Flow diagram for study selection.

<p>Flow diagram for study selection.</p

Evaluation of feasibility of all methods according to ASSURED criteria.

<p>1† = specificity of these techniques is assumed to be 100%.</p

Summary of published sensitivity and specificity estimates of several molecular methods techniques for HAT.

<p>Summary of published sensitivity and specificity estimates of several molecular methods techniques for HAT.</p

Annual case notification of HAT in DRC, 1926–2011.

<p>Source: PNLTHA.</p

Geographic locations of the health zones included in the study.

<p>Geographic locations of the health zones included in the study.</p

Citations illustrating the prohibitions linked to the resting period after treatment.

<p>Citations illustrating the prohibitions linked to the resting period after treatment.</p

Prevalence data for the health zones included in the study.

<p>Source: 2005 and 2007 annual reports of the national control programme division of Kasai-Oriental.</p

Sensitivity of CATT and prototype SD BIOLINE HAT RDT on fresh blood by stage of disease.

<p>Sensitivity of CATT and prototype SD BIOLINE HAT RDT on fresh blood by stage of disease.</p

Sites in Angola, CAR and the DRC where participants were enrolled by both passive and active screening.

<p>Prevalence was calculated on the basis of combined active and passive screening results from this study.</p

Overview of the results of the CATT and RDT tests in Angola, CAR and the DRC.

<p>RDT: SD BIOLINE HAT rapid diagnostic test. CATT: card agglutination test for trypanosomiasis. * 1 case that was negative on CATT whole blood and the RDT was detected by CATT 1/8 dilution. ** a = Angola; b = Central African Republic; c = Democratic Republic of the Congo. / = and/or</p