Investigation of Electromagnetic Radiation Emission during Sheet Metal Incremental Micro Forming

<div><p>Edge dislocations within the plastic zone ahead of a crack tip form accelerated electric line dipoles which give rise to the electromagnetic radiation (EMR) emissions in metal and alloys. This paper reports an experimental investigation to determine EMR radiation during incremental microforming of a thin aluminum sheet. The EMR signals emit from aluminum grade Al3003 during deformation under unrestricted quasi-static micro-deformation is reported. The EMR emission characteristics are influenced by the microstructural changes rather than forming parametric conditions. The EMR emissions are followed by micro-deformation locally in predetermined loci in continuous deformation pattern through a rotating tool with two different depths. The nature, amplitude and frequency of the observed EMR emissions are in conformity with the predictions of the theoretical model developed by the Misra and co-authors.24-29</p></div

MOESM1 of Antiproliferative and apoptotic effects of black turtle bean extracts on human breast cancer cell line through extrinsic and intrinsic pathway

Additional file 1: Figure S1. PI staining assay showing the dead cells when treated with BTB extract (50 and 100 ¾g/ml) in MCF-7 and MDA-MB231 cells, respectively

Anticancer Activity of Iridium(III) Complexes Based on a Pyrazole-Appended Quinoline-Based BODIPY

A pyrazole-appended quinoline-based 4,4-difluoro-4-bora-3a,4a-diaza-<i>s</i>-indacene (<b>L1</b>, BODIPY) has been synthesized and used as a ligand for the preparation of iridium­(III) complexes [Ir­(phpy)₂(<b>L1</b>)]­PF₆ (<b>1</b>; phpy = 2-phenylpyridine) and [(η⁵-C₅Me₅)­Ir­(<b>L1</b>)­Cl]­PF₆ (<b>2</b>). The ligand <b>L1</b> and complexes <b>1</b> and <b>2</b> have been meticulously characterized by elemental analyses and spectral studies (IR, electrospray ionization mass spectrometry, ¹H and ¹³C NMR, UV/vis, fluorescence) and their structures explicitly authenticated by single-crystal X-ray analyses. UV/vis, fluorescence, and circular dichroism studies showed that complexes strongly bind with calf-thymus DNA and bovine serum albumin. Molecular docking studies clearly illustrated binding through DNA minor grooves via van der Waals forces and their electrostatic interaction and occurrence in the hydrophobic cavity of protein (subdomain IIA). Cytotoxicity, morphological changes, and apoptosis have been explored by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay and Hoechst 33342 staining. IC₅₀ values for complexes (<b>1</b>, 30 μM; <b>2</b>, 50 μM) at 24 h toward the human cervical cancer cell line (HeLa) are as good as that of cisplatin (21.6 μM) under analogous conditions, and their ability to kill cancer cells lies in the order <b>1</b> > <b>2</b>. Because of the inherent emissive nature of the BODIPY moiety, these are apt for intracellular visualization at low concentration and may find potential applications in cellular imaging and behave as a theranostic agent

List of the 73 EST and genomic SSRs primers used in present study.

<p>List of the 73 EST and genomic SSRs primers used in present study.</p

Neighbour joining dendrogram of 96 genotype of lentil with 73 SSRs (Serial number of genotype in the figure corresponds with serial number and genotype in Table 1).

<p>Neighbour joining dendrogram of 96 genotype of lentil with 73 SSRs (Serial number of genotype in the figure corresponds with serial number and genotype in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0188296#pone.0188296.t001" target="_blank">Table 1</a>).</p

Linkage disequilibrium patterns among 96 genotypes genotyped with 73 SSRs.

<p>The squared correlation coefficients (r²) for each pair of markers are presented in the upper triangle and their corresponding p values in the lower triangle.</p

Source / Origin of 96 genotypes of lentil used in the study.

<p>Source / Origin of 96 genotypes of lentil used in the study.</p

Favorable alleles for grain Fe and Zn concentration.

<p>Favorable alleles for grain Fe and Zn concentration.</p

Manhattan plot depicting association of 73 SSRs markers with grain iron concentration for (A) Delhi (2013–14) (B) Dharwad (2013–14) (C) Indore (2013–14) (D) Delhi (2014–15) (E) Combined all location year.

<p>Manhattan plot depicting association of 73 SSRs markers with grain iron concentration for (A) Delhi (2013–14) (B) Dharwad (2013–14) (C) Indore (2013–14) (D) Delhi (2014–15) (E) Combined all location year.</p