31 research outputs found

    Ocimum sanctum: a review on the pharmacological properties

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    Herbal medicine, the backbone of traditional medicine in many countries have played an important role in curing the diseases of humans since ancient time. Medicinal plants are great source of bioactive compounds and chemical structures that have potential beneficial effects. The present review compiles information on ethnopharmacologically useful information and pharmacological properties of Ocimum sanctum. Ocimum sanctum (OS) has many medicinal properties like antioxidant, antidiabetic, antiulcer, anticancer, antibacterial, antifungal and other. The phytochemicals compounds of Ocimum, alkaloids, flavonoids, phenolics, essential oils, tannins and saponins play an important role in herbal medicine. Bioactive compounds of Ocimum responsible for its various medicinal properties and their effects at the molecular level need to be investigated in more detail. Furthermore, pharmacological properties of bioactive compounds in Ocimum sanctum are required to confirm the ethnomedicinal claims of Ocimum sanctum for pharmaceutical therapeutic applications

    INTERNATIONAL JOURNAL OF PHARMACY & LIFE SCIENCES Screening of potential efficacy of dietary ginger on ethanol induced oxidative stress in rat cardiac tissue: A study on changes in basic metabolic profiles

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    Abstract The present study was premeditated to examine the possible mechanisms where by ginger (Zingiber officinale) could protect cardiac tissue from alcohol toxicity in rats. The carbohydrate metabolic profiles like total carbohydrates, pyruvate, total proteins, free amino acids and lactate levels were measured in heart tissue. The total carbohydrates, pyruvate, and total proteins were significant declined while free amino acids, lactate levels were significant increased in alcohol intoxicated rats. Whereas with ginger (200 mg/kg body weight) treatment shown significant increase in the total carbohydrates, total proteins and pyruvate levels, whereas free amino acids, lactate levels were significant drop in the cardiac tissues. From the present study, we conclude that ginger protects the heart tissue from alcohol toxicity in rats, this may be due to the presence of many bioactive compounds in ginger

    Structural, optical and magnetic properties of Cu doped CeO2 nano powders synthesized by solid state reaction

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    In this research work, the structural, optical, and magnetic properties of Ce _1−x Cu _x O nanoparticles have been reported. Solid state reaction technique was employed to synthesize the nanoparticle samples. The synthesized materials were analysed structural properties from x-ray diffraction (XRD) observed that the crystallite size increased from16.9 nm to 40.43 nm and the lattice constant increased with increase of Cu doping concentration, and the structural properties after doping confirm the absence of other phase and synthesized samples had a cubic structure. Using SEM and EDAX, the nanoparticles surface morphology and elemental composition in investigated. The nanoparticles have a spherical shape and approximately the expected stoichiometric ratio. The optical band gap of copper doped cerium oxide nanoparticles is calculated and found the band gap decreased with increased dopant concentration. Ce _1−x Cu _x O nanoparticles using photoluminescence (PL) analysis at excitation wavelengths of 350 nm revealed emissions of the violet, blue, green, and red regions within the range of 350–700 nm. Vibrating sample magnetometer was found that the samples were room temperature ferromagnetic in nature and strength of magnetic moment increased with increase of doping concentration

    Enantioselective First Total Syntheses of 2-(Formylamino)trachyopsane and ent-2-(Isocyano)trachyopsane via a Biomimetic Approach

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    A biomimetic rearrangement of an isotwistane to a tricyclo[4.3.1.0(3,8)]decane has been employed as the key step for the enantioselective first total syntheses of the marine sesquiterpenes 2-(formylamino)trachyopsane and ent-2-(isocyano)trachyopsanes ascertaining the biogenetic relationship between the marine sesquiterpenes neopupukeananes and trachyopsanes

    Optimal production planning under resource constraints

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    966-969Production planning is meant to arrive at the framework of manufacturing operations during the period planned. This paper addresses the solution for finding an optimal production planning to minimize the total cost under the resource constraints taking overtime and subcontracting costs. A mathematical model is formulated and Genetic algorithms are implemented in constrained optimization to arrive an optimal solution

    Two step growth mechanism of Cu2ZnSnS4 thin films

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    Cu2ZnSnS4 (CZTS) semiconductor is rapidly emerging as the best absorber layer for next generation solar photovoltaics. Its cost effectiveness, environment-friendly nature, wide presence of chemical constituents in nature and high absorption coefficient with suitable energy band gap for effective utilization of solar spectrum makes it a viable alternative. The present work summarizes the preparation of CZTS films through a two-step process consisting of co-sputtered metallic precursors on glass substrates kept at 230 degrees C Followed by sulfurization for 2 h in the ambience of elemental sulfur vapor at different temperatures ranging from 300 to 550 degrees C. The X-ray diffraction (XRD) and Raman analysis make it explicit that the sulfurization temperature has significant impact on reaction mechanism resulting in various hi-metallic, mono and binary metal sulfides. The diffraction pattern noticed at 500 degrees C corresponding to (112), (220) and (312) planes confirms the single phase CZTS as evidenced by weak and strong Raman modes at 285, 337 and 352 cm(-1), The transmittance and reflectance measurements of optimized CZTS films revealed that the films have an energy band gap of similar to 1.56 eV. The optimized films were characterized by scanning electron microscopy (SEM) attached with EDS to know the morphological features and elemental quantification. The single phase CZTS films have exhibited p-type conductivity with sheet resistance similar to 6.8 x 10(3) Omega/sq., carrier concentration similar to 9.1 x 10(17) cm(-3) and hole mobility similar to 16.6 cm(2)V(-1) s(-1)
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