Synthesis and antimicrobial activity of pyrimidinylsulfamoyl azolylbenzamides

907-915A variety of sulfonamide linked azolyl pyrimidines have been prepared and studied for their antimicrobial activity. The chloro and nitro substituted thiazolyl pyrimidines (12c and 12e) display potential antibacterial activity against Bacillus subtilis. The chloro, bromo and nitro substituted imidazolyl pyrimidines (13c, 13d and 13e) show potential antifungal activity against Aspergillus niger

Synthesis of a new class of bis heterocycles

1295-1300A variety of bis heterocycles-oxazolyl / thiazolyl / imidazolyl pyrroles and pyrazoles have been prepared adopting 1,3-dipolar cycloaddition of tosylmethyl isocyanide and diazomethane to oxazolyl / thiazolyl / imidazolyl acrylamides

Synthesis and antimicrobial activity of bisazolylsulfonyl amines

1376-1383A variety of bisazolylsulfonyl amines have been prepared from azolylsulfonyl chlorides and azolylsulfonamides and their antimicrobial activity studied. The chloro substituted bisthiazolylsulfonyl amines exhibit pronounced antibacterial activity against B. subtilis. The unsubstituted and chloro substituted bisimidazolylsulfonyl amines show promising antifungal activity against A. niger

Heterocyclization reactions of ketene dithiolates

665-670The reaction of ketene dithiolates in the presence of K2CO3 lead to bisthioalkylated products and thienothiophene derivatives depending on the strength of the base. The 1,5-diamino groups in thienothiophene compounds are subjected to heterocyclization under PTC conditions to get a variety of fused heterocycles