Univariate analysis of the biologic factors predictive of survival in DLBCL.

<p>Univariate analysis of the biologic factors predictive of survival in DLBCL.</p

Correlation between MYC immunohistochemistry and <i>MYC</i> rearrangement.

<p><i>p</i>-value <0.00010.</p

Overall survival of patients with DLBCL based on alterations in MYC, BCL2 and FOXP1.

<p>Kaplan Meier curves represents OS according to A) MYC protein expression, B) FOXP1 protein expression, C) presence of MYC and BCL2 expression, D) <i>MYC</i> translocation, E) <i>BCL2</i> translocation, F) BCL2 protein expression.</p

Correlation between FISH status and MYC immunohistochemistry results.

<p>Correlation between FISH status and MYC immunohistochemistry results.</p

Recurrence-free survival curves and CD133- positivity expression.

<p>Recurrence-free survival curves and CD133- positivity expression.</p

Group of neoplastic cells showing CD 133 positive cytoplasmic expression.

<p>Group of neoplastic cells showing CD 133 positive cytoplasmic expression.</p

Kaplan-Meier curve for recurrence and survival.

<p>Kaplan-Meier curve for recurrence and survival.</p

Most neoplastic cells express null or weak CK20. However, there are groups of cells expressing simultaneously CD 133 and CK 20 (encircled areas).

<p>Most neoplastic cells express null or weak CK20. However, there are groups of cells expressing simultaneously CD 133 and CK 20 (encircled areas).</p

Most neoplastic cells express CD133.

<p>Most neoplastic cells express CD133.</p

CD 133 protein expression in the apical border of cancer cells, shedding CD 133 positive debris into the luminal glands.

<p>CD 133 protein expression in the apical border of cancer cells, shedding CD 133 positive debris into the luminal glands.</p