Flow over weirs with thin edges and full contractions

Thesis (Civil Engineering)--University of Kansas, Civil Engineering, 1915. ; Includes bibliographical references

Black Holes in the Gauge Theoretic Formulation of Dilatonic Gravity

We show that two-dimensional topological BF theories coupled to particles carrying non-Abelian charge admit a new coupling involving the Lagrange multiplier field. When applied to the gauge theoretic formulation of dilatonic gravity it gives rise to a source term for the gravitational field. We show that the system admits black hole solutions.Comment: Action is improved to be reparametrization invariant. Misprintings corrected. 10 pages, Late

The peculiarities of working capital management at agroindustrial enterprises of Ukraine

Achieving the balance in the formation of working capital is a prerequisite for stable development of enterprises and improvement of the economic situation in Ukraine as a whole that is especially relevant during the period of socio-economic crisis. The study of working capital management peculiarities of agricultural enterprises deserves special attention, since their contribution to the national economy is significant.The purpose of the article is to investigate methods of assessing the efficiency of formation of enterprises working capital and prospects for its application to characterize the current state of domestic agricultural enterprises activity. The object of the research is determining the actual model of working capital financing at Ukrainian agricultural enterprises.In the article, the efficiency of formation and use of working capital in Ukrainian agricultural sector is analyzed. The actual model of working capital financing of enterprises in this sector is determined. It is typical for this sphere to adhere the aggressive policy of current assets formation, which increases the risk of loss of the solvency and financial stability. Optimization of sources of working capital financing at domestic agricultural enterprises will increase the volume of economic activity financing and improve the enterprises liquidity

901-90 In Vivo Genetic Engineering of Cardiac Cells: Intracoronary Administration of Antisense (AS) Oligonucleotides (ODN)

We have previously documented that transfection of antisense ODN by a highly efficient Sendai virus (HVJ)-liposome delivery system can be utilized to modify lesion formation within the peripheral vasculature in vivo. In this study, we defined the feasibility of modifying cardiac cell gene expression via a catheter-based coronary infusion of AS ODN in rabbits. The coronary artery was cannulated via an over-the-wire approach from the carotid artery. Fluorescein (F)-Iabeled ODN were utilized to evaluate the cellular distribution and kinetics of ODN uptake within the myocardium after a single intraluminal bolus of HVJ-liposomes containing ODN. Cellular uptake of F-ODN was primarily localized in the microvasculature and significant staining was also observed in conduit vessels and cardiac myocytes. Immunohistochemical analysis verified prominent localization of F-ODN within the microvascular endothelium. Expression of F-ODN was observed within 10 minutes, peaked at 1 day, and remained evident for up to one week after transfection by the HVJ-liposome method. In contrast, F-ODN infused within liposomes without the viral particle exhibited transient expression that was undetectable within 3 days. These findings indicate that a single intracoronary bolus infusion of ODN within HVJ-liposomes is a reproducible methodology for delivery of AS ODN to targeted cells within the myocardium. Future studies will characterize the feasibility of using this approach to modify cardiac structure and function via regulating myocardial cell gene expression

Apoptosis and schizophrenia: a pilot study based on dermal fibroblast cell lines

Introduction: The aim of this study was to investigate whether there is an increased susceptibility to apoptosis in cultured fibroblasts from patients with schizophrenia