Copie, authenticité et originalité dans les chansonniers de trouvères : un bref panorama

Dans le domaine de la lyrique des trouvères, d’après l’ouvrage bibliographique le plus récent relatif à ce domaine, on peut estimer qu’il existe plus de deux mille chansons et une trentaine de manuscrits que l’on a coutume d’appeler chansonniers. Contrairement aux chansonniers occitans qui sont aujourd’hui plutôt bien connus, ils se distinguent notamment par l’absence de vidas – biographies où la fiction se mêle aisément à la vérité historique – et de razos – circonstances imaginaires dans le..

SF-1 a key player in the development and differentiation of steroidogenic tissues

Since its discovery in the early 1990s, the orphan nuclear receptor SF-1 has been attributed a central role in the development and differentiation of steroidogenic tissues. SF-1 controls the expression of all the steroidogenic enzymes and cholesterol transporters required for steroidogenesis as well as the expression of steroidogenesis-stimulating hormones and their cognate receptors. SF-1 is also an essential regulator of genes involved in the sex determination cascade. The study of SF-1 null mice and of human mutants has been of great value to demonstrate the essential role of this factor in vivo, although the complete adrenal and gonadal agenesis in knock-out animals has impeded studies of its function as a transcriptional regulator. In particular, the role of SF-1 in the hormonal responsiveness of steroidogenic genes promoters is still a subject of debate. This extensive review takes into account recent data obtained from SF-1 haploinsufficient mice, pituitary-specific knock-outs and from transgenic mice experiments carried out with SF-1 target gene promoters. It also summarizes the pros and cons regarding the presumed role of SF-1 in cAMP signalling

Protein kinase C pathway potentiates androgen-mediated gene expression of the mouse was deferens specific aldose reductase-like protein (MVDP)

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Identification of a functional androgen response element in the promoter of the gene for the androgen-regulated aldose reductase-like protein specific to the mouse vas deferens

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Developmental and hormonal regulation of specific proteins in mouse seminal vesicles. Isolation and characterization of genomic and cDNA clones for androgen-regulated secretory protein

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Adrenocorticotropin/3′,5′-Cyclic AMP-Mediated Transcription of the Scavenger akr1-b7 Gene in Adrenocortical Cells Is Dependent on Three Functionally Distinct Steroidogenic Factor-1-Responsive Elements

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A 77-Base Pair LINE-Like Sequence Elicits Androgen-Dependent mvdp/akr1-b7 Expression in Mouse Vas Deferens, But Is Dispensable for Adrenal Expression in Rats 1

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The activation and the spreading of deformation in a fully lamellar Ti-47Al-1Cr-0.2Si Alloy

International audienceThe spreading of deformation in a lamellar Ti-47Al-1Cr-0.2Si alloy deformed under compression is studied at 25°C and 600 °C. This microstructure is largely dominated by twin related variants which are separated by either twin interfaces or thin α2 slabs. The alloy deforms at both temperatures by ordinary dislocations and twins. Deformation in a particular γ variant and its adjacent twin-related variant involves the same kind of glide system, either ordinary dislocations or twins. This property is found to be true for all twin related lamellae. The occurrence of this correlated glide is explained by the introduction of the notion of “pilot” and “driven” orientations. The lamellar orientation in which the operating glide system is activated on the basis of Schmid factor considerations is termed the pilot orientation. It imposes its deformation system on to the twin-related lamella, called the driven orientation whose deformation may not involve the slip system most favoured by the applied stress

Steroidogenic Factor-1 Controls the Aldose Reductase akr1b7 Gene Promoter in Transgenic Mice through an Atypical Binding Site

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