413 research outputs found

    Incidenteel problemen met oormerken bij schapen

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    Een beperkt aantal meldt veel verwondingen, ontstekingen, slaphangende oren of verlies. De kans op deze problemen neemt af door het oormerk op de juiste plaats in te brengen

    Mogelijkheden aangepast beheer zeedijken met schapen

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    Om meer inzicht te krijgen in het gewenste dijkbeheer voor een voldoende erosiebestendige grasbekleding is in het najaar van 1999 het beheer van de zeedijken geonventariseerd zoals 18 schapenhouders in Zeeland, Noord-Holland en Friesland dat in het voorliggende jaar hadden uitgevoerd

    Oormerkgebruik bij schapen

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    Inventarisatie van gebruikseigenschappen en -probleme

    Oormerkgebruik bij geiten

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    Inventarisatie van gebruikseigenschappen en -probleme

    Estimation of micronutrient intake distributions: development of methods to support food and nutrition policy making

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    Introduction Adequate and safe micronutrient intake is important. Both insufficient and excessive intakes should be prevented as these can be associated with negative health effects. Therefore, the population intake distribution will ideally lay between insufficient and excessive intakes. For the development and evaluation of nutrition and food policy a good estimation of dietary micronutrient intake is of great importance. Aim Three challenges were addressed to improve the estimation of population micronutrient intake distributions: 1) how to estimate current habitual micronutrient intake when (detailed) data are lacking or data from different sources should be combined, 2) how to predict future intakes in order to support policy making, and 3) how to estimate a maximum safe fortification level per food item. The aim of this PhD-thesis is to further develop and apply statistical models which can cope with these challenges. Methods & Results Data from the Dutch National Food Consumption Surveys (DNFCSs) were used to develop and apply statistical models which can cope with the defined challenges. In addition, data from the Dutch food composition database (NEVO) and the Dutch dietary supplement database (NES) were used. Three main methodological improvements have been made. First, the combination of a deterministic approach with probabilistic approaches to be able to take into account uncertainty and variability were needed. This method was applied to estimate habitual iodine and salt intake distributions. From DNFCSs no detailed information was available on the discretionary use of (iodized) salt and no up to date information was available on the use of iodized salt in industrially processed foods. Estimates of the proportion of the population discretionarily using (iodized) salt and the proportion of industrially processed foods applying iodized salt were obtained from other data sources. The model accurately estimates habitual iodine and salt intake distributions when compared with studies measuring urinary iodine and sodium excretion. Additionally a framework was developed to simulate the habitual intake distribution for potential scenarios of future fortification strategies. Within this framework, deterministic and probabilistic approaches were combined when uncertainty or variability had to be taken into account. This framework was illustrated by the estimation of habitual folate-equivalent intake for different scenarios of mandatory or voluntary fortification with folic acid. Further this framework was applied to estimate the habitual iodine intake for several potential changes in the Dutch iodine policy and also for several scenarios of salt reduction strategies. A second methodological improvement was the development of a new statistical model to estimate habitual total micronutrient intake aggregated from food and dietary supplements. Within this 3-part model, habitual intake is estimated separately for a) intake from food for non-users of dietary supplements, b) intake from food for users of dietary supplements, and c) intake from dietary supplements for users only. Habitual total intake for the whole population was obtained by combination of the three separate habitual intake distributions (‘first shrink then add’). This 3-part model was illustrated by vitamin D intake for young children. With a more simple ‘first add then shrink’ approach the estimation of habitual total vitamin D intake distribution may give inconsistent results for the distribution of intake from foods and dietary supplements combined as compared to the intake from food only. In addition, this more simple approach may not be able to cope with multi modal distributions. With the newly developed model this inconsistency problem was solved and the multi-modal shape of the distribution as observed in the ‘raw’ data was preserved. Third, a model calculating the maximum safe fortification level per 100 kcal of a food was developed for the Dutch situation. By considering the tolerable upper intake level and reasonable high micronutrient intakes from food and dietary supplements, the ‘free space’ for voluntary fortification was calculated. This amount was divided over the amount of energy intake that can and may be fortified. The model was applied to derive safe maximum fortification levels for vitamin A, D, and folic acid. Based on these results the risk manager decided to legally allow voluntary fortification with vitamin D and folic acid up to a maximum level of 4.5 and 100 μg/100 kcal respectively. Conclusion The methodological improvements have resulted in higher accuracy for estimations of habitual intake distributions, which are essential for nutritional and food policy making. Furthermore, scenario analyses provide (under specific conditions) quantitative insight into proposed changes or areas such as maximum safe fortification levels. Several results and methods described are currently being used in research to assist Dutch and European food and nutrition policy making, which shows these methodologies are of immediate value to the practice of policy development and support. </p

    Reduction of salt: will iodine intake remain adequate in The Netherlands?

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    Salt is the main vehicle for iodine fortification in The Netherlands. A reduction in salt intake may reduce the supply of iodine. Our aim was to quantify the effect of salt reduction on the habitual iodine intake of the Dutch population and the risk of inadequate iodine intake. We used data of the Dutch National Food Consumption Survey (1997–8) and an update of the food composition database to estimate habitual salt and iodine intake. To take into account uncertainty about the use of iodised salt (industrial and discretionary) and food supplements, a simulation model was used. Habitual iodine and salt intakes were simulated for scenarios of salt reduction and compared with no salt reduction. With 12, 25 and 50 % salt reduction in industrially processed foods, the iodine intake remained adequate for a large part of the Dutch population. For the extreme scenario of a 50 % reduction in both industrially and discretionary added salt, iodine intake might become inadequate for part of the Dutch population (up to 10 %). An increment of the proportion of industrially processed foods using iodised salt or a small increase in iodine salt content will solve this. Nevertheless, 8–35 % of 1- to 3-year-old children might have iodine intakes below the corresponding estimated average requirement (EAR), depending on the salt intake scenario. This points out the need to review the EAR value for this age group or to suggest the addition of iodine to industrially manufactured complementary food

    NHI 2.1 Veranderingen in NHI

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    Dit document is een concept en uitsluitend bedoeld voor discussiedoeleinden. Een impuls is gegeven aan het verbeteren van het nationaal hydrologisch instrumentarium, NHI 2.0. NHI 2.0 voldeed in 2010 nog niet volledig aan de wensen van RWS. In 2010 hebben twee processen plaatsgevonden, die tot meer inzicht hebben geleid in de prestaties van het NHI. Ten eerste de regionale toetsing van het NHI, onder andere door STOWA, en ten tweede het gebruik van NHI in diverse regionale en landelijke studies voor Zoetwaterverkenning (ZWV). Als gevolg hiervan zijn in NHI 2.1, in opdracht van de RWS Waterdienst, veel verbeteringen doorgevoerd

    Wederom goede aflamresultaten in het Low-inputsysteem!

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    Het Low-input systeem, gekenmerkt door het ontbreken van huisvesting en het niet verstrekken van krachtvoer, heeft wederom goede aflamresultaten behaald

    Low-inputsysteem schapen: de groei van gras en lammeren in 1998

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    De groei van lammeren in dit systeem is vooral afhankelijk van de graslandproductie, de kwaliteit van het gras en de gezondheidsstatus van de lammeren

    Concomitant endocarditis and spondylodiscitis due to coagulase-negative Staphylococci and a review of the literature

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    Background: Coagulase-negative staphylococci (CoNS) are part of the normal skin flora. Although CoNS are generally considered as low pathogenic microorganisms, they can cause serious infections, particularly in the context of foreign body material. Case report: Here we present two cases of concomitant infectious endocarditis and spondylodiscitis; one caused by S. epidermidis, the other by S. haemolyticus. Additionally, we reviewed the literature for previously reported cases of concomitant endocarditis and spondylodiscitis due to CoNS. Conclusion: In patients with back pain and a cardiac device in situ, CoNS should be considered as causative pathogens for possible endocarditis and/or spondylodiscitis, and should not be regarded as contamination.</p
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