17,062 research outputs found
Robustness of the O() universality class
We calculate the critical exponents for Lorentz-violating O()
scalar field theories by using two independent methods. In
the first situation we renormalize a massless theory by utilizing normalization
conditions. An identical task is fulfilled in the second case in a massive
version of the same theory, previously renormalized in the BPHZ method in four
dimensions. We show that although the renormalization constants, the
and anomalous dimensions acquire Lorentz-violating quantum corrections, the
outcome for the critical exponents in both methods are identical and
furthermore they are equal to their Lorentz-invariant counterparts. Finally we
generalize the last two results for all loop levels and we provide symmetry
arguments for justifying the latter
One-loop conformal anomaly in an implicit momentum space regularization framework
In this paper we consider matter fields in a gravitational background in
order to compute the breaking of the conformal current at one-loop order.
Standard perturbative calculations of conformal symmetry breaking expressed by
the non-zero trace of the energy-momentum tensor have shown that some violating
terms are regularization dependent, which may suggest the existence of spurious
breaking terms in the anomaly. Therefore, we perform the calculation in a
momentum space regularization framework in which regularization dependent terms
are judiciously parametrized. We compare our results with those obtained in the
literature and conclude that there is an unavoidable arbitrariness in the
anomalous term .Comment: in European Physical Journal C, 201
BP Reduction, Kidney Function Decline, and Cardiovascular Events in Patients without CKD.
BACKGROUND AND OBJECTIVES:
In the Systolic Blood Pressure Intervention Trial (SPRINT), intensive systolic BP treatment (target <120 mm Hg) was associated with fewer cardiovascular events and higher incidence of kidney function decline compared with standard treatment (target <140 mm Hg). We evaluated the association between mean arterial pressure reduction, kidney function decline, and cardiovascular events in patients without CKD.
DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS:
We categorized patients in the intensive treatment group of the SPRINT according to mean arterial pressure reduction throughout follow-up: <20, 20 to <40, and ≥40 mm Hg. We defined the primary outcome as kidney function decline (≥30% reduction in eGFR to <60 ml/min per 1.73 m2 on two consecutive determinations at 3-month intervals), and we defined the secondary outcome as cardiovascular events. In a propensity score analysis, patients in each mean arterial pressure reduction category from the intensive treatment group were matched with patients from the standard treatment group to calculate the number needed to treat regarding cardiovascular events and the number needed to harm regarding kidney function decline.
RESULTS:
In the intensive treatment group, 1138 (34%) patients attained mean arterial pressure reduction <20 mm Hg, 1857 (56%) attained 20 to <40 mm Hg, and 309 (9%) attained ≥40 mm Hg. Adjusted hazard ratios for kidney function decline were 2.10 (95% confidence interval, 1.22 to 3.59) for mean arterial pressure reduction between 20 and 40 mm Hg and 6.22 (95% confidence interval, 2.75 to 14.08) for mean arterial pressure reduction ≥40 mm Hg. In propensity score analysis, mean arterial pressure reduction <20 mm Hg presented a number needed to treat of 44 and a number needed to harm of 65, reduction between 20 and <40 mm Hg presented a number needed to treat of 42 and a number needed to harm of 35, and reduction ≥40 mm Hg presented a number needed to treat of 95 and a number needed to harm of 16.
CONCLUSIONS:
In the intensive treatment group of SPRINT, larger declines in mean arterial pressure were associated with higher incidence of kidney function decline. Intensive treatment seemed to be less favorable when a larger reduction in mean arterial pressure was needed to attain the BP target.info:eu-repo/semantics/publishedVersio
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