Interdisciplinaridade, colaboração e imersão: o design de uma experiência em realidade virtual com o objetivo de preservação da memória

The digital culture has enabled new ways of artifacts fruition in museums. This article addresses the importance of interdisciplinary and collaborative work in the design of projects that use digital technologies to create meaningful experiences for the public. As a case study, it presents the V-Horus project, which has as its objective the digital reconstruction of archaeological artifacts and their visualization through virtual reality. In an experimental phase, the project digitally reconstructed a mummy, from the Egyptian collection of the National Museum of Rio de Janeiro, which was destroyed in the fire that occurred in 2018. In the article, a report is presented of both, the development of the experience and its evaluation by the public, assessed through a survey conducted with 153 users. The results show that the experiment expanded the visualization possibilities of museum collections and that the interdisciplinary approach of the project was essential to create an experience that sensitized and engaged the public.A cultura digital tem possibilitado novas formas de fruição de artefatos em museus. Este artigo aborda a importância do trabalho interdisciplinar e colaborativo no design de projetos que utilizam tecnologias digitais para criar experiências significativas para o público. Como estudo de caso, apresenta o projeto V-Horus, cujo objetivo é a reconstrução digital de artefatos arqueológicos e a sua visualização por meio de realidade virtual. Em fase experimental, o projeto reconstruiu digitalmente uma múmia da coleção egípcia do Museu Nacional do Rio de Janeiro, destruída no incêndio ocorrido em 2018. No artigo, são relatados o desenvolvimento da experiência e a avaliação da mesma pelo público, realizada por meio de uma pesquisa com 153 usuários. Os resultados mostram que o experimento ampliou as possibilidades de visualização dos acervos em museus e que a abordagem interdisciplinar do projeto foi essencial para criar uma experiência que sensibilizasse e engajasse o público

De associatie tussen HTR2C-polymorfismen en de prevalentie van het metabool syndroom bij patiënten die antipsychotica gebruiken: Een replicatiestudie

OBJECTIVE: In two previous studies we found an association between HTR2C polymorphisms and the prevalence of the metabolic syndrome in patients using antipsychotics. In this study, we set out to replicate our findings in a third separate sample of patients. DESIGN AND METHODS: Data for this cross-sectional study came from the ongoing Pharmacotherapy Monitoring and Outcome survey study, investigating the association between schizophrenia and metabolic or cardiovascular risk factors. Primary end point was the prevalence of the metabolic syndrome. Primary determinants were two polymorphisms in the HTR2C gene: rs3813929 (759 C/T) and rs1414334:C>G. RESULTS: Carriership of the variant rs1414334 C allele was significantly associated with an increased prevalence of the metabolic syndrome (odds ratio 3.73; 95% confidence interval 1.29-10.79; P = 0.015). No association was found between the HTR2C 759 C/T polymorphism and the metabolic syndrome. CONCLUSION: This study confirms previous findings that the variant C-allele of the rs1414334 polymorphism is associated with the metabolic syndrome

Association between HTR2C gene polymorphisms and the metabolic syndrome in patients using antipsychotics: A replication study

OBJECTIVE: In two previous studies we found an association between HTR2C polymorphisms and the prevalence of the metabolic syndrome in patients using antipsychotics. In this study, we set out to replicate our findings in a third separate sample of patients. DESIGN AND METHODS: Data for this cross-sectional study came from the ongoing Pharmacotherapy Monitoring and Outcome survey study, investigating the association between schizophrenia and metabolic or cardiovascular risk factors. Primary end point was the prevalence of the metabolic syndrome. Primary determinants were two polymorphisms in the HTR2C gene: rs3813929 (759 C/T) and rs1414334:C>G. RESULTS: Carriership of the variant rs1414334 C allele was significantly associated with an increased prevalence of the metabolic syndrome (odds ratio 3.73; 95% confidence interval 1.29-10.79; P = 0.015). No association was found between the HTR2C 759 C/T polymorphism and the metabolic syndrome. CONCLUSION: This study confirms previous findings that the variant C-allele of the rs1414334 polymorphism is associated with the metabolic syndrome