes in Patients with Symptomatic Aortic Stenosis Treated by Transcatheter Aortic Valve Replacement

(1) Background: Although transcatheter aortic valve replacement (TAVR) significantly improves long-term outcomes of symptomatic severe aortic stenosis (AS) patients, long-term mortality rates are still high. The aim of our study was to identify potential inflammatory biomarkers with predictive capacity for post-TAVR adverse events from a wide panel of routine biomarkers by employing ML techniques. (2) Methods: All patients diagnosed with symptomatic severe AS and treated by TAVR since January 2016 in a tertiary center were included in the present study. Three separate analyses were performed: (a) using only inflammatory biomarkers, (b) using inflammatory biomarkers, age, creatinine, and left ventricular ejection fraction (LVEF), and (c) using all collected parameters. (3) Results: A total of 338 patients were included in the study, of which 56 (16.5%) patients died during follow-up. Inflammatory biomarkers assessed using ML techniques have predictive value for adverse events post-TAVR with an AUC-ROC of 0.743 and an AUC-PR of 0.329; most important variables were CRP, WBC count and Neu/Lym ratio. When adding age, creatinine and LVEF to inflammatory panel, the ML performance increased to an AUC-ROC of 0.860 and an AUC-PR of 0.574; even though LVEF was the most important predictor, inflammatory parameters retained their value. When using the entire dataset (inflammatory parameters and complete patient characteristics), the ML performance was the highest with an AUC-ROC of 0.916 and an AUC-PR of 0.676; in this setting, the CRP and Neu/Lym ratio were also among the most important predictors of events. (4) Conclusions: ML models identified the CRP, Neu/Lym ratio, WBC count and fibrinogen as important variables for adverse events post-TAVR

Synthesis, Purity Check, Hydrolysis and Removal of <i>o</i>-Chlorobenzyliden Malononitrile (CBM) by Biological Selective Media

The removal yield of organic substances present in water depends on the environmental conditions, on the chemical composition of the water and on the chemical substance dissolved in the water, which constitutes the substrate of the metabolic activities of the microalgae that use these substances in the biochemical reactions of cellular enzyme complexes. o-Chlorobenzylidene malononitrile (CS, to use its military designation) was synthesized in-house, for research purposes, by a condensing reaction between o-chlorobenzaldehide and malononitrilein the presence of diethylamine. The detection, identification and confirmation of o-chlorobenzylidenemalononitrile (coded CBM in this experimental study) was performed using gas chromatography–mass spectrometry (GC-MS) and the purity of CBM was 99%. The biodegradation capacity in the samples that contained the biological suspension, after 24 h and 96 h of incubation, was determined via GC-MS analysis, and no evidence of the presence of CBM or some metabolites of CBM was detected. In the parallel samples, a hydrolysis process of CBM at room temperature, without biological treatment, revealed two main metabolites, malononitrile and o-chlorobenzaldehyde, respectively. This study is focused on evaluating the biodegradation capacity of o-chlorobenzylidene malononitrile in the presence of a biological material, culture of Chlorella sp., in comparison with a classical hydrolysis process. The tests performed indicate that the suspension of Chlorella sp. consumed the entire amount of CBM and metabolites from the analyzed samples. The tests prove that the biological material can be used to decontaminate the affected areas