9 research outputs found
INOR 197-Polymetallic lanthanide complexes of multiple azamacrocyclic binding sites incorporating different chromophores
INOR 962-Polyheterometallic lanthanide complexes exhibiting multiple spectroscopic signatures
Synthesis and bioactivity of nobilamide B
An alternative and facile solution/solid-phase approach is reported for the total synthesis of neuroactive peptide, nobilamide B. Z-Dhb was formed in solution via EDC/CuCl induced elimination. The solid-phase synthesis employed HBTU/Oxyma Pure™ coupling using Barlos resin. Synthetic nobilamide B was also found to be neuroactive in primary cultures of dorsal root ganglion (DRG) neurons. © the Partner Organisations 2014
Synthesis and bioactivity of nobilamide B
An alternative and facile solution/solid-phase approach is reported for the total synthesis of neuroactive peptide, nobilamide B. Z-Dhb was formed in solution via EDC/CuCl induced elimination. The solid-phase synthesis employed HBTU/Oxyma Pure™ coupling using Barlos resin. Synthetic nobilamide B was also found to be neuroactive in primary cultures of dorsal root ganglion (DRG) neurons. © the Partner Organisations 2014
In situ targeted MRI detection of Helicobacter pylori with stable magnetic graphitic nanocapsules
Emerging Opportunities in the Biomedical Applications of Dendrimers
The medical field remains challenged with many unmet needs, prompting rigorous research for solutions. Dendrimers are emerging as innovative solutions to many unmet clinical needs. Indeed, commercial dendrimer-enabled gene transfection technologies exist and work is ongoing to translate many other dendrimer products into the market to assist patients. Here, we review the ongoing work on dendrimer-enabled drug delivery technologies, diagnostic platforms, and antimicrobial agents. Our goal is to inspire the continuous exploration of the dendritic scaffold to address many issues in the biomedical landscape