Role of Parasites in Cancer

BACKGROUND: In areas of parasitic endemicity, the occurrence of cancer that is not frequent may be linked with parasitic infection. Epidemiological ,correlates between some parasitic infections and cancer is strong, suggesting a strong aetiological association. The common parasites associated with human cancers are schistosomiasis, malaria, liver flukes (Clonorchis ,sinenses, Opistorchis viverrini).OBJECTIVE:  To review the pathology, literature and methods of diagnosis.METHOD: Literature review from peer reviewed Journals cited in PubMed and local journals.   CONCLUSION: Parasites may serve as promoters of cancer in endemic areas of infection.KEY WORD: parasites; cancers; schistosomiasis; liver fluke

Case report of vulvar schwannoma and literature review

Schwannoma is a rare benign encapsulated tumor derived from neural sheath cells. The tumor is more common in the head and neck regions and the extremities. Its location in the vulvovaginal region is a rare phenomenon with a few reported cases worldwide. We report a case of a large vulvar schwannoma occurring in an 18-year-old woman, primigravidae at 35 weeks gestation. The ulcerated tumor mass which measured 10.5 × 7 × 6.5 cm and weighed 249.2 grams was located on the right labium majus with extension into the vagina. The tumor evoked strong immunohistochemical reactivity to S-100. There was no evidence of recurrence after several weeks of excision of the neoplasm