Flowchart of the study.

<p>Flowchart of the study.</p

Impact of clopidogrel withdrawal and reintroduction on platelet functions.

<p>A: Platelet aggregation response to 20 µM ADP, expressed as maximal aggregation (%). B: VASP phosphorylation level, expressed as the Platelet Reactivity Index (%). D-5: baseline value; Ds: day of surgery; D+7: seven days after surgery, five days after clopidogrel 75 mg resumption.</p

Patients’ characteristics.

<p>Data are presented as the mean value ± SD or number (%) of subjects. RCRI: Revised Cardiac Risk Index; ACE: angiotensin converting enzyme. CI = confidence interval.</p

Impact of aspirin withdrawal and reintroduction on arachidonic acid-induced platelet aggregation.

<p>D-5: baseline value determined during preoperative examination. Ds: day of surgery. D+7: seven days after surgery, five days after aspirin resumption Arachidonic acid was used at 2 mM. Platelet aggregation is expressed as maximal aggregation (%).</p

Platelet-Leukocyte Complex (PLC) levels in the three patient groups.

<p>PLC are expressed as a percentage of total leukocytes. D-5: baseline value for aspirin and clopidogrel groups. Ds: day of surgery, baseline value for the control group. D+7: seven days after surgery, five days after aspirin or clopidogrel 75 mg resumption.</p