6 research outputs found
Study of a spherical photonic crystal with conducting nano shell and a nano particle core
- Author
- Publication venue
- Universidad de Guadalajara (UDG)
- Publication date
- 01/01/2010
- Field of study
No full textWe discuss the effects of a 3D Metallo Dielectric Photonic Crystal with both a metallic core and a metallic shell as basic elements. We discuss the formed cavity as well as the dielectric stack in a structured sphere. © 2010 Optical Society of America
Heterogenous Distribution of MTHFR Gene Variants among Mestizos and Diverse Amerindian Groups from Mexico
- Author
- A Binia
- A Moreno-Estrada
- Angélica Martínez-Hernández
- B Wilcken
- BD O'Fallon
- Beatríz E. Sánchez-Hernández
- Cecilia Contreras-Cubas
- EA Varga
- EJ Vallender
- Elvia C. Mendoza-Caamal
- Emilio J. Córdova
- Eva Gabriela Salas-Bautista
- Federico Centeno-Cruz
- Francisco Barajas-Olmos
- G Ordonez
- Gabriela Ortiz-Cruz
- GR Abecasis
- H Rangel-Villalobos
- Humberto García-Ortiz
- I Silva-Zolezzi
- I Weisberg
- IP Davalos
- J Gelineau-van Waes
- J Valdes-Hernandez
- JC Barrett
- José Concepción Jiménez-López
- Juan Carlos Fernández-López
- L Gonzalez-Herrera
- LD Botto
- Lorena Orozco
- M Melnick
- Miguel Cid
- MV Reddy
- N Fodil-Cornu
- NA Johnson
- NM van der Put
- NM van der Put
- OM Mutchinick
- Osvaldo M. Mutchinick
- P Canto
- P Frosst
- P Goyette
- R de Franchis
- R Juarez-Velazquez
- R Kosoy
- R Rubi-Castellanos
- RM Gueant-Rodriguez
- RV Alluri
- S Purcell
- S Wang
- SA Missmer
- STD Consortium
- V Antonio-Vejar
- WF Marasas
- YI Kim
- Yolanda Saldaña-Alvarez
- Zoha Kibar
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- Field of study
No full textAlbiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial
- Author
- Abbas J.
- Abraham S.
- Ackert J.
- Adams P.
- Aggarwala G.
- Aher N.
- Ahlqvist J.
- Ahn C. W.
- Akers T.
- Akhras R.
- Akhter F.
- Aksentyev S.
- Al Kawas F.
- Alexander K.
- Althouse D.
- Altobelli D.
- Alvarisqueta A.
- Ambrosy A.
- Andersen J.
- Andersen U.
- Anderson M.
- Anglade M.
- Arbanil H.
- Arciszewska M.
- Argoud G.
- Ariani M.
- Ashdji R.
- Avogaro A.
- Avramidis I.
- Axthelm C.
- Aye M.
- Babi C.
- Bachus E.
- Baik S. -H.
- Bailey M.
- Bakhtari L.
- Baksi A.
- Balasubramani M.
- Baldovino J.
- Banach M.
- Banerjee S.
- Bartlett A.
- Bartone S.
- Baum H.
- Bays H.
- Bazhan L.
- Beasley R.
- Beaudry Y.
- Beaulieu G.
- Beboso R.
- Bedard J.
- Beijerbacht H. P.
- Belfort de Aguiar R.
- Benjamin S.
- Berger D.
- Berlingieri J.
- Berndtsson Blom K.
- Besada D.
- Bethel M. A.
- Bhagwat R.
- Bhargava A.
- Bhosale A.
- Bieler T.
- Bijata-Bronisz R.
- Birkeland K.
- Birkenfeld A.
- Blagden M.
- Bloomfield G.
- Bode B.
- Boemi M.
- Bonadonna R.
- Bondar I.
- Bott J.
- Bousboulas S.
- Boye A.
- Bratcher C.
- Breneman J.
- Briskin T.
- Bristianou M.
- Brockmyre A.
- Bronnum-Schou J.
- Broughton R.
- Brown J.
- Brown K.
- Brychta T.
- Budhraja M.
- Bull G.
- Bundy C.
- Burgess L.
- Busch K.
- Caca K.
- Cadinot D.
- Calderon J.
- Calella P.
- Califf R. M.
- Calvo Gomez C.
- Camacho L.
- Cannon K.
- Cano Rodriguez I.
- Cantero M. C.
- Carr J.
- Casson E.
- Castano P.
- Castro Conde A.
- Cathcart H.
- Cavale A.
- Cech V.
- Cequier Fillat A.
- Cervantes-Escarcega J. -L.
- Cha B. -S.
- Chau T.
- Chaykin L.
- Chehayeb R.
- Chen D.
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- Cheung D.
- Cheung S.
- Chevts J.
- Chiang C. -E.
- Childress R.
- Christian T.
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- Cohen A.
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- Condit J.
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- Damyanova V.
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- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2018
- Field of study
No full textBackground: Glucagon-like peptide 1 receptor agonists differ in chemical structure, duration of action, and in their effects on clinical outcomes. The cardiovascular effects of once-weekly albiglutide in type 2 diabetes are unknown. We aimed to determine the safety and efficacy of albiglutide in preventing cardiovascular death, myocardial infarction, or stroke. Methods: We did a double-blind, randomised, placebo-controlled trial in 610 sites across 28 countries. We randomly assigned patients aged 40 years and older with type 2 diabetes and cardiovascular disease (at a 1:1 ratio) to groups that either received a subcutaneous injection of albiglutide (30–50 mg, based on glycaemic response and tolerability) or of a matched volume of placebo once a week, in addition to their standard care. Investigators used an interactive voice or web response system to obtain treatment assignment, and patients and all study investigators were masked to their treatment allocation. We hypothesised that albiglutide would be non-inferior to placebo for the primary outcome of the first occurrence of cardiovascular death, myocardial infarction, or stroke, which was assessed in the intention-to-treat population. If non-inferiority was confirmed by an upper limit of the 95% CI for a hazard ratio of less than 1·30, closed testing for superiority was prespecified. This study is registered with ClinicalTrials.gov, number NCT02465515. Findings: Patients were screened between July 1, 2015, and Nov 24, 2016. 10 793 patients were screened and 9463 participants were enrolled and randomly assigned to groups: 4731 patients were assigned to receive albiglutide and 4732 patients to receive placebo. On Nov 8, 2017, it was determined that 611 primary endpoints and a median follow-up of at least 1·5 years had accrued, and participants returned for a final visit and discontinuation from study treatment; the last patient visit was on March 12, 2018. These 9463 patients, the intention-to-treat population, were evaluated for a median duration of 1·6 years and were assessed for the primary outcome. The primary composite outcome occurred in 338 (7%) of 4731 patients at an incidence rate of 4·6 events per 100 person-years in the albiglutide group and in 428 (9%) of 4732 patients at an incidence rate of 5·9 events per 100 person-years in the placebo group (hazard ratio 0·78, 95% CI 0·68–0·90), which indicated that albiglutide was superior to placebo (p<0·0001 for non-inferiority; p=0·0006 for superiority). The incidence of acute pancreatitis (ten patients in the albiglutide group and seven patients in the placebo group), pancreatic cancer (six patients in the albiglutide group and five patients in the placebo group), medullary thyroid carcinoma (zero patients in both groups), and other serious adverse events did not differ between the two groups. There were three (<1%) deaths in the placebo group that were assessed by investigators, who were masked to study drug assignment, to be treatment-related and two (<1%) deaths in the albiglutide group. Interpretation: In patients with type 2 diabetes and cardiovascular disease, albiglutide was superior to placebo with respect to major adverse cardiovascular events. Evidence-based glucagon-like peptide 1 receptor agonists should therefore be considered as part of a comprehensive strategy to reduce the risk of cardiovascular events in patients with type 2 diabetes. Funding: GlaxoSmithKline
Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial
- Author
- Abbas J
- Abraham S
- Ackert J
- Adams P
- Aggarwala G
- Aher N
- Ahlqvist J
- Ahn Cw
- Akers T
- Akhras R
- Akhter F
- Aksentyev S
- Al Kawas F
- Alexander K
- Althouse D
- Altobelli D
- Alvarisqueta A
- Ambrosy A
- Andersen J
- Andersen U
- Anderson M
- Anglade M
- Arbanil H
- Arciszewska M
- Argoud G
- Ariani M
- Ashdji R
- Avogaro A
- Avramidis I
- Axthelm C
- Aye M
- Babi C
- Bachus E
- Baik S-
- Bailey M
- Bakhtari L
- Baksi A
- Balasubramani M
- Baldovino J
- Banach M
- Banerjee S
- Bartlett A
- Bartone S
- Baum H
- Bays H
- Bazhan L
- Beasley R
- Beaudry Y
- Beaulieu G
- Beboso R
- Bedard J
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- Zeller-Stefan H
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- Publication venue
- Publication date
- 01/01/2018
- Field of study
No full textGlucagon-like peptide 1 receptor agonists differ in chemical structure, duration of action, and in their effects on clinical outcomes. The cardiovascular effects of once-weekly albiglutide in type 2 diabetes are unknown. We aimed to determine the safety and efficacy of albiglutide in preventing cardiovascular death, myocardial infarction, or stroke
Genitourinary Pathology (Including Adrenal Gland)
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- YM Choi
- Z Jiang
- Z Kaleem
- Z Kirkali
- Z Lane
- Z Loncar
- Publication venue
- Cham
- Publication date
- 30/01/2020
- Field of study
No full textOur aims in constructing the Genitourinary Pathology chapter are to describe neoplasms of the adrenal gland, urothelial tract, kidney, penis, prostate, and testis in a manner that is both useful for the practicing surgical pathologist and that may be used as a reference for all students of urologic pathology. Whereas the text and figures describe the salient morphologic, immunohistochemical, and molecular attributes for each tumor type and encompass the latest classification schemes, the narrative integrates the clinical and pathological findings that are commonly encountered during surgical pathology sign-out of these cases. Accordingly, it is our hope that this chapter will serve as a guide for both general and subspecialized pathologists in contemporary practice
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
- Author
- Abdelmohsen Kotb
- Abe Akihisa
- Abedin Md Joynal
- Abeliovich Hagai
- Adachi Hiroaki
- Adams Christopher M.
- Adams Peter D.
- Adeli Khosrow
- Adhihetty Peter J.
- Adler Sharon G.
- Agam Galila
- Agarwal Rajesh
- Aghi Manish K.
- Agnello Maria
- Agostinis Patrizia
- Aguilar Patricia V.
- Aguirre-Ghiso Julio
- Airoldi Edoardo M.
- Ait-Si-Ali Slimane
- Akematsu Takahiko
- Akporiaye Emmanuel T.
- Al-Rubeai Mohamed
- Albaiceta Guillermo M.
- Albanese Chris
- Albani Diego
- Albert Matthew L.
- Aldudo Jesus
- Alguel Hana
- Alirezaei Mehrdad
- Alloza Iraide
- Almasan Alexandru
- Almonte-Beceril Maylin
- Alnemri Emad S.
- Alonso Covadonga
- Altan-Bonnet Nihal
- Altieri Dario C.
- Alvarez Silvia
- Alvarez-Erviti Lydia
- Alves Sandro
- Amadoro Giuseppina
- Amano Atsuo
- Amantini Consuelo
- Ambrosio Santiago
- Amelio Ivano
- Amer Amal O.
- Amessou Mohamed
- Amon Angelika
- An Zhenyi
- Ana Gonzalez-Polo Rosa
- Anania Frank A.
- Andersen Stig U.
- Andley Usha P.
- Andreadi Catherine K.
- Andrieu-Abadie Nathalie
- Anel Alberto
- Ann David K.
- Anoopkumar-Dukie Shailendra
- Antonioli Manuela
- Aoki Hiroshi
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- Aranda Agustin
- Araya Jun
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- Armstrong Jane L.
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- Pimentel-Muinos Felipe X.
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- Sun Fang-Lin
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- Xu Congfeng
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- Yan Bo
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- Yang Dun-Sheng
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- Yeganeh Behzad
- Yeh Elizabeth S.
- Yeyati Patricia L.
- Yi Fan
- Yi Long
- Yin Xiao-Ming
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- Yoo Young Hyun
- Yoon Seung-Yong
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- Yoshimori Tamotsu
- Young Ken H.
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- Yu Li
- Yu W. Haung
- Yu Xiao-Fang
- Yu Zhengping
- Yuan Junying
- Yuan Zhi-Min
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- Yue Jianbo
- Yue Zhenyu
- Zacks David N.
- Zacksenhaus Eldad
- Zaffaroni Nadia
- Zaglia Tania
- Zakeri Zahra
- Zecchini Vincent
- Zeng Jinsheng
- Zeng Min
- Zeng Qi
- Zervos Antonis S.
- Zhang Donna D.
- Zhang Fan
- Zhang Guo
- Zhang Guo-Chang
- Zhang Hao
- Zhang Hong
- Zhang Hong
- Zhang Hongbing
- Zhang Jian
- Zhang Jian
- Zhang Jiangwei
- Zhang Jianhua
- Zhang Jing-pu
- Zhang Li
- Zhang Lin
- Zhang Lin
- Zhang Long
- Zhang Ming-Yong
- Zhang Xiangnan
- Zhang Xu Dong
- Zhang Yan
- Zhang Yang
- Zhang Yanjin
- Zhang Yingmei
- Zhang Yunjiao
- Zhao Mei
- Zhao Wei-Li
- Zhao Xiaonan
- Zhao Yan G.
- Zhao Ying
- Zhao Yongchao
- Zhao Yu-Xia
- Zhao Zhendong
- Zhao Zhizhuang J.
- Zheng Dexian
- Zheng Xi-Long
- Zheng Xiaoxiang
- Zhivotovsky Boris
- Zhong Qing
- Zhou Guang-Zhou
- Zhou Guofei
- Zhou Huiping
- Zhou Shu-Feng
- Zhou Xu-Jie
- Zhu Hongxin
- Zhu Hua
- Zhu Wei-Guo
- Zhu Wenhua
- Zhu Xiao-Feng
- Zhu Yuhua
- Zhuang Shi-Mei
- Zhuang Xiaohong
- Ziparo Elio
- Zois Christos E.
- Zoladek Teresa
- Zong Wei-Xing
- Zorzano Antonio
- Zughaier Susu M.
- Publication venue
- Publication date
- 01/01/2016
- Field of study
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