Explaining immigrant citizenship status. First and second generation immigrants in fifteen European states

Citizenship acquisition is often seen as a crucial step in the process of integrating immigrants in host societies. This paper analyzes the question why some immigrants are more likely to have acquired destination country citizenship across European states than others and tests legal-formal, socioeconomic, cultural and micro-level explanations. We use a pooled dataset of first and second generation immigrants resident in 15 European states and apply a logistic multilevel analysis to measure country of origin effects, destination country effects, as well as the effects of individual level characteristics. Our analysis shows that second generation and first generation immigrants who arrived more than 20 years ago, immigrants with one parent born in the destination country, retired workers and persons speaking the host country language at home, are more likely to become a citizen of their country of residence. Second generation Muslim immigrants are less likely to have host country citizenship than comparable non-Muslim immigrants of the second generation. Immigrants from former colonies or from poor or political instable countries are more likely to become a citizen of their country of residence. Immigrants are also more likely to have acquired citizenship in destination countries with a low net migration rate and with citizenship laws that make citizenship accessible in comparative perspective.immigration; citizenship; european union; destination; origin

Explaining immigrant citizenship status. First and second generation immigrants in fifteen European states

Citizenship acquisition is often seen as a crucial step in the process of integrating immigrants in host societies. This paper analyzes the question why some immigrants are more likely to have acquired destination country citizenship across European states than others and tests legal-formal, socioeconomic, cultural and micro-level explanations. We use a pooled dataset of first and second generation immigrants resident in 15 European states and apply a logistic multilevel analysis to measure country of origin effects, destination country effects, as well as the effects of individual level characteristics. Our analysis shows that second generation and first generation immigrants who arrived more than 20 years ago, immigrants with one parent born in the destination country, retired workers and persons speaking the host country language at home, are more likely to become a citizen of their country of residence. Second generation Muslim immigrants are less likely to have host country citizenship than comparable non-Muslim immigrants of the second generation. Immigrants from former colonies or from poor or political instable countries are more likely to become a citizen of their country of residence. Immigrants are also more likely to have acquired citizenship in destination countries with a low net migration rate and with citizenship laws that make citizenship accessible in comparative perspective

Impaired barrier function by dietary fructo-oligosaccharides (FOS) in rats is accompanied by increased colonic mitochondrial gene expression

<p>Abstract</p> <p>Background</p> <p>Dietary non-digestible carbohydrates stimulate the gut microflora and are therefore presumed to improve host resistance to intestinal infections. However, several strictly controlled rat infection studies showed that non-digestible fructo-oligosaccharides (FOS) increase, rather than decrease, translocation of <it>Salmonella </it>towards extra-intestinal sites. In addition, it was shown that FOS increases intestinal permeability already before infection. The mechanism responsible for this adverse effect of FOS is unclear. Possible explanations are altered mucosal integrity due to changes in tight junctions or changes in expression of defense molecules such as antimicrobials and mucins. To examine the mechanisms underlying weakening of the intestinal barrier by FOS, a controlled dietary intervention study was performed. Two groups of 12 rats were adapted to a diet with or without FOS. mRNA was collected from colonic mucosa and changes in gene expression were assessed for each individual rat using Agilent rat whole genome microarrays.</p> <p>Results</p> <p>Among the 997 FOS induced genes we observed less mucosal integrity related genes than expected with the clear permeability changes. FOS did not induce changes in tight junction genes and only 8 genes related to mucosal defense were induced by FOS. These small effects are unlikely the cause for the clear increase in intestinal permeability that is observed. FOS significantly increased expression of 177 mitochondria-related genes. More specifically, induced expression of genes involved in all five OXPHOS complexes and the TCA cycle was observed. These results indicate that dietary FOS influences intestinal mucosal energy metabolism. Furthermore, increased expression of 113 genes related to protein turnover, including proteasome genes, ribosomal genes and protein maturation related genes, was seen. FOS upregulated expression of the peptide hormone proglucagon gene, in agreement with previous studies, as well as three other peptide hormone genes; peptide YY, pancreatic polypeptide and cholecystokinin.</p> <p>Conclusion</p> <p>We conclude that altered energy metabolism may underly colonic barrier function disruption due to FOS feeding in rats.</p

Induction of lipid oxidation by polyunsaturated fatty acids of marine origin in small intestine of mice fed a high-fat diet

Background. Dietary polyunsaturated fatty acids (PUFA), in particular the long chain marine fatty acids docosahexaenoic (DHA) and eicosapentaenoic (EPA), are linked to many health benefits in humans and in animal models. Little is known of the molecular response to DHA and EPA of the small intestine, and the potential contribution of this organ to the beneficial effects of these fatty acids. Here, we assessed gene expression changes induced by DHA and EPA in the wildtype C57BL/6J murine small intestine using whole genome microarrays and functionally characterized the most prominent biological process. Results. The main biological process affected based on gene expression analysis was lipid metabolism. Fatty acid uptake, peroxisomal and mitochondrial beta-oxidation, and omega-oxidation of fatty acids were all increased. Quantitative real time PCR, and -in a second animal experiment- intestinal fatty acid oxidation measurements confirmed significant gene expression differences and showed in a dose-dependent manner significant changes at biological functional level. Furthermore, no major changes in the expression of lipid metabolism genes were observed in the colon. Conclusion. We show that marine n-3 fatty acids regulate small intestinal gene expression and increase fatty acid oxidation. Since this organ contributes significantly to whole organism energy use, this effect on the small intestine may well contribute to the beneficial physiological effects of marine PUFAs under conditions that will normally lead to development of obesity, insulin resistance and diabete

Resectability and Ablatability Criteria for the Treatment of Liver Only Colorectal Metastases:Multidisciplinary Consensus Document from the COLLISION Trial Group

The guidelines for metastatic colorectal cancer crudely state that the best local treatment should be selected from a 'toolbox' of techniques according to patient- and treatment-related factors. We created an interdisciplinary, consensus-based algorithm with specific resectability and ablatability criteria for the treatment of colorectal liver metastases (CRLM). To pursue consensus, members of the multidisciplinary COLLISION and COLDFIRE trial expert panel employed the RAND appropriateness method (RAM). Statements regarding patient, disease, tumor and treatment characteristics were categorized as appropriate, equipoise or inappropriate. Patients with ECOG≤2, ASA≤3 and Charlson comorbidity index ≤8 should be considered fit for curative-intent local therapy. When easily resectable and/or ablatable (stage IVa), (neo)adjuvant systemic therapy is not indicated. When requiring major hepatectomy (stage IVb), neo-adjuvant systemic therapy is appropriate for early metachronous disease and to reduce procedural risk. To downstage patients (stage IVc), downsizing induction systemic therapy and/or future remnant augmentation is advised. Disease can only be deemed permanently unsuitable for local therapy if downstaging failed (stage IVd). Liver resection remains the gold standard. Thermal ablation is reserved for unresectable CRLM, deep-seated resectable CRLM and can be considered when patients are in poor health. Irreversible electroporation and stereotactic body radiotherapy can be considered for unresectable perihilar and perivascular CRLM 0-5cm. This consensus document provides per-patient and per-tumor resectability and ablatability criteria for the treatment of CRLM. These criteria are intended to aid tumor board discussions, improve consistency when designing prospective trials and advance intersociety communications. Areas where consensus is lacking warrant future comparative studies.</p

Trends and Fluctuations in Bird Populations on the Tundra at Cambridge Bay, Nunavut

Bird observations from the Cambridge Bay area on Victoria Island, Nunavut, in the summer of 2011 are presented and compared with those from the 1960s and 1980s. A total of 38 species was observed, compared with 42 in 1983 and 47 in 1986. Abundance of species of the High Arctic, such as Black Brant, Branta bernicla nigricans, Black-bellied Plover, Pluvialis squatarola, and Baird’s Sandpiper, Calidris bairdii, decreased, whereas numbers of the Red-necked Phalarope, Phalaropus lobatus, usually associated with the Low Arctic, increased markedly. Overall, the number of each species observed is rather stable and, for several species, the relative abundance does not seem to have changed significantly

MISAME

Recording of Jaap Vink's Neap Tide. Neap Tide is the last part of the bigger work "Tide" and can be considered an independent composition. Tide is based on Vink's preference for recursive processes, which stemmed from the fact that the material is directly accessible to the composer who can therefore stimulate the expressivity of the sound. While sounding complex, recursive sound means sound and its derivative can be, if desired, recorded on top of each other in one action so that the sound structure becomes more or less closed. This depends on the external intervention of the composer. The derived sounds provide the coloring. This coloration can happen quickly or slowly. For "Tide," Vink chose the latter because the tide is also a relatively slow process which requires about 6.5 hours for completion. In order not to try the listener's patience too much, "Tide" is about 45 minutes long, "Neap Tide" being the 20 minute ending section of the work

MISAME

Recording of Jaap Vink's Résidicals I

Adaptive Selling and Organizational Characteristics: Suggestions For Future Research

In this paper the relationship between adaptive selling and organizational behavior is analysed. Specifically, it is discovered that adaptive behavior is a multifaceted concept which is not linearly related to the organizational characteristics in the way it was operationalized in a former study by Sujan and Weitz. In order to gain a better insight into the functioning of adaptive selling within organizations, a different methodology is suggested. By means of more inductive research more detailed models should be generated, which then can be tested for robustness with a more deductive approach. Concept creation should have a more empirical foundation before concepts are entered into a theoretical network