Cellulites périnéales (essai de classification anatomique pronostique à partir d'une étude rétrospective de 57 cas)

ANGERS-BU Médecine-Pharmacie (490072105) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

Comment les patients insuffisants respiratoires chroniques trachéotomisés évaluent-ils leur qualité de vie et leur prise en charge au CHU d Angers ?

ANGERS-BU Médecine-Pharmacie (490072105) / SudocSudocFranceF

LES METASTASES CEREBRALES INAUGURALES DES CANCERS BRONCHO-PULMONAIRES PRIMITIFS (ETUDE RETROSPECTIVE DE 63 CAS (DES PNEUMOLOGIE))

ANGERS-BU Médecine-Pharmacie (490072105) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

Les effets indésirables neurologiques et oculaires de l'oxygénothérapie hyperbare

TOURS-BU Sciences Pharmacie (372612104) / SudocSudocFranceF

Clinical consequences related to a defective elimination of clobazam caused by homozygous mutated CYP2C19 allele

International audienc

Enriched Air Nitrox Breathing Reduces Venous Gas Bubbles after Simulated SCUBA Diving: A Double-Blind Cross-Over Randomized Trial

<div><p>Objective</p><p>To test the hypothesis whether enriched air nitrox (EAN) breathing during simulated diving reduces decompression stress when compared to compressed air breathing as assessed by intravascular bubble formation after decompression.</p><p>Methods</p><p>Human volunteers underwent a first simulated dive breathing compressed air to include subjects prone to post-decompression venous gas bubbling. Twelve subjects prone to bubbling underwent a double-blind, randomized, cross-over trial including one simulated dive breathing compressed air, and one dive breathing EAN (36% O₂) in a hyperbaric chamber, with identical diving profiles (28 msw for 55 minutes). Intravascular bubble formation was assessed after decompression using pulmonary artery pulsed Doppler.</p><p>Results</p><p>Twelve subjects showing high bubble production were included for the cross-over trial, and all completed the experimental protocol. In the randomized protocol, EAN significantly reduced the bubble score at all time points (cumulative bubble scores: 1 [0–3.5] vs. 8 [4.5–10]; P < 0.001). Three decompression incidents, all presenting as cutaneous itching, occurred in the air versus zero in the EAN group (P = 0.217). Weak correlations were observed between bubble scores and age or body mass index, respectively.</p><p>Conclusion</p><p>EAN breathing markedly reduces venous gas bubble emboli after decompression in volunteers selected for susceptibility for intravascular bubble formation. When using similar diving profiles and avoiding oxygen toxicity limits, EAN increases safety of diving as compared to compressed air breathing.</p><p>Trial Registration</p><p><a href="http://www.isrctn.com/ISRCTN31681480" target="_blank">ISRCTN 31681480</a></p></div

Simulated diving profile.

<p>Study compression profile as used for all simulated dives to a maximum depth of 28 msw, followed by two decompression steps at 6 msw and 3 msw. For further details see text.</p