Climate Change, One Health and Mercury

Climate change is occurring on both regional and global scales. The use and global distribution of toxic metals is increasing and affecting environmental, animal and human health as a result of air, water and food contamination. Mercury (Hg) in major forms Hg°, Hg2+ and methyl mercury (CH3Hg+) are increasingly available around the globe. Both metal and organic contaminants are impacting the health of all species on the planet. Mercury is an example of a metal that can cause or aggravate a disease state, for example, diabetes. Habitat stewardship is needed to maintain a healthy system, and selecting a keystone species as a bio indicator to monitor changes in contaminant levels over time and space is essential. Mercury can be used to monitor the flow of toxics through the food system. The structural organization of food webs and their sensitivity to disturbances are relevant to predicting the fate of Hg bioavailability related to climate change. Hg needs to be monitored across many ecosystems because it impacts not only human health but also the health of the plants and animals. Monitoring studies are needed to identify changes related to climate change. Increased precipitation and sea level rise will result in greater mercury mobility into the coastal and terrestrial food webs

The Hardness of Code Equivalence over Fq\mathbf{F}_q and its Application to Code-based Cryptography

International audienceThe code equivalence problem is to decide whether two linear codes over F_q are equivalent, that is identical up to a linear isometry of the Hamming space. In this paper, we review the hardness of code equivalence over F_q due to some recent negative results and argue on the possible implications in code-based cryptography. In particular, we present an improved version of the three-pass identification scheme of Girault and discuss on a connection between code equivalence and the hidden subgroup problem

Shearwater Foraging in the Southern Ocean: The Roles of Prey Availability and Winds

Background Sooty (Puffinus griseus) and short-tailed (P. tenuirostris) shearwaters are abundant seabirds that range widely across global oceans. Understanding the foraging ecology of these species in the Southern Ocean is important for monitoring and ecosystem conservation and management. Methodology/Principal Findings Tracking data from sooty and short-tailed shearwaters from three regions of New Zealand and Australia were combined with at-sea observations of shearwaters in the Southern Ocean, physical oceanography, near-surface copepod distributions, pelagic trawl data, and synoptic near-surface winds. Shearwaters from all three regions foraged in the Polar Front zone, and showed particular overlap in the region around 140°E. Short-tailed shearwaters from South Australia also foraged in Antarctic waters south of the Polar Front. The spatial distribution of shearwater foraging effort in the Polar Front zone was matched by patterns in large-scale upwelling, primary production, and abundances of copepods and myctophid fish. Oceanic winds were found to be broad determinants of foraging distribution, and of the flight paths taken by the birds on long foraging trips to Antarctic waters. Conclusions/Significance The shearwaters displayed foraging site fidelity and overlap of foraging habitat between species and populations that may enhance their utility as indicators of Southern Ocean ecosystems. The results highlight the importance of upwellings due to interactions of the Antarctic Circumpolar Current with large-scale bottom topography, and the corresponding localised increases in the productivity of the Polar Front ecosystem

The complexity of counting edge colorings and a dichotomy for some higher domain Holant problems

We show that an effective version of Siegel’s Theorem on finiteness of integer solutions and an application of elementary Galois theory are key ingredients in a complexity classification of some Holant problems. These Holant problems, denoted by Holant(f), are defined by a symmetric ternary function f that is invariant under any permutation of the κ ≥ 3 domain elements. We prove that Holant(f) exhibits a complexity dichotomy. This dichotomy holds even when restricted to planar graphs. A special case of this result is that counting edge κ-colorings is #P-hard over planar 3-regular graphs for κ ≥ 3. In fact, we prove that counting edge κ-colorings is #P-hard over planar r-regular graphs for all κ ≥ r ≥ 3. The problem is polynomial-time computable in all other parameter settings. The proof of the dichotomy theorem for Holant(f) depends on the fact that a specific polynomial p(x, y) has an explicitly listed finite set of integer solutions, and the determination of the Galois groups of some specific polynomials. In the process, we also encounter the Tutte polynomial, medial graphs, Eulerian partitions, Puiseux series, and a certain lattice condition on the (logarithm of) the roots of polynomials.

Acoustic and electroglottographic voice characteristics in chronic cough and paradoxical vocal fold movement

Objective: Chronic cough (CC) and paradoxical vocal fold movement (PVFM) may be associated with voice problems. Objective acoustic and electroglottographic (EGG) measures have the capacity to delineate these vocal characteristics. This study investigated acoustic and EGG voice features of CC and PVFM. Patients and Methods: Acoustic and EGG findings were compared among 5 groups of participants. The first 3 groups, CC (n = 56), PVFM (n = 8) and combined CC-PVFM (n = 55), included individuals with cough and respiratory symptoms that persisted despite medical treatment. Groups 4 and 5 included individuals with muscle tension dysphonia (n = 25) and healthy controls (n = 27). Results: Participants with CC/PVFM recorded reduced phonation times (p<0.001), greater jitter (p<0.001), reduced harmonic to noise ratio (p = 0.001), reduced phonation range (p = 0.007) and shorter closed phase of vocal fold vibration (p = 0.006) in comparison to healthy controls. Females with CC had reduced fundamental frequency in connected speech (p = 0.009). There was consistent overlap between the participants with CC and those with PVFM. Duration of closed phase and fundamental frequency were lower in the participants with CC and PVFM than in those with muscle tension dysphonia. Conclusion: These results confirm abnormalities in acoustic and EGG voice features in CC and PVFM

Involuntary glottal closure during inspiration in muscle tension dysphonia

Objective/Hypothesis: The purpose of this study was to examine respiratory function in a group of patients with muscle tension dysphonia (MTD) Design: Cross-sectional analytical study. Methods: Participants included 15 people with a diagnosis of MTD referred to speech pathology for management of their voice disorder, fiberoptic evidence of glottal or supraglottic constriction during phonation with or without posterior chink, or bowing combined and deviation in perceptual voice quality. A second group of 15 participants with no history of voice disorder served as healthy controls,. Baseline pulmonary function test measures included forced expiratory volume in the first second (FEV1), FVC, FEF25 to 75, FIF50, FEV1/FVC, ratio and FEF50/FIF50 ratio. Hypertonic saline challenge test measures included FEV1 and FIF50 after provocation, close response slope, and provocation dose. Results: Compared with healthy controls, participants with MTD demonstrated a higher prevalence of glottal constriction during inspiration after provocation with nebulized hypertonic saline as demonstrated by a reduction in FIF50 after the hypertonic saline challenge. There was no significant difference between the MTD and healthy control groups in baseline pulmonary function testing. Participants with MTD demonstrated a higher prevalence than healthy controls of abnormal glottic closure during inspiration similar to paradoxical vocal fold movement (PVFM). This suggests that they either had previously undiagnosed coexisting PVFM or that the condition of MTD could be expanded to include descriptions of aberrant glottic function during respiration. This study enhances the understanding of PVFM and MTD by combining research advances made in the fields of otolaryngology and respiratory medicine

The role of sensory dysfunction in the development of voice disorders, chronic cough and paradoxical vocal fold movement

Sensory function may be important in the pathogenesis of Chronic Cough (CC) and Paradoxical Vocal Fold Movement (PVFM). This paper aims to explore sensory issues related to the pathogenesis, classification, assessment and management of these conditions. Sensory disruption of the vagus nerve can occur through neural plasticity whereby a change occurs in the way a central neuron reacts to an incoming stimulus. Such disruption can be demonstrated through assessment of cough reflex sensitivity and extrathoracic airway hyperresponsiveness both of which may be increased in CC and PVFM. In addition, sensory function may be determined by measuring the laryngeal adductor reflex, however this phenomenon is yet to be explored in CC and PVFM. The similarity in sensory dysfunction between CC and PVFM provides support for a link between the two conditions. There are also similarities in underlying medical conditions and symptom profiles between CC/PVFM and voice disorders such as muscle tension dysphonia. Although coughing and throat clearing may be contributing factors in the development and maintenance of voice disorders, they may occur in response to extrathoracic airway hyperresponsiveness. Dysphonia can occur in CC/PVFM and may improve following behavioural treatment of CC