Sobrepeso e ingesta alimentaria en escolares de la zona Costa del Estado de Oaxaca

Introduction: Overweight and obesity are a public health concern with particular importance in childhood, since in this day, habits are established that condition food intake. Mexico occupies the first place in childhood obesity, in Oaxaca the jurisdictions with the highest index are la Costa, Tuxtepec, and el Istmo. The city of Puerto Escondido of Oaxaca coast, has social and cultural characteristics that place it in a context vulnerable. Objective: To describe the prevalence of overweight, obesity and food intake in children from 9 to 13 years old in an urban elementary school in the city of Puerto Escondido. Methodology: Descriptive study-transversal with population of 203 students from 9 to 13 years old. The procedure included a sample of 133 students to whom a personal data card was applied, a questionnaire on food intake and anthropometric measurements for the calculation of body mass index (BMI). Results: 50.4% of the students were boys and 49.6% were girls. In respect to the BMI for age, more than 50% had a weight above normal: 32.33% with overweight and 22.56% with obesity. 75.19% of students have a normal overeating, which indicates that they are at the limit between maintaining a healthy body weight. Conclusion: The prevalence of overweight and obesity continues to increase and is marked as age increases; the psychological factors have an important impact on the dietary intake of students.Introducción: El sobrepeso y la obesidad son un problema de salud pública en la niñez, dado que en esta época se establecen hábitos que condicionan la ingesta alimentaria. México ocupa el primer lugar a nivel mundial en obesidad infantil; en Oaxaca las jurisdicciones con mayor índice son la Costa, Tuxtepec y el Istmo. La ciudad de Puerto Escondido de la región Costa de Oaxaca, posee características sociales y culturales que la sitúan en un contexto vulnerable. Objetivo: Describir la prevalencia de sobrepeso, obesidad e ingesta alimentaria en niños y niñas de 9 a 13 años de una escuela primaria urbana de la Ciudad de Puerto Escondido. Metodología: Estudio descriptivo-transversal con una población de 203 escolares de 9 a 13 años. El procedimiento incluyó una muestra de 133 escolares a los que se aplicaron una Cédula de Datos Personales, Cuestionario de Sobreingesta Alimentaria y medidas antropométricas para el calculó de Índice de Masa Corporal (IMC). Resultados: El 50.4% de los escolares fueron niños y 49.6% niñas. Respecto al IMC para la edad, más del 50% presentaron un peso por arriba de lo normal: 32.33% con sobrepeso y 22.56% con obesidad. El 75.19% de los escolares tiene una sobreingesta normal, lo que indica que se encuentran en el límite entre conservar un peso corporal sano. Conclusión: La prevalencia de sobrepeso y obesidad continúa en incremento y es marcada conforme aumenta la edad; los factores psicológicos repercuten de forma importante en la ingesta alimentaria de los escolares

Sobrepeso e ingesta alimentaria en escolares de la zona Costa del Estado de Oaxaca

Introducción: El sobrepeso y la obesidad son un problema de salud pública en la niñez, dado que en esta época se establecen hábitos que condicionan la ingesta alimentaria. México ocupa el primer lugar a nivel mundial en obesidad infantil; en Oaxaca las jurisdicciones con mayor índice son la Costa, Tuxtepec y el Istmo. La ciudad de Puerto Escondido de la región Costa de Oaxaca, posee características sociales y culturales que la sitúan en un contexto vulnerable. Objetivo: Describir la prevalencia de sobrepeso, obesidad e ingesta alimentaria en niños y niñas de 9 a 13 años de una escuela primaria urbana de la Ciudad de Puerto Escondido. Metodología: Estudio descriptivo-transversal con una población de 203 escolares de 9 a 13 años. El procedimiento incluyó una muestra de 133 escolares a los que se aplicaron una Cédula de Datos Personales, Cuestionario de Sobreingesta Alimentaria y medidas antropométricas para el calculó de Índice de Masa Corporal (IMC). Resultados: El 50.4% de los escolares fueron niños y 49.6% niñas. Respecto al IMC para la edad, más del 50% presentaron un peso por arriba de lo normal: 32.33% con sobrepeso y 22.56% con obesidad. El 75.19% de los escolares tiene una sobreingesta normal, lo que indica que se encuentran en el límite entre conservar un peso corporal sano. Conclusión: La prevalencia de sobrepeso y obesidad continúa en incremento y es marcada conforme aumenta la edad; los factores psicológicos repercuten de forma importante en la ingesta alimentaria de los escolares.   Abstract Introduction: Overweight and obesity are a public health concern with particular importance in childhood, since in this day, habits are established that condition food intake. Mexico occupies the first place in childhood obesity, in Oaxaca the jurisdictions with the highest index are la Costa, Tuxtepec, and el Istmo. The city of Puerto Escondido of Oaxaca coast, has social and cultural characteristics that place it in a context vulnerable. Objective: To describe the prevalence of overweight, obesity and food intake in children from 9 to 13 years old in an urban elementary school in the city of Puerto Escondido. Methodology: Descriptive study-transversal with population of 203 students from 9 to 13 years old. The procedure included a sample of 133 students to whom a personal data card was applied, a questionnaire on food intake and anthropometric measurements for the calculation of body mass index (BMI). Results: 50.4% of the students were boys and 49.6% were girls. In respect to the BMI for age, more than 50% had a weight above normal: 32.33% with overweight and 22.56% with obesity. 75.19% of students have a normal overeating, which indicates that they are at the limit between maintaining a healthy body weight. Conclusion: The prevalence of overweight and obesity continues to increase and is marked as age increases; the psychological factors have an important impact on the dietary intake of students

X chromosome inactivation does not necessarily determine the severity of the phenotype in Rett syndrome patients

WOS: 000481590200024PubMed ID: 31427717Rett syndrome (RTT) is a severe neurological disorder usually caused by mutations in the MECP2 gene. Since the MECP2 gene is located on the X chromosome, X chromosome inactivation (XCI) could play a role in the wide range of phenotypic variation of RTT patients; however, classical methylation-based protocols to evaluate XCI could not determine whether the preferentially inactivated X chromosome carried the mutant or the wild-type allele. Therefore, we developed an allele-specific methylation-based assay to evaluate methylation at the loci of several recurrent MECP2 mutations. We analyzed the XCI patterns in the blood of 174 RTT patients, but we did not find a clear correlation between XCI and the clinical presentation. We also compared XCI in blood and brain cortex samples of two patients and found differences between XCI patterns in these tissues. However, RTT mainly being a neurological disease complicates the establishment of a correlation between the XCI in blood and the clinical presentation of the patients. Furthermore, we analyzed MECP2 transcript levels and found differences from the expected levels according to XCI. Many factors other than XCI could affect the RTT phenotype, which in combination could influence the clinical presentation of RTT patients to a greater extent than slight variations in the XCI pattern.Spanish Ministry of Health (Instituto de Salud Carlos III/FEDER) [PI15/01159]; Crowdfunding program PRECIPITA, from the Spanish Ministry of Health (Fundacion Espanola para la Ciencia y la Tecnologia); Catalan Association for Rett Syndrome; Fondobiorett; Mi Princesa RettWe thank all patients and their families who contributed to this study. The work was supported by grants from the Spanish Ministry of Health (Instituto de Salud Carlos III/FEDER, PI15/01159); Crowdfunding program PRECIPITA, from the Spanish Ministry of Health (Fundacion Espanola para la Ciencia y la Tecnologia); the Catalan Association for Rett Syndrome; Fondobiorett and Mi Princesa Rett