4 research outputs found
Pallium Canada's curriculum development model: A framework to support large-scale courseware development and deployment
The need to improve access to palliative care across multiple settings and disease groups has been identified. This
requires equipping health care professionals from many different professions, including physicians and nurses,
among others, with basic palliative care competencies to provide a palliative care approach. Pallium Canadaâs
Curriculum Development Framework supports the development, deployment, and dissemination, on a large scale,
of multiple courses targeting health care professionals across multiple settings of care and disease groups. The
Framework is made up of eight phases: (1) Concept, (2) Decision, (3) Curriculum Planning, (4) Prototype Development, (5) Piloting, (6) Dissemination, (7) Language and Cultural Adaptation, and (8) Ongoing Maintenance
and Updates. Several of these phases include iterative cyclical activities. The framework allows multiple courses to
be developed simultaneously, staggered in a production line with each phase and their corresponding activities
requiring different levels of resources and stakeholder engagement. The framework has allowed Pallium Canada to
develop, launch, and maintain numerous versions of its Learning Essential Approaches to Palliative Care (LEAP)
courses concurrently. It leverages existing LEAP courses and curriculum materials to produce new LEAP courses,
allowing significant efficiencies and maximizing output. This article describes the framework and its various
activities, which we believe could be very useful for other jurisdictions undertaking the work of developing
education programs to spread the palliative care approach across multiple settings, specialties, and disease groups
The Helicobacter pylori Genome Project : insights into H. pylori population structure from analysis of a worldwide collection of complete genomes
Helicobacter pylori, a dominant member of the gastric microbiota, shares co-evolutionary history with humans. This has led to the development of genetically distinct H. pylori subpopulations associated with the geographic origin of the host and with differential gastric disease risk. Here, we provide insights into H. pylori population structure as a part of the Helicobacter pylori Genome Project (HpGP), a multi-disciplinary initiative aimed at elucidating H. pylori pathogenesis and identifying new therapeutic targets. We collected 1011 well-characterized clinical strains from 50 countries and generated high-quality genome sequences. We analysed core genome diversity and population structure of the HpGP dataset and 255 worldwide reference genomes to outline the ancestral contribution to Eurasian, African, and American populations. We found evidence of substantial contribution of population hpNorthAsia and subpopulation hspUral in Northern European H. pylori. The genomes of H. pylori isolated from northern and southern Indigenous Americans differed in that bacteria isolated in northern Indigenous communities were more similar to North Asian H. pylori while the southern had higher relatedness to hpEastAsia. Notably, we also found a highly clonal yet geographically dispersed North American subpopulation, which is negative for the cag pathogenicity island, and present in 7% of sequenced US genomes. We expect the HpGP dataset and the corresponding strains to become a major asset for H. pylori genomics
Pallium Canada's curriculum development model: A framework to support large-scale courseware development and deployment
The need to improve access to palliative care across multiple settings and disease groups has been identified. This
requires equipping health care professionals from many different professions, including physicians and nurses,
among others, with basic palliative care competencies to provide a palliative care approach. Pallium Canadaâs
Curriculum Development Framework supports the development, deployment, and dissemination, on a large scale,
of multiple courses targeting health care professionals across multiple settings of care and disease groups. The
Framework is made up of eight phases: (1) Concept, (2) Decision, (3) Curriculum Planning, (4) Prototype Development, (5) Piloting, (6) Dissemination, (7) Language and Cultural Adaptation, and (8) Ongoing Maintenance
and Updates. Several of these phases include iterative cyclical activities. The framework allows multiple courses to
be developed simultaneously, staggered in a production line with each phase and their corresponding activities
requiring different levels of resources and stakeholder engagement. The framework has allowed Pallium Canada to
develop, launch, and maintain numerous versions of its Learning Essential Approaches to Palliative Care (LEAP)
courses concurrently. It leverages existing LEAP courses and curriculum materials to produce new LEAP courses,
allowing significant efficiencies and maximizing output. This article describes the framework and its various
activities, which we believe could be very useful for other jurisdictions undertaking the work of developing
education programs to spread the palliative care approach across multiple settings, specialties, and disease groups