Stanzaic Forms in Evenki Poetry (the Example of V. Lebedev`s Works) as a Result of Educational Practice

The article studies the characteristics of poetry of the Evens – indigenous peoples of the North, Siberia and the Far East. Relying on Russian literature, the author examines the features of stanzas in the work of poets of the Evens. V. Lebedev`s works are analyzed as poetry examples of a representative of the Evens.В статье исследуются особенности поэзии эвенов – коренных малочисленных народов Севера, Сибири и дальнего Востока. Опираясь на российское литературоведение, автор рассматривает особенности строфики в творчестве эвенских поэтов. В качестве репрезентанта эвенской поэзии анализируется творчество В.д. Лебедева

Bulk-sensitive Photoemission of Mn5Si3

We have carried out a bulk-sensitive high-resolution photoemission experiment on Mn5Si3. The measurements are performed for both core level and valence band states. The Mn core level spectra are deconvoluted into two components corresponding to different crystallographic sites. The asymmetry of each component is of noticeable magnitude. In contrast, the Si 2p spectrum shows a simple Lorentzian shape with low asymmetry. The peaks of the valence band spectrum correspond well to the peak positions predicted by the former band calculation.Comment: To be published in: Solid State Communication

Application of higher harmonics in protection against single-phase earth faults in resonant grounded cable networks of medium voltage

Protections based by higher harmonics absolute measurements the zero sequence currents of the protected object connections against single-phase earth faults in resonant grounded cable networks of medium voltage industrial and urban energy supply systems have been widely applied in Russia since the late 60s of the 20th century. However, some operational problems connected with sufficient selectivity and sensitivity of these protection devices appeared with time. Sensitivity and selectivity of this protection are considerably determined by the instability degree of the higher harmonics total level in single-phase earth fault current of the protected network. Well-known Russian expert Kiskachi V.M. gave approximate estimate of the higher harmonics instability degree at the end of the 60s. Nowadays due to load changes in the main substations load in resonant grounded cable networks of medium voltage higher harmonics fluctuations in single-phase to earth fault current. The simulation models of this networks application and the accumulated experimental data about real networks allow to specify the existing estimates of higher harmonics instability in single-phase to earth fault current and their applicability conditions

Oriented antibody immobilization to polystyrene macrocarriers for immunoassay modified with hydrazide derivatives of poly(meth)acrylic acid

BACKGROUND: Hydrophobic polystyrene is the most common material for solid phase immunoassay. Proteins are immobilized on polystyrene by passive adsorption, which often causes considerable denaturation. Biological macromolecules were found to better retain their functional activity when immobilized on hydrophilic materials. Polyacrylamide is a common material for solid-phase carriers of biological macromolecules, including immunoreagents used in affinity chromatography. New macroformats for immunoassay modified with activated polyacrylamide derivatives seem to be promising. RESULTS: New polymeric matrices for immunoassay in the form of 0.63-cm balls which contain hydrazide functional groups on hydrophilic polymer spacer arms at their surface shell are synthesized by modification of aldehyde-containing polystyrene balls with hydrazide derivatives of poly(meth)acrylic acid. The beads contain up to 0.31 μmol/cm(2) active hydrazide groups accessible for covalent reaction with periodate-oxidized antibodies. The matrices obtained allow carrying out the oriented antibody immobilization, which increases the functional activity of immunosorbents. CONCLUSIONS: An efficient site-directed antibody immobilization on a macrosupport is realized. The polymer hydrophilic spacer arms are the most convenient and effective tools for oriented antibody coupling with molded materials. The suggested scheme can be used for the modification of any other solid supports containing electrophilic groups reacting with hydrazides

Selective complex single-phase earth fault protection for distribution medium-voltage networks

This article deals with selective protection against single-phase earth faults at 6 – 10 kV electrical networks. Different kinds of earth faults, factors influencing the implementation of protection, various principles of protection implementation, are described. Requirements and structure of complex protection applicable to networks with any neutral grounding mode and providing separation of various kinds of earth faults are given in this text

Microstructural evolution of layered K-doped RuCl₃ during annealing traced by thermogravimetric analysis and 3D electron diffraction

Nanoscale phase separation was induced in the K-doped RuCl3 van der Waals material by annealing, and studied with the goal to find a natural design strategy for the formation of two-dimensional architectures as an alternative to the costly and time-consuming experimental artificial growth methods. Phase conversion was traced by means of thermogravimetric analysis combined with mass spectrometry. The local crystal structure of co-existing K3Ru2Cl9 domains with the sizes of about 100 nm was solved by 3D electron diffraction.</p

T35 Epigenetic changes in human cervical carcinomas associated with viral induced pathogenesis

Epigenetics investigates mechanisms that control inheritance of gene expression program during somatic cell divisions. These mechanisms include regulation by DNA methylation, histone post-translational modifications and nucleosome positioning, functioning of regulatory non-coding RNAs, control of alternative splicing of mRNA precursors and high-order chromatin organization. Genome-wide loss of epigenetic stability and increased epigenetic plasticity are common features of all tumor types. In normal tissues epigenetic plasticity allow cells to response on environment signals. Thus, in tumor cells its constitutive activation leads to epigenetic heterogeneity that are the additional hallmark of the most of the classical cancers. Cervical cancers are one of the most interesting models for the analysis of the role of epigenetic changes in tumor progression. These types of tumors are associated with infection of human papilloma viruses of so-called high-risk group (HR-HPV) and characterized by well-defined stages of malignant conversion from intraepithelial neoplasias to carcinomas. The viral DNA can persist in episomal form or integrates into the host-cell genome.Cellular genomes encode genetic information in their linear sequence, but appropriate gene expression requires chromosomes to fold into dynamic complex three-dimensional structures. Scaffold/matrix attachment regions (S/MARs) are specialized genomic DNA sequences that take part in organization of these structures. We demonstrated that methylation of S/MARs was required for their attachment to nuclear matrix and that methylation status of S/MARs was changed in cervical cancer cell compared to normal cells.DNA methylation plays an important role in the regulation of gene expression. We found that methylation of the regulatory sequences in the HPV16 genome specifically changes in transformed compared to the normal cervical epithelial cells. Next, we showed that methylation of the transcription factor binding sites modulates the viral oncogene expression. These data suggest that the HPV16 genome methylation may represent an important mechanism that initiates the development of HPV-associated tumors.Using next generation sequencing, we identified pattern of differentially expressed microRNAs in clinical samples of the cervical lesions. We confirmed expression of microRNAs that have been described previously as well as identified new microRNAs that can be potentially involved in the development and progression of cervical cancer. Spectrum of differentially expressed microRNAs includes microRNAs targeting tumor-suppressor genes as well as oncogenes.Telomerase is a key regulator of cell proliferation. This enzyme is silent in normal cells and activated in most of the tumors. Few forms of RNA (hTERT), encoded by telomerase gene were detected in different tumor cells and among them three forms (alfa, beta and gamma) are most well pronounced. We found that in cervical tumors expression of all three forms are significantly increased. In some cases, we also observe higher level of hTERT expression in neighboring “normal tissue”. The correlation between expression levels of these three forms varied on different stages of the disease (three stages on intraepithelial neoplasias and carcinomas). The function of these three hTERT forms is still not well understood

Ways to control asynchronous motor with phase rotor of mining machines

The article describes various methods of controlling asynchronous motors with a phase rotor. To solve the problems of controlling speeds and moments in a modern electric drive, two main methods of frequency control are used: scalar and vector. Advantages and disadvantages of scalar and vector control, voltage dependence are given

Clinical and Radiographic Features of Lymphogenous Dissemination in Pulmonary Tuberculosis

At present, the attention of many researchers is focused on the disseminated tuberculosis problem due to its relevance. In some regions of Russia, disseminated tuberculosis is fairly common form of pulmonary tuberculosis. Pulmonary tuberculosis combines processes of different origins, which result from the hematogenous, bronchogenic, and lymphogenous spread of Mycobacterium tuberculosis, which is the reason for a variety of clinical and radiographic manifestations. In particular, the atypical localization of foci in the lower and middle lung segments and the atypical distribution of pulmonary lobular foci frequently lead to diagnostic errors and present problems in their interpretation. This investigation is devoted to the different variants of lymphogenous dissemination of tuberculosis with an emphasis on modern radiodiagnosis