806 research outputs found

    The Evolution and Climate of the Greenland Ice Sheet as seen in Ice Core δ18O

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    第3回極域科学シンポジウム 横断セッション「海・陸・氷床から探る後期新生代の南極寒冷圏環境変動」11月26日(月) 国立国語研究所 2階講

    Challenges in modelling dissolved organic matter dynamics in agricultural soil using DAISY

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    Because dissolved organic matter (DOM) plays an important role is terrestrial C-,N-and P-balances and transport of these three components to aquatic environments, there is a need to include it in models. This paper presents the concept of the newly developed DOM modules implemented in the DAISY model with focus on the quantification of DOM sorption/desorption and microbial-driven DOM turnover. The kinetics of DOM sorption/desorption is described by the deviation of the actual DOM concentration in solution from the equilibrium concentration, Ceq. The Ceq is soil specific and estimated from pedotransfer functions taking into account the soil content of organic matter, Al and Fe oxides. The turnover of several organic matter pools including one DOM pool are described by first-order kinetics. The DOM module was tested at field scale for three soil treatments applied after cultivating grass–clover swards. Suction cups were installed at depths 30, 60 and 90 cm and soil solution was sampled for quantification of dissolved organic C (DOC) and dissolved organic N (DON). In the topsoil, the observed fluctuations in DOC were successfully simulated when the sorption/desorption rate coefficient k was low. In the subsoil, the observed concentrations of DOC were steadier and the best simulations were obtained using a high k. The model shows that DOC and DON concentrations are levelled out in the subsoils due to soil buffering. The steady concentration levels were based on the Ceq for each horizon and the kinetic concept for sorption/desorption of DOC appeared aviable approach. If Ceq was successfully estimated by the pedotransfer function it was possible to simulate the DOC concentration in the subsoil. In spite of difficulties in describing the DOC dynamics of the topsoil, the DOM module simulates the subsoil concentration level of DOC well, and also — but with more uncertainty — the DON concentration level

    Molecular diffusion of stable water isotopes in polar firn as a proxy for past temperatures

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    Polar precipitation archived in ice caps contains information on past temperature conditions. Such information can be retrieved by measuring the water isotopic signals of δ18O\delta{}^{18}\mathrm{O} and δD\delta\mathrm{D} in ice cores. These signals have been attenuated during densification due to molecular diffusion in the firn column, where the magnitude of the diffusion is isotopologoue specific and temperature dependent. By utilizing the differential diffusion signal, dual isotope measurements of δ18O\delta{}^{18}\mathrm{O} and δD\delta\mathrm{D} enable multiple temperature reconstruction techniques. This study assesses how well six different methods can be used to reconstruct past surface temperatures from the diffusion-based temperature proxies. Two of the methods are based on the single diffusion lengths of δ18O\delta{}^{18}\mathrm{O} and δD\delta\mathrm{D}, three of the methods employ the differential diffusion signal, while the last uses the ratio between the single diffusion lengths. All techniques are tested on synthetic data in order to evaluate their accuracy and precision. We perform a benchmark test to thirteen high resolution Holocene data sets from Greenland and Antarctica, which represent a broad range of mean annual surface temperatures and accumulation rates. Based on the benchmark test, we comment on the accuracy and precision of the methods. Both the benchmark test and the synthetic data test demonstrate that the most precise reconstructions are obtained when using the single isotope diffusion lengths, with precisions of approximately 1.0\,^\mathrm{o}\mathrm{C}. In the benchmark test, the single isotope diffusion lengths are also found to reconstruct consistent temperatures with a root-mean-square-deviation of 0.7\,^\mathrm{o}\mathrm{C}

    Greenland during the last interglacial:the relative importance of insolation and oceanic changes

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    Insolation changes during the Eemian (the last interglacial period, 129 000–116 000 years before present) resulted in warmer than present conditions in the Arctic region. The NEEM ice core record suggests warming of 8 ± 4 K in northwestern Greenland based on stable water isotopes. Here we use general circulation model experiments to investigate the causes of the Eemian warming in Greenland. Simulations of the atmospheric response to combinations of Eemian insolation and preindustrial oceanic conditions and vice versa are used to disentangle the impacts of the insolation change and the related changes in sea surface temperatures and sea ice conditions. The changed oceanic conditions cause warming throughout the year, prolonging the impact of the summertime insolation increase. Consequently, the oceanic conditions cause an annual mean warming of 2 K at the NEEM site, whereas the insolation alone causes an insignificant change. Taking the precipitation changes into account, however, the insolation and oceanic changes cause more comparable increases in the precipitation-weighted temperature, implying that both contributions are important for the ice core record at the NEEM site. The simulated Eemian precipitation-weighted warming of 2.4 K at the NEEM site is low compared to the ice core reconstruction, partially due to missing feedbacks related to ice sheet changes and an extensive sea ice cover. Surface mass balance calculations with an energy balance model further indicate that the combination of temperature and precipitation anomalies leads to potential mass loss in the north and southwestern parts of the ice sheet. The oceanic conditions favor increased accumulation in the southeast, while the insolation appears to be the dominant cause of the expected ice sheet reduction. Consequently, the Eemian is not a suitable analogue for future ice sheet changes

    Clinical characteristics associated with relapse 2 years after electroconvulsive therapy for major depression

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    Objective: High relapse rates are observed after electroconvulsive therapy (ECT) for major depression. Identifying patients who are at increased risk for relapse to intensify their treatment regimen post-ECT might reduce relapse rates. We aimed to determine clinical characteristics that are associated with relapse within 2 years after successful ECT. Methods: Patients who remitted to ECT in a randomised controlled trial comparing adjuvant nortriptyline and placebo during a course of bilateral ECT were followed-up prospectively for 1 year with open-label nortriptyline (Dutch Trial Register NTR5579). Second-year follow-up data were collected retrospectively. Thirty-four patients were included in this follow-up cohort. To examine the association between clinical characteristics and the risk of relapse, unadjusted hazard ratios (HRs) were calculated. Results: At 2 years post-ECT, the overall relapse rate was 50%, and the HRs for relapse in patients with psychotic features, a higher severity of depression, and medication resistance prior to ECT were 0.33 (CI 0.12–0.89; p = 0.029), 0.88 (CI 0.80–0.98; p = 0.014), and 4.48 (CI 1.28–15.73, p = 0.019), respectively. No effect was found for age, sex or episode duration on the relapse rate. Conclusions: Depressed patients with psychotic features, with higher symptom severity and without medication resistance prior to ECT have a significantly decreased risk of relapse after successful ECT. A sustained remission rate of 50% over 2 years in patients with severe major depression who were treated with nortriptyline monotherapy after successful ECT is encouraging.</p

    Use of tiling array data and RNA secondary structure predictions to identify noncoding RNA genes

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    <p>Abstract</p> <p>Background</p> <p>Within the last decade a large number of noncoding RNA genes have been identified, but this may only be the tip of the iceberg. Using comparative genomics a large number of sequences that have signals concordant with conserved RNA secondary structures have been discovered in the human genome. Moreover, genome wide transcription profiling with tiling arrays indicate that the majority of the genome is transcribed.</p> <p>Results</p> <p>We have combined tiling array data with genome wide structural RNA predictions to search for novel noncoding and structural RNA genes that are expressed in the human neuroblastoma cell line SK-N-AS. Using this strategy, we identify thousands of human candidate RNA genes. To further verify the expression of these genes, we focused on candidate genes that had a stable hairpin structures or a high level of covariance. Using northern blotting, we verify the expression of 2 out of 3 of the hairpin structures and 3 out of 9 high covariance structures in SK-N-AS cells.</p> <p>Conclusion</p> <p>Our results demonstrate that many human noncoding, structured and conserved RNA genes remain to be discovered and that tissue specific tiling array data can be used in combination with computational predictions of sequences encoding structural RNAs to improve the search for such genes.</p

    Molecfit: A general tool for telluric absorption correction. I. Method and application to ESO instruments

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    Context: The interaction of the light from astronomical objects with the constituents of the Earth's atmosphere leads to the formation of telluric absorption lines in ground-based collected spectra. Correcting for these lines, mostly affecting the red and infrared region of the spectrum, usually relies on observations of specific stars obtained close in time and airmass to the science targets, therefore using precious observing time. Aims: We present molecfit, a tool for correcting for telluric absorption lines based on synthetic modelling of the Earth's atmospheric transmission. Molecfit is versatile and can be used with data obtained with various ground-based telescopes and instruments. Methods: Molecfit combines a publicly available radiative transfer code, a molecular line database, atmospheric profiles, and various kernels to model the instrument line spread function. The atmospheric profiles are created by merging a standard atmospheric profile representative of a given observatory's climate, of local meteorological data, and of dynamically retrieved altitude profiles for temperature, pressure, and humidity. We discuss the various ingredients of the method, its applicability, and its limitations. We also show examples of telluric line correction on spectra obtained with a suite of ESO Very Large Telescope (VLT) instruments. Results: Compared to previous similar tools, molecfit takes the best results for temperature, pressure, and humidity in the atmosphere above the observatory into account. As a result, the standard deviation of the residuals after correction of unsaturated telluric lines is frequently better than 2% of the continuum. Conclusion: Molecfit is able to accurately model and correct for telluric lines over a broad range of wavelengths and spectral resolutions. (Abridged)Comment: 18 pages, 13 figures, 5 tables, accepted for publication in Astronomy and Astrophysic
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