2 research outputs found
Radio-guided occult lesion localization for nonpalpable suspicious breast lesions: A novel technique
Background : Breast screening programs and increased self-awareness has
led to increased identification of early breast cancers. Up to 25% of
mammographicaly identified lesions are nonpalpable, which require a
precise technique to localize and excise completely. Radio-guided
occult lesion localization (ROLL) is a technique, which uses hand held
gamma probe to accurately localize and completely excise occult beast
lesions. ROLL can also be combined with sentinel lymph node biopsy
(SLNB) for early breast cancers. This is a minimally invasive approach
with least morbidity and better patient compliance. Materials and
Methods : 25 cases underwent ROLL for nonpalpable breast lesions. 99m
Tc-sulphur colloid was injected into the center of the lesion under
ultrasound guidance preoperatively. No guidewire localization was
performed. Under general anesthesia, surgical excision of the lesion
was carried out using the hand-held gamma probe. Fifteen patients were
diagnosed with early breast cancer with clear margin status. These
patients also underwent SLNB at the same procedure. Results : Fifteen
out of 25 cases were found to harbor invasive breast cancer. The
pathological margins were clear of tumor in all of these patients. The
sentinel node was identified in all cases. In four out of the 15 cases,
sentinel node harbored occult metastases. Conclusion : ROLL is a
useful method for precise, three-dimensional localization of impalpable
breast tumors with results comparable to those achieved by surgery of
palpable lesions. Furthermore, ROLL is feasible in connection with
sentinel node biopsy in the same setting. It is performed as a day-care
procedure with good cosmesis
Radio-guided occult lesion localization for nonpalpable suspicious breast lesions: A novel technique
Background : Breast screening programs and increased self-awareness has
led to increased identification of early breast cancers. Up to 25% of
mammographicaly identified lesions are nonpalpable, which require a
precise technique to localize and excise completely. Radio-guided
occult lesion localization (ROLL) is a technique, which uses hand held
gamma probe to accurately localize and completely excise occult beast
lesions. ROLL can also be combined with sentinel lymph node biopsy
(SLNB) for early breast cancers. This is a minimally invasive approach
with least morbidity and better patient compliance. Materials and
Methods : 25 cases underwent ROLL for nonpalpable breast lesions. 99m
Tc-sulphur colloid was injected into the center of the lesion under
ultrasound guidance preoperatively. No guidewire localization was
performed. Under general anesthesia, surgical excision of the lesion
was carried out using the hand-held gamma probe. Fifteen patients were
diagnosed with early breast cancer with clear margin status. These
patients also underwent SLNB at the same procedure. Results : Fifteen
out of 25 cases were found to harbor invasive breast cancer. The
pathological margins were clear of tumor in all of these patients. The
sentinel node was identified in all cases. In four out of the 15 cases,
sentinel node harbored occult metastases. Conclusion : ROLL is a
useful method for precise, three-dimensional localization of impalpable
breast tumors with results comparable to those achieved by surgery of
palpable lesions. Furthermore, ROLL is feasible in connection with
sentinel node biopsy in the same setting. It is performed as a day-care
procedure with good cosmesis