Mikrobilääkekulutus Suomessa 2013-2020

Mikrobilääkkeiden kulutuksen seuranta on tärkeä osa mikrobilääkeresistenssin torjuntaa. Tähän työpaperiin on koottu tietoa mikrobilääkkeiden ajallisesta ja alueellisesta kulutuksesta Suomessa. Vaikka kansallisesti mikrobilääkkeiden kulutus on vähenemässä, todetaan alueiden välillä huomattavia eroja. Tämän raportin tarkoitus on auttaa tunnistamaan ne lääkeaineryhmät, joihin olisi syytä kiinnittää huomiota niin kansallisesti kuin eri alueilla ja etsiä keinoja tarpeettoman mikrobilääkekäytön vähentämiseksi

Outbreak of invasive pneumococcal disease among shipyard workers, Turku, Finland, May to November 2019

We report an outbreak of invasive pneumococcal disease and pneumococcal pneumonia among shipyard workers, in Turku, Southwest Finland. In total, 31 confirmed and six probable cases were identified between 3 May and 28 November 2019. Streptococcus pneumoniae serotypes 12F, 4 and 8 were isolated from blood cultures of 25 cases. Occupational hygiene measures and vaccination of ca 4,000 workers are underway to control the outbreak at the shipyard.</p

Practical Approach of the PEST Analysis from the Perspective of the Territorial Intelligence

Considering that steam power was the trigger of the First Industrial Revolution in the 18thcentury and that the discovering new sources of energy, alongside with developing the technologiesrequired to use these new type of fuels in the end of the 19th century was considered the SecondIndustrial Revolution, then the proliferation of the Information Technology and Communicationson one hand, and the development of knowledge workers on the other hand are the main drivers ofthe Third Industrial Revolution, also known as the Knowledge revolution. Digging deeper in the Knowledge Economy, we propose as the subject of this paper and as apart of our research, a theoretical approach in assessing and analyzing a region from theperspective of both territorial intelligence and smart developing

Update on: high but slightly declining COVID-19 vaccine acceptance and reasons for vaccine acceptance, Finland April to December 2020.

We update our previous insights into COVID-19 vaccine acceptance and hesitancy in Finland. Vaccine acceptance increased from 64% (November/December 2020) to 74% (April 2021). However, there was a group of participants that were preferring to wait to get vaccinated ranging from 6% of over-64-years-olds to 29% of under-30-years-olds. The previously identified enablers convenience (below-50-years-olds), worry about severe disease and protection for oneself (above-50-years-olds) were no longer significantly associated with increased vaccine acceptance. Understanding barriers and enablers behind vaccine acceptance is decisive in ensuring a successful implementation of COVID-19 vaccination programs, which will be key to ending the pandemic

High but slightly declining COVID-19 vaccine acceptance and reasons for vaccine acceptance, Finland April to December 2020.

We investigated likelihood to vaccinate and reasons for and against accepting a coronavirus disease 2019 (COVID-19) vaccine among adult residents of Finland. Vaccine acceptance declined from 70% in April to 64% in December 2020. Complacency and worry about side effects were main reasons against vaccination while concern about severe disease was a strong motive for vaccination. Convenience of vaccination and recommendations by healthcare workers were identified as enablers for vaccination among those aged under 50 years. Understanding barriers and enablers behind vaccine acceptance is decisive in ensuring a successful implementation of COVID-19 vaccination programmes, which will be key to ending the pandemic

Numerical analysis of plasmonic metasurfaces for fluorescence enhancement

The paper presents an extensive numerical analysis performed by three-dimensional (3D) simulations using the finite difference in time and space (FDTD) method to identify the optimal geometry, size and configuration of the nano-antennas that constitute a plasmonic metasurface. The aim was to achieve the highest resonance at various wavelengths (NIR-VIS), for local enhancement of the excitation field and collection efficiency of emitted photons. We investigated ten different types of metals, two shapes (disks and U-shape resonators) and various geometrical parameters for the nanoresonators composing the metasurface. The best results for Rhodamine 6G excitation and emission were obtained using silver resonators with 105 nm diameter of the cylinder elements in a rectangular array with a 110 nm period, and with 110 nm long U-shape placed at a period of 40 nm