Synthesis and antibacterial activity of some new schiff bases and 2-Azetidinones containing iodohyydroxy biphenyl moiety

2-Hydroxy-5-phenylbenzaldehyde on iodination yielded 2-Hydroxy-3-iodo-5-phenylbenzaldehyde. This aldehyde on facile condensation with substituted aromatic amines in presence of catalytic amount of acetic acid to afford new series of Schiff bases. Further these Schiff bases on cyclocondensation reaction with chloroacetyl chloride afforded a biologically active 2-azetidinones derivatives. The structure of newly synthesized compounds characterized on the basis of elemental analysis and spectral data. The compounds prepared were tested against Xanthomonas citri, Escherichia coli, Erwinia carotovora and Bacillus subtilis. Some of these compounds showed potential antibacterial activity

Solvent-free, Environmentally Benign Syntheses of Some Imines and Antioxidant Activity

Environmentally benign, economically feasible, and solvent-free syntheses of series of imines by the condensation of a substituted hydroxynaphthyl ketone with several substituted iodoanilines under grinding approach are described. Imines were further tested for antioxidant activity; most of them show moderate activity. DOI: http://dx.doi.org/10.17807/orbital.v7i3.60

Solvent-free, Environmentally Benign Syntheses of Some Imines and Antioxidant Activity

Environmentally benign, economically feasible, and solvent-free syntheses of series of imines by the condensation of a substituted hydroxynaphthyl ketone with several substituted iodoanilines under grinding approach are described. Imines were further tested for antioxidant activity; most of them show moderate activity. DOI: http://dx.doi.org/10.17807/orbital.v7i3.608 </p

Green approach for the synthesis of some new α, β-unsaturated ketimines under water suspension

An environmentally benign and efficient synthesis of some a,ß-unsaturated ketimines from new 2-hydroxychalcone and different aromatic amines under water suspension. The remarkable advantages offered by this method are environmentally friendly, short reaction times, non-hazardous, simple work-up procedure and good to excellent yields of products.</div

2-Methoxyethanol as an alternative reaction solvent for the synthesis of 1,5-benzodiazepines under microwave irradiation

An improved condensation reaction between substituted 2’-hydroxychalcones and o-phenylenediamine using piperidine in 2-methoxyetahnol as an efficient and alternative reaction medium. The clean reaction conditions, easy work up, time saving and higher yields are notable advantages of present method.</div