242 research outputs found
Motivation for Pursuing Further Education amongst Adult Learners
El presente artículo se basa en un estudio cuyo objeto es comprender la motivación y las experiencias de personas de la tercera edad a la hora de obtener el Diploma en Gerontología otorgado por el Centro para el Aprendizaje Permanente, del Instituto Tata de Ciencias Sociales, en Bombay (la India). La cuestión de lo que motiva a los adultos de mayor edad a participar en actividades educativas es importante, especialmente desde la perspectiva del envejecimiento activo. Se seleccionaron seis de un total de trece alumnos pertenecientes a la tercera edad, a quienes se entrevistó en profundidad. Se empleó una metodología cualitativa, que incluye el análisis de contenido, para explorar las experiencias y los antecedentes de las personas de la tercera edad y llegar a obtener un conocimiento sobre su participación en las actividades de aprendizaje mientras cursan el Diploma en Gerontología. Se analizan su motivación, sus experiencias, sus retos y sus beneficios al participar en el aprendizaje permanente. Una de las principales conclusiones del estudio es que, a pesar de que el curso se describe como riguroso y exigente en cuanto al esfuerzo que requiere, se comprueba que los alumnos han percibido un impacto positivo sobre su bienestar social, psicológico e incluso físico. Los métodos de enseñanza favoritos entre los adultos de la tercera edad son las actividades de grupo, el debate y los proyectos basados en las tareas docentes, antes que los exámenes escritos. El estudio recomienda mayor divulgación y publicidad de tales programas educativos entre la tercera edad, y conseguir que los cursos sean más adecuados para las personas mayores, de forma que puedan convertirse en un componente integral del envejecimiento activo.The present paper is based on a study aimed at understanding the motivation and experiences of senior citizen learners in pursuing Diploma in Gerontology at Centre for Lifelong Learning, Tata Institute of Social Sciences, Mumbai. The issue of what motivates older adults to participate in educational activities is important specially from the perspective of Active Ageing. Six out of the total thirteen senior citizen learners were selected and interviewed in depth. Qualitative methodology, including content analysis was used to explore older persons’ backgrounds and experiences, and to gain an understanding of their involvement in the learning activities while pursuing Diploma in Gerontology. Their motivation, experiences, challenges, and benefits of engagement in lifelong learning are discussed. One of the major findings of the study is that, despite the course being described as rigorous and demanding in terms of hard work, the learners are found to have perceived a positive impact on their social, psychological and even physical wellbeing. The most preferred teaching method among senior citizen learners are group activities, discussion and assignment-based projects over written examinations. The study recommends more awareness and publicity of such educational programmes among the elderly and courses more elder-friendly so that they may become an integral component in active ageing
Screening of pregnant women for cervical malignancies
This study was carried out on a cross-sectional prospective basis on 590 pregnant women attending ante natal OPD in government medical college and hospital over a period of 1 year during their routine ante natal check up for screening cervical malignancies. The data obtained were analysed. 99% of the cases were less than 30 years of age. No single case of cervical dysplasia or malignancy was reported. Considering that we have limited resources, screening these young patients in whom we expect low incidence of pre cancer or cancerous lesions doesn’t appear to be a very good approach.
Cryptography for Secure E-mail Communication
Users share private information on the web through a variety of applications, suchas email, instant messaging, social media, and document sharing. Unfortunately, recentrevelations have shown that not only is users' data at risk from hackers and malicious insiders,but also from government surveillance. This state of affairs motivates the need for users tobe able to encrypt their online data specifically the e-mail communication. This paper shows the use of cryptographic algorithms for secure e-mail communication
Pretty Good Privacy: An e-mail Security Protocol
Security has been an issue in mail from ancient times. Security is still important today.E-mail is as fast and casual as a voice phone call, but can be save and retrieved withinfinitely greater efficiency than paper letters or taped conversations. Security in maildeals first with reliable delivery to the addressee. Security, that is confidential, reliableand known delivery is essential to the success of e-mail. In other words people will notuse a mail system that they cannot trust to deliver their messages. This paper describes the basic approaches for e-mail security and discusses the advanced email security mechanism i.e. Pretty Good Privacy (PGP
Prevalence of computer vision syndrome and associated ocular morbidity in a tertiary care hospital
Background: This study was done to determine the prevalence of computer vision syndrome and associated ocular morbidity in a tertiary care hospital.
Methods: A cross sectional observational study was conducted on 673 patients based on the inclusion criteria. The patients were asked to fulfil the computer vision syndrome survey form 3 and OSDI questionnaire. Spontaneous eye blink rate, Schirmer’s test 1, tear break up time, refraction were performed for these patients. Data was collected and analysed by SPSS software.
Results: The prevalence of computer vision syndrome was 73% with 294 males and 206 females. The mean age of the patients was 30.29 years. Most of the participants were between 21-30 years. The screen time for most of the study participants (59.80%) came out to be >6 hours/day on average. The chief complaint of majority patients was blurred vision and asthenopia whereas the secondary complaint was watering and headache. Maximum patients (38.20%) from our study were students and competitive exam aspirants followed by teachers and software engineers. The screen modality used by 34.20 % patients was mobile phones > laptops. The mean SEBR was 13.50 minutes. The mean OSDI was 17.44. The screen time was significantly correlated to SEBR (p<0.0001). Also the screen time and OSDI correlation came out to be significant (p<0.0001).
Conclusions: The present study revealed a significantly high prevalence of CVS among our patients. The ocular symptoms are predominantly affecting the convergence power of eyes and tear film instability causing blurred vision and dryness
A Scoping review of challenges, scope and assessment approaches of teledentistry: an Indian perspective
Context: In India, COVID-19 pandemic has limited the utilization and access to dental services owing to the risk of infections transmission. In this context, tele-dentistry could be useful but there is paucity of literature which provides guidance on the scope and challenges for using tele-dentistry in India. Aims: To identify challenges, scope and assessment approaches of tele-dentistry from an Indian perspective. Settings and Design: Scoping Review. Methods and Material: Scoping review was conducted using the Arksey and O’Malley framework. Databases were searched in July from April to August 2020. Studies concerning challenges and scope of tele-dentistry in India were included. Additionally, literature about assessment approaches used for tele-dentistry programs were also reviewed Results: A total of 64 studies were reviewed, out of which 26 articles were included in the final review. Scoping review reveled that tele-dentistry can act as a seamless tool for diagnosing, training and screening. Few studies suggested the relevance of smartphone technology for specialist consultations and proper diagnosis. Majority of studies revealed shortage of basic infrastructure as a major challenge for tele-dentistry in India. Assessment studies were mainly focused on economic perspective and cost-effectiveness of the programs. Conclusions: This review provide guidance for using tele-dentistry in India. It is also reflected that there is a need for further research about the assessment of tele-dentistry in terms of safety, clinical outcomes, and patient perception
Development and Characterization of Morin Loaded Phytosomes for its Anti-Oxidant Activity
The herbal plants contain huge number of active constituents, which shows excellent biological activity in-vitro but less in-vivo because of their poor lipid solubility, improper molecules size, degradation in gastric fluid and destruction of active components in gut by bacteria. So that poor absorption and bioavailability may occur. Phytosomal technique can be applied to herbal actives for the enhancement of bioavailability of herbal extracts and phytoconstituents. Phytosomes are prepared by patented process where standardized plant extract are bound to phospholipid. The aim of the present study was to developed and characterized the phytosomes of Morin to overcome the limitation of absorption and bioavailability. Phytosomes of Morin was formulated by thin film hydration method by using in different ratio of lipid with phytoconstituents. The prepared phytosomes were characterized for their drug content, drug entrapment, particle size, in-vitro release study and evaluated its in vitro antioxidant activity. From the present study, the result showed that spherical shape phytosomes having particle size 661.2nm. The poly-dispersity index and zeta potential was found to be 0.383 and -13.76 mv respectively. Result obtained from in-vitro release studies shows a sustained release of morin from formulation over a period of 12 hrs. From the present study it was concluded that morin loaded phytosmes shows better absorption and more effective antioxidants than the parent compound.
Keyword: Phytosomes, phospholipids, Morin, in-vitro Antioxidant activit
NEK1 Phosphorylation of YAP Promotes Its Stabilization and Transcriptional Output
Most prostate cancer (PCa) deaths result from progressive failure in standard androgen deprivation therapy (ADT), leading to metastatic castration-resistant PCa (mCRPC); however, the mechanism and key players leading to this are not fully understood. While studying the role of tousled-like kinase 1 (TLK1) and never in mitosis gene A (NIMA)-related kinase 1 (NEK1) in a DNA damage response (DDR)-mediated cell cycle arrest in LNCaP cells treated with bicalutamide, we uncovered that overexpression of wt-NEK1 resulted in a rapid conversion to androgen-independent (AI) growth, analogous to what has been observed when YAP1 is overexpressed. We now report that overexpression of wt-NEK1 results in accumulation of YAP1, suggesting the existence of a TLK1\u3eNEK1\u3eYAP1 axis that leads to adaptation to AI growth. Further, YAP1 is co-immunoprecipitated with NEK1. Importantly, NEK1 was able to phosphorylate YAP1 on six residues in vitro, which we believe are important for stabilization of the protein, possibly by increasing its interaction with transcriptional partners. In fact, knockout (KO) of NEK1 in NT1 PCa cells resulted in a parallel decrease of YAP1 level and reduced expression of typical YAP-regulated target genes. In terms of cancer potential implications, the expression of NEK1 and YAP1 proteins was found to be increased and correlated in several cancers. These include PCa stages according to Gleason score, head and neck squamous cell carcinoma, and glioblastoma, suggesting that this co-regulation is imparted by increased YAP1 stability when NEK1 is overexpressed or activated by TLK1, and not through transcriptional co-expression. We propose that the TLK1\u3eNEK1\u3eYAP1 axis is a key determinant for cancer progression, particularly during the process of androgen-sensitive to -independent conversion during progression to mCRPC
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