A comment on 'Operationalizing Max Weber's probability concept of class situation: the concept of social class' by Ken Smith

Schematic representation of APC activation in wt and myeloid pten -/- animals. In wt, APCs are activated and initiate autoimmunity by activating and polarizing T cells toward the Th17 lineage. PTEN-deficient APCs fail to induce autoimmunity due to sustained PI3K signaling, leading to altered signaling and reduced polarizing cytokine expression. (JPEG 294 kb