Trends in Microextraction Techniques for Sample Preparation

Micro-extraction techniques in sample preparation are gaining interest among analytical chemists as they comply with green analytical chemistry demands and ensure environmental protection and public safety. Savings in cost and time are considered as valuable benefits by using novel micro-extraction approaches in sample handling. Selectivity, sensitivity and lower detection limits are also included among the performance characteristics required to meet the legislation criteria. The target of this special issue is to present the state of art in microextraction sample preparation techniques. Modern, simple and efficient methods for preconcentration and separation are described for different analytes isolated from various matrices

Applications of Gas Chromatography for the Analysis of Tricyclic Antidepressants in Biological Matrices

Tricyclic antidepressant drugs (TCAs) are a main category of antidepressants, which are until today widely used for the treatment of psychological disorders due to their low cost and their high efficiency. Therefore, there is a great demand for method development for the determination of TCAs in biofluids, especially for therapeutic drug monitoring. Gas chromatography (GC) was the first chromatographic technique implemented for this purpose. With the recent development in the field of sample preparation, many novel GC applications have been developed. Herein, we aim to report the recent application of GC for the determination of tricyclic antidepressants in biofluids. Emphasis is given to novel extraction techniques and novel materials used for sample preparation

Metal Organic Frameworks: Synthesis and Application

The concept of metal–organic frameworks (MOFs) was first introduced in 1990; nowadays they are among the most promising novel materials [...