EL CONTROL SIMULTÁNEO Y LA PREVENCIÓN DE LA CORRUPCIÓN EN LAS CONTRATACIONES DE LAS ENTIDADES PÚBLICAS, EN LA CONTRALORÍA REGIONAL HUÁNUCO - 2017

La presente investigación tiene por objetivo medir la relación del control simultáneo en la prevención de la corrupción en las contrataciones de las entidades públicas, en la Contraloría Regional Huánuco - 2017, esta investigación es de tipo aplicada, de enfoque cuantitativo, de alcance descriptivo correlacional y basado en el método deductivo; donde la variable independiente es el control simultáneo, y la variable dependiente es la prevención de la corrupción en las contrataciones de las entidades públicas. La población está conformada por los trabajadores de la Contraloría Regional Huánuco, los mismos que están directamente involucrados con el problema a investigar y suman en total 34 trabajadores y la muestra será la misma población (N = n). Para la contrastación de la hipótesis se utilizó el programa SPSS versión 22, con la prueba de SPEARMAN y se obtuvo como resultado que la correlación es baja, siendo un 0.297 y el valor de significancia es 0.125, en tal sentido se rechaza la Hipótesis alternativa (Hi) y se acepta la hipótesis nula (Ho); y podemos decir que el control simultáneo no se relaciona significativamente en la prevención de la corrupción en las contrataciones de las entidades públicas, en la Contraloría Regional Huánuco, con una correlación baja de un 30% con un nivel de confianza del 95%.Tesi

Rectovaginal Colonization with Serotypes of Group B Streptococci with Reduced Penicillin Susceptibility among Pregnant Women in Leon, Nicaragua

Group B Streptococci (GBS) are important causes of neonatal sepsis and meningitis globally. To elucidate the potential benefits of maternal GBS vaccines, data is needed on the epidemiology of maternal GBS rectovaginal colonization, distribution of serotypes, and resistance to intrapartum antibiotic prophylaxis (IAP). We collected rectal and vaginal samples from 305 pregnant women in León, Nicaragua between 35 and 40 weeks gestation. Samples were cultured for GBS and confirmed using latex agglutination. GBS isolates underwent serotyping by quantitative polymerase chain reaction, and antimicrobial susceptibility testing by disk diffusion and microdilution following Clinical Laboratory Standard Institute guidelines. Sixty-three women (20.7%) were colonized with GBS in either the rectum or the vagina. Of 91 GBS isolates collected from positive cultures, most were serotypes II (28.6%), Ia (27.5%), and III (20.9%). Most GBS isolates (52.9%) were resistant to penicillin, the first-line prophylactic antibiotic. Penicillin resistance was highly correlated with resistance to vancomycin, ceftriaxone, and meropenem. The results of our study suggest that one-fifth of pregnant women in the urban area of León, Nicaragua are colonized with GBS and risk transmitting GBS to their offspring during labor. High resistance to commonly available antibiotics in the region suggests that prophylactic maternal GBS vaccination would be an effective alternative to IAP

Rectovaginal Colonization with Serotypes of Group B Streptococci with Reduced Penicillin Susceptibility among Pregnant Women in León, Nicaragua

Group B Streptococci (GBS) are important causes of neonatal sepsis and meningitis globally. To elucidate the potential benefits of maternal GBS vaccines, data is needed on the epidemiology of maternal GBS rectovaginal colonization, distribution of serotypes, and resistance to intrapartum antibiotic prophylaxis (IAP). We collected rectal and vaginal samples from 305 pregnant women in León, Nicaragua between 35 and 40 weeks gestation. Samples were cultured for GBS and confirmed using latex agglutination. GBS isolates underwent serotyping by quantitative polymerase chain reaction, and antimicrobial susceptibility testing by disk diffusion and microdilution following Clinical Laboratory Standard Institute guidelines. Sixty-three women (20.7%) were colonized with GBS in either the rectum or the vagina. Of 91 GBS isolates collected from positive cultures, most were serotypes II (28.6%), Ia (27.5%), and III (20.9%). Most GBS isolates (52.9%) were resistant to penicillin, the first-line prophylactic antibiotic. Penicillin resistance was highly correlated with resistance to vancomycin, ceftriaxone, and meropenem. The results of our study suggest that one-fifth of pregnant women in the urban area of León, Nicaragua are colonized with GBS and risk transmitting GBS to their offspring during labor. High resistance to commonly available antibiotics in the region suggests that prophylactic maternal GBS vaccination would be an effective alternative to IAP