PHYTOCHEMIMCAL ANALYSIS OF WRIGHTIA TINCTORIA BARK EXTRACT IN WATER USING GC-MS

Objective: In the present study, phytochemical constituents of crude water extract of Wrightia tinctoria (WT) bark is done using GC-MS technique. Wrightia tinctoria is an important medicinal herb being used in tribal areas of Chhattisgarh since long but chemical constituents of its bark responsible for the activities are still not studied in depth.Methods: Dried bark powder was successively extracted with petroleum ether, ethyl acetate and methanol using soxhlet apparatus and lastly material was dissolved in distilled water for 10 hrs for extraction. Water extract was selected for the further analysis using Agilent 7890A GC with 5975MS.Results: As per the GC-MS analysis, twelve different compounds namely benzene 1, 2, 4, 5-tetramethyl (2.85%), benzene 1, 2, 3, 5-tetramethyl (1.16%), 1-decanol, 2, 2-dimethyl (4.38%), phenol 2, 4-bis (1, 1-dimethyl ethyl) (7.78%), heptadecane (3.60%), 3-hexadecanol (3.30%), i-propyl tetradecanol (3.64%), benzo (h) quinoline (3.66%), n-hexadecanoic acid (6.54%), octadecanoic acid methyl ester (0.81%), phytane (1.95%) and pentadecane (2.25%) were characterized. Analysis and identification of presence of the compound in these extracts were done using the database of NIST library.Conclusion: Study confirms the presence of biologically active phyto-constituent in water extract of Wrightia tinctoria bark those may be the key chemical of natural origin in new drugs designing against major disease those are being treated in tribal areas using this plant bark. Further confirmation of in vitro bioactivity using cell line culture is required which is planned as the future prospect of current study.Â

Steam Turbine Design, Operation, and Maintenance

Discussion GroupOverhaul intervals Maintenance practices Solid particle erosion Contract versus in-house maintenance Mechanical driver turbine issues - design et al Steam path repairs Turbine casing and alignment issues Steam turbine performance, degradation, etc. Reliability/availabilit

Study of prescribing pattern of antimicrobial agents in indoor patients of a tertiary care hospital

Background: To evaluate prescribing pattern of antimicrobial agents in indoor patients of medicine and surgery department of SBH Government Medical College, Dhule.Methods: This was a retrospective cross sectional study carried over a period of 3 months. The patients who were admitted and received antimicrobial therapy in department of Medicine and Surgery were randomly selected and included in the study. The case record sheet and drug chart were obtained from Medical Record Section of the Hospital. The data was collected using case record form specially prepared for the study. The cases were categorised according to slightly Modified Kunin’s Criteria. Results: Total numbers of patients receiving antimicrobial therapy were 130 in medicine department and 93 in surgery department. Most commonly prescribed antimicrobial agent was cefotaxime (21.7%) in medicine and metronidazole in surgery (30.6%) department. The average number of antimicrobials per patient was found to be 1.7 and 3.02 in medicine and surgery department respectively. The switch on therapy from parenteral to oral route was employed in 16.15% patients in medicine department and 11.82% patients in surgery department.  As per Kunin’s modified criteria, 66.2% and 58.06% patients received antimicrobial therapy appropriately in Medicine and surgery department respectively.Conclusion: This study highlights the problem of over-prescription of antibiotics and a trend towards polypharmacy. The interventions to rectify the problem of inappropriate use of antimicrobial agents are needed to make therapy more rational and cost effective.

Steam Turbine Design, Operation, and Maintenance

Discussion Grou

Extrafollicular adenomatoid odontogenic tumor: a case report

Adenomatoid odontogenic tumor (AOT), a benign epithelial odontogenic tumor, constitutes around 2-7% of all odontogenic tumors that are biopsied. This lesion is unique with regard to its clinical, radiographic, and histopathological features making its diagnosis more predictable. This article emphasizes an extrafollicular variant of AOT leading to maxillary anterior jaw swelling along with cortical plate expansion, perforation, and root resorption within a short duration of time pointing towards its aggressive nature

Numbness and bleeding from the ear following inferior alveolar nerve block: report of a case

The inferior alveolar nerve block is a Mandibular nerve block given to anesthetize the mandibular teeth. Due to its proximity to other nerves and muscles and salivary glands it has many complications if the technique in which it is given is wrong. IANB usually presents with mild or minimal complications following it’s administration. The complications that arise are usually reversible when the action of the local anaesthetic wears off. These complications are usually associated with improper technique and anatomical variations, which can be rectified there itself with slight modifications. This is a very rare complication which has been reported where the patient has experienced numbness of the auricle on the side of inferior alveolar injection which lasted for an hour. This is seen due to the accidental anesthetic injection to the auriculotemporal nerve resulting in numbness. To perform successful inferior alveolar nerve blocks it is mandatory to be familiar with anatomical landmarks. Proper technique can reduce the complications

A Compact Dual Band E-Shape Microstrip Antenna For Wireless Application

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