10 research outputs found
Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity.
- Author
- Aanensen David M
- Abudahab Khalil
- Acheson Erwan
- Adams Alexander
- Adams Helen
- Adriaenssens Evelien M
- Afifi Safiah
- Aggarwal Dinesh
- Ahmad Shazaad SY
- Alam Mohammad T
- Alcolea-Medina Adela
- Alderton Alex
- Alikhan Nabil-Fareed
- Allan John
- Allara Elias
- Amato Roberto
- Andersson Monique
- Angyal Adrienn
- Aranday-Cortes Elihu
- Ariani Cristina
- Asad Hibo
- Asamaphan Patawee
- Ashworth Jordan
- Atkinson Laura
- Attwood Stephen
- Auckland Cressida
- Awan Ali R
- Aydin Alp
- Baker David J
- Baker Paul
- Balcazar Carlos E
- Ball Jonathan
- Barton Edward
- Bashton Matthew
- Batra Rahul
- Baxter Laura
- Beale Mathew A
- Beaver Charlotte
- Beckett Angela
- Beer Robert
- Beggs Andrew
- Bell Andrew
- Bellis Katherine L
- Berger Duncan J
- Berriman Matt
- Berry Lisa
- Berry Louise
- Betancor Gilberto
- Betteridge Emma
- Bewshea Claire M
- Bibby David
- Bicknell Kelly
- Birchley Alec
- Bird Paul
- Bishop Chloe
- Blane Beth
- Bolt Frances
- Bonsall David
- Boswell Tim
- Bosworth Andrew
- Bourgeois Yann
- Boyd Olivia
- Boyes John
- Bradley Declan T
- Bradshaw Daniel
- Breen Cassie
- Bresner Catherine
- Breuer Judith
- Bridgewater Hannah E
- Brooks Tony T
- Broos Alice
- Brown Julianne Rose
- Brown Paul E
- Brown Rebecca
- Brunker Kirstyn
- Bucca Giselda
- Buck David
- Buddenborg Sarah K
- Bull Matthew
- Bull Matthew
- Burton-Fanning Shirelle
- Butcher Ethan
- Caddy Sarah L
- Caller Laura G
- Campbell Sharon
- Carlile Matthew
- Carmichael Stephen N
- Casey Anna
- Castellano Sergi
- Chalker Vicki
- Chand Meera
- Chapman Michael R
- Chappell Joseph G
- Charalampous Themoula
- Charles Ian G
- Chaudhry Yasmin
- Chauhan Anoop J
- Cheng Jeffrey KJ
- Churcher Carol M
- Clark Gemma
- Coll Francesc
- Collins Jennifer
- Colquhoun Rachel
- Colquhoun Rachel M
- Connor Thomas R
- Connor Thomas R
- Constantinidou Chrystala
- Coombes Jason
- Corden Sally
- Cormie Claire
- Cortes Nicholas
- Cortes Nick
- Cottrell Simon
- Coupland Lindsay J
- Cowell Angela
- Cox Alison
- Craine Noel
- Cronin Michelle
- Crooke Derrick
- Curran Martin D
- Curran Tanya
- da Silva Filipe Ana
- da Silva Filipe Ana
- Dabrera Gavin
- Danesh John
- Darby Alistair C
- Davidson Rose K
- Davies Alisha
- Davis Thomas
- de Cesare Mariateresa
- De Lacy Elen
- de Oliveira Martins Leonardo
- de Silva Thushan I
- Debebe Johnny
- Dervisevic Samir
- Dewar Rebecca
- Dias Joana
- Diaz Maria
- Dibling Thomas
- Dorman Matthew J
- Downing Fatima
- Drury Eleanor
- du Plessis Louis
- Duckworth Nichola
- Dyal Patricia L
- Eccles Richard
- Edgeworth Jonathan
- Edwards Sue
- Eldirdiri Sahar
- Ellaby Nicholas
- Ellard Sian
- Elliott Scott
- Eltringham Gary
- Elumogo Ngozi
- Essex Sarah
- Evans Cariad
- Evans Johnathan M
- Eyre David
- Fairley Derek J
- Fallon Karlie
- Farbos Audrey
- Farr Ben
- Feltwell Theresa
- Fina Laia
- Findlay Jacqueline
- Fisher Chloe L
- Fleming Vicki M
- Forrest Leysa M
- Forrest Sally
- Foulser Luke
- Francois Sarah
- Fraser Christophe
- Freeman Timothy M
- Frost Lucy R
- Fuller William
- Gallagher Eileen
- Gallagher Michael D
- Garcia-Casado Maria V
- Gaskin Amy
- Gatica-Wilcox Bree
- Gavriil Artemis
- Geidelberg Lily
- Geidelberg Lily
- Gemmell Matthew
- Georgana Iliana
- George Ryan P
- Gifford Laura
- Gilbert Lauren
- Gill Harmeet K
- Gilroy Rachel AJ
- Girgis Sophia T
- Glaysher Sharon
- Golubchik Tanya
- Goncalves Sonia
- Goodfellow Ian
- Goodfellow Ian G
- Goodwin Scott
- Graham Clive
- Graham Lee
- Grammatopoulos Dimitris
- Green Angie
- Green Luke R
- Greenaway Jane
- Gregory Richard
- Griffith Luke
- Groves Danielle C
- Groves Natalie
- Guest Martyn
- Gulliver Huw
- Gutierrez Ana Victoria
- Hadjirin Nazreen F
- Haldenby Sam T
- Hale Antony D
- Hall Grant
- Halstead Fenella
- Hamilton William L
- Haque Tanzina
- Harper Katherine L
- Harris Kathryn Ann
- Harrison Ewan M
- Harrison Ian
- Harrison James W
- Hartman Hassan
- Hattersley Andrew
- Heaney Judith
- Helmer Thomas
- Hesketh Andrew R
- Heyburn David
- Higginson Ellen E
- Hill Verity
- Hill Verity
- Hilvers Ember
- Hiscox Julian A
- Holden Matthew TG
- Holmes Alison
- Holmes Christopher
- Holmes Nadine
- Hoosdally Sarah
- Hopes Richard
- Hosmillo Myra
- Houldcroft Charlotte J
- Howe Robin
- Howson-Wells Hannah C
- Hubb Jonathan
- Hughes Joseph
- Hughes Margaret
- Hunter Adam D
- Hutchings Stephanie
- Impey Robert
- Irish-Tavares Dianne
- Iturriza-Gomara Miren
- Jackson Ben
- Jackson Ben
- Jackson David A
- Jackson David K
- Jackson Kathryn A
- Jahun Aminu S
- James Keith
- Jamrozy Dorota
- Jarrett Ruth
- Jeffries Aaron R
- Jesudason Natasha
- Jesudason Natasha G
- John Michaela
- Johnson Kate
- Johnson Natasha
- Johnson Rob
- Johnson Robert
- Johnston Ian
- Jones Hannah
- Jones Katie
- Jones Rachel
- Jones Sophie
- Jorgensen David
- Jorgensen David
- Joseph Amelia
- Justice Anita
- Kane Leanne
- Kay Gemma L
- Kay Sally
- Keatley Jon-Paul
- Keeley Alexander J
- Kenyon Anita
- Kermack Leanne M
- Khakh Manjinder
- Khokhar Fahad A
- Kidd Stephen
- Kingsley Robert A
- Kitchen Christine
- Knight Bridget A
- Kolyva Anastasia
- Koshy Cherian
- Kraemer Moritz
- Kristiansen Mark
- Kumziene-Summerhayes Sara
- Kwiatkowski Dominic
- Lackenby Angie
- Langford Cordelia
- Lawniczak Mara
- Le-Viet Thanh
- Lee David
- Lee Jack CD
- Letchford Laura
- Levene Nick
- Levett Lisa J
- Li Kathy
- Li Kathy K
- Liggett Steven
- Lindsey Benjamin B
- Lister Michelle M
- Livett Rich
- Lloyd Allyson
- Lo Stephanie
- Loh Joshua
- Loman Nicholas J
- Loman Nicholas J
- Loose Matthew W
- Loveson Katie F
- Lowe Hannah
- Lucaci Anita O
- Ludden Catherine
- Lynch Jessica
- Lyons Ronan A
- Macfarlane-Smith Louissa R
- Machin Nicholas W
- MacIntyre-Cockett George
- Madona Pinglawathee
- Maes Mailis
- Mahungu Tabitha W
- Mair Daniel
- Maksimovic Joshua
- Manesis Nikos
- Manley Robin
- Manso Carmen
- Marchbank Angela
- Martincorena Inigo
- Martinez-Nunez Rocio T
- Masoli Jane AH
- Mason Jenifer
- Mather Alison E
- Mbisa Tamyo
- McCluggage Kathryn
- McClure Patrick C
- McCrone John T
- McCrone JT
- McGuigan Samantha
- McHugh Martin P
- McKenna James P
- McKerr Caoimhe
- McMinn Liz
- McMurray Claire
- Meader Emma J
- Meadows Lizzie
- Menegazzo Mirko
- Meredith Luke W
- Merrick Ian
- Mestek-Boukhibar Lamia
- Miah Shahjahan
- Michell Stephen L
- Michelsen Michelle L
- Molnar Zoltan
- Monaghan Lynn
- Mookerjee Siddharth
- Moore Catherine
- Moore Catrin
- Moore Christopher
- Moore Nathan
- Morgan Mari
- Morgan Sian
- Mori Matilde
- Moses Samuel
- Muir Peter
- Munn Robert
- Myers Richard
- Nascimento Fabricia F
- Nascimento Fabricia F
- Naydenova Plamena
- Neaverson Alexandra S
- Nebbia Gaia
- Nelson Andrew
- Nelson Charlotte
- Nelson Rachel
- Nicholls Sam
- Nicholls Samuel M
- Nichols Jenna
- Niebel Marc O
- Niola Paola
- Nomikou Kyriaki
- O'Toole Elaine
- O'Toole Áine
- Orton Richard J
- Osman Husam
- Ott Sascha
- O’Grady Justin
- O’Toole Áine
- Pacchiarini Nicole
- Pacchiarini Nicole
- Padgett Debra
- Page Andrew J
- Palmer Sophie
- Palmer Steve
- Panchbhaya Yasmin N
- Pandey Sarojini
- Park Naomi
- Parker Matthew D
- Parmar Surendra
- Parr Yasmin A
- Parsons Paul J
- Partridge David G
- Pascall David J
- Patel Gaurang
- Patel Minal
- Patel Vineet
- Paterson Steve
- Payne Brendan AI
- Peacock Sharon J
- Pearson Clare
- Perry Malorie
- Peto Timothy
- Pinckert Malte L
- Platt Steven
- Plimmer Amy
- Poplawski Radoslaw
- Potter Will
- Prakash Reenesh
- Prestwood Liam
- Price Anna
- Price Anna
- Price James
- Puethe Christoph
- Pybus Oliver
- Pybus Oliver G
- Pymont Hannah M
- Quail Mike
- Quick Joshua
- Raghwani Jayna
- Ragonnet-Cronin Manon
- Rainbow Lucille
- Rajatileka Shavanthi
- Rambaut Andrew
- Rambaut Andrew
- Ramsay Mary
- Randell Paul A
- Raviprakash Veena
- Raza Mohammad
- Resende Silva Paola C
- Rey Sara
- Rey Sara M
- Reynolds Nicola
- Richter Alex
- Robertson David L
- Robertson David L
- Robinson Esther
- Robinson Trevor I
- Robson Samuel C
- Rogers Hazel A
- Rooke Stefan
- Rowan Aileen
- Rowe Will
- Roy Sunando
- Rudder Steven
- Ruis Chris
- Ryan Felicity
- Sambles Christine M
- Sang Fei
- Scarlett Garry P
- Schaefer Ulf
- Scher Emily
- Scott Carol
- Scott Garren
- Sethi Dheeraj K
- Shaaban Sharif
- Shah Divya
- Shah Rajiv
- Shah Rajiv N
- Shankar Giri
- Shaw Robert
- Shepherd James
- Shepherd James G
- Sheriff Nicola
- Shirley Lesley
- Signell Adrian W
- Sillitoe John
- Simpson David A
- Singer Joshua B
- Sivaprakasam Venkat
- Siveroni Igor
- Siveroni Igor
- Sloan Tim J
- Sluga Graciela
- Smith Christen
- Smith Colin P
- Smith Darren L
- Smith Nikki
- Smith Wendy
- Smollett Katherine L
- Snell Luke B
- Souster Emily
- Southgate Joel
- Southgate Joel
- Spellman Karla
- Spencer-Chapman Michael
- Sridhar Sushmita
- Stanley Rachael
- Stanton Thomas D
- Starinskij Igor
- Stark Richard
- Stockton Joanne
- Stuart Claire
- Studholme David J
- Swindells Emma
- Swingler Tracey
- Taha Yusri
- Tang Julian
- Taylor Ben EW
- Taylor Graham P
- Taylor Sarah
- Taylor-Joyce Grace
- Tedim Ana P
- Temperton Ben
- Templeton Kate E
- Thompson Thomas
- Thomson Emma C
- Thomson Emma C
- Thomson Nicholas M
- Thornton Alicia
- Thurston Scott
- Todd John A
- Tong Lily
- Tonkin-Hill Gerry
- Torok M Estee
- Trebes Amy
- Trotter Alexander J
- Tsoleridis Theocharis
- Tucker Rachel M
- Turtle Lance
- Tutill Helena J
- Underwood Anthony P
- Unnikrishnan Meera
- Vamos Edith E
- Vasylyeva Tetyana
- Vattipally Sreenu
- Vipond Ian B
- Volz Erik
- Volz Erik M
- Wain John
- Walsh Sarah
- Wang Dennis
- Wantoch Michelle
- Warne Ben
- Warwick-Dugdale Joanna
- Wastenge Elizabeth
- Watkins Joanne
- Watts Joanne
- Waugh Sheila
- Webber Mark A
- Weeks Sam
- Weldon Danni
- Whitehead Mark
- Williams Charlotte A
- Williams Chris
- Williams David
- Williams Rachel J
- Williams Rebecca
- Williams Thomas
- Williamson Kathleen A
- Willingham Iona
- Wilson Harry D
- Wise Emma
- Workman Trudy
- Wright Victoria
- Wyles Matthew
- Wyllie Sarah
- Yakovleva Anna
- Yasir Muhammad
- Yeats Corin A
- Yew Wen C
- Young Gregory R
- Young Jamie
- Yu Xiaoyu
- Zarebski Alex
- Publication venue
- Cell
- Publication date
- 01/09/2020
- Field of study
Global dispersal and increasing frequency of the SARS-CoV-2 spike protein variant D614G are suggestive of a selective advantage but may also be due to a random founder effect. We investigate the hypothesis for positive selection of spike D614G in the United Kingdom using more than 25,000 whole genome SARS-CoV-2 sequences. Despite the availability of a large dataset, well represented by both spike 614 variants, not all approaches showed a conclusive signal of positive selection. Population genetic analysis indicates that 614G increases in frequency relative to 614D in a manner consistent with a selective advantage. We do not find any indication that patients infected with the spike 614G variant have higher COVID-19 mortality or clinical severity, but 614G is associated with higher viral load and younger age of patients. Significant differences in growth and size of 614G phylogenetic clusters indicate a need for continued study of this variant
Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity
- Author
- Aanensen David M.
- Abudahab Khalil
- Acheson Erwan
- Adams Alexander
- Adams Helen
- Adriaenssens Evelien M.
- Afifi Safiah
- Aggarwal Dinesh
- Ahmad Shazaad S.Y.
- Alam Mohammad T.
- Alcolea-Medina Adela
- Alderton Alex
- Alikhan Nabil-Fareed
- Allan John
- Allara Elias
- Amato Roberto
- Andersson Monique
- Angyal Adrienn
- Aranday-Cortes Elihu
- Ariani Cristina
- Asad Hibo
- Asamaphan Patawee
- Ashworth Jordan
- Atkinson Laura
- Attwood Stephen
- Auckland Cressida
- Awan Ali R.
- Aydin Alp
- Baker David J.
- Baker Paul
- Balcazar Carlos E.
- Ball Jonathan
- Barton Edward
- Bashton Matthew
- Batra Rahul
- Baxter Laura
- Beale Mathew A.
- Beaver Charlotte
- Beckett Angela
- Beer Robert
- Beggs Andrew
- Bell Andrew
- Bellis Katherine L.
- Berger Duncan J.
- Berriman Matt
- Berry Lisa
- Berry Louise
- Betancor Gilberto
- Betteridge Emma
- Bewshea Claire M.
- Bibby David
- Bicknell Kelly
- Birchley Alec
- Bird Paul
- Bishop Chloe
- Blane Beth
- Bolt Frances
- Bonsall David
- Boswell Tim
- Bosworth Andrew
- Bourgeois Yann
- Boyd Olivia
- Boyes John
- Bradley Declan T.
- Bradshaw Daniel
- Breen Cassie
- Bresner Catherine
- Breuer Judith
- Bridgewater Hannah E.
- Brooks Tony T.
- Broos Alice
- Brown Julianne Rose
- Brown Paul E.
- Brown Rebecca
- Brunker Kirstyn
- Bucca Giselda
- Buck David
- Buddenborg Sarah K.
- Bull Matthew
- Bull Matthew
- Burton-Fanning Shirelle
- Butcher Ethan
- Caddy Sarah L.
- Caller Laura G.
- Campbell Sharon
- Carlile Matthew
- Carmichael Stephen N.
- Casey Anna
- Castellano Sergi
- Chalker Vicki
- Chand Meera
- Chapman Michael R.
- Chappell Joseph G.
- Charalampous Themoula
- Charles Ian G.
- Chaudhry Yasmin
- Chauhan Anoop J.
- Cheng Jeffrey K.J.
- Churcher Carol M.
- Clark Gemma
- Coll Francesc
- Collins Jennifer
- Colquhoun Rachel
- Colquhoun Rachel M.
- Connor Thomas R.
- Connor Thomas R.
- Constantinidou Chrystala
- Coombes Jason
- Corden Sally
- Cormie Claire
- Cortes Nicholas
- Cortes Nick
- Cottrell Simon
- Coupland Lindsay J.
- Cowell Angela
- Cox Alison
- Craine Noel
- Cronin Michelle
- Crooke Derrick
- Curran Martin D.
- Curran Tanya
- da Silva Filipe Ana
- da Silva Filipe Ana
- Dabrera Gavin
- Danesh John
- Darby Alistair C.
- Davidson Rose K.
- Davies Alisha
- Davis Thomas
- de Cesare Mariateresa
- De Lacy Elen
- de Oliveira Martins Leonardo
- de Silva Thushan I.
- Debebe Johnny
- Dervisevic Samir
- Dewar Rebecca
- Dias Joana
- Diaz Maria
- Dibling Thomas
- Dorman Matthew J.
- Downing Fatima
- Drury Eleanor
- du Plessis Louis
- Duckworth Nichola
- Dyal Patricia L.
- Eccles Richard
- Edgeworth Jonathan
- Edwards Sue
- Eldirdiri Sahar
- Ellaby Nicholas
- Ellard Sian
- Elliott Scott
- Eltringham Gary
- Elumogo Ngozi
- Essex Sarah
- Evans Cariad
- Evans Johnathan M.
- Eyre David
- Fairley Derek J.
- Fallon Karlie
- Farbos Audrey
- Farr Ben
- Feltwell Theresa
- Fina Laia
- Findlay Jacqueline
- Fisher Chloe L.
- Fleming Vicki M.
- Forrest Leysa M.
- Forrest Sally
- Foulser Luke
- Francois Sarah
- Fraser Christophe
- Freeman Timothy M.
- Frost Lucy R.
- Fuller William
- Gallagher Eileen
- Gallagher Michael D.
- Garcia-Casado Maria V.
- Gaskin Amy
- Gatica-Wilcox Bree
- Gavriil Artemis
- Geidelberg Lily
- Geidelberg Lily
- Gemmell Matthew
- Georgana Iliana
- George Ryan P.
- Gifford Laura
- Gilbert Lauren
- Gill Harmeet K.
- Gilroy Rachel A.J.
- Girgis Sophia T.
- Glaysher Sharon
- Golubchik Tanya
- Goncalves Sonia
- Goodfellow Ian
- Goodfellow Ian G.
- Goodwin Scott
- Graham Clive
- Graham Lee
- Gramatopoulos Dimitris
- Green Angie
- Green Luke R.
- Greenaway Jane
- Gregory Richard
- Griffith Luke
- Groves Danielle C.
- Groves Natalie
- Guest Martyn
- Gulliver Huw
- Gutierrez Ana Victoria
- Hadjirin Nazreen F.
- Haldenby Sam T.
- Hale Antony D.
- Hall Grant
- Halstead Fenella
- Hamilton William L.
- Haque Tanzina
- Harper Katherine L.
- Harris Kathryn Ann
- Harrison Ewan M.
- Harrison Ian
- Harrison James W.
- Hartman Hassan
- Hattersley Andrew
- Heaney Judith
- Helmer Thomas
- Hesketh Andrew R.
- Heyburn David
- Higginson Ellen E.
- Hill Verity
- Hill Verity
- Hilvers Ember
- Hiscox Julian A.
- Holden Matthew T.G.
- Holmes Alison
- Holmes Christopher
- Holmes Nadine
- Hoosdally Sarah
- Hopes Richard
- Hosmillo Myra
- Houldcroft Charlotte J.
- Howe Robin
- Howson-Wells Hannah C.
- Hubb Jonathan
- Hughes Joseph
- Hughes Margaret
- Hunter Adam D.
- Hutchings Stephanie
- Impey Robert
- Irish-Tavares Dianne
- Iturriza-Gomara Miren
- Jackson Ben
- Jackson Ben
- Jackson David A.
- Jackson David K.
- Jackson Kathryn A.
- Jahun Aminu S.
- James Keith
- Jamrozy Dorota
- Jarrett Ruth
- Jeffries Aaron R.
- Jesudason Natasha
- Jesudason Natasha G.
- John Michaela
- Johnson Kate
- Johnson Natasha
- Johnson Rob
- Johnson Robert
- Johnston Ian
- Jones Hannah
- Jones Katie
- Jones Rachel
- Jones Sophie
- Jorgensen David
- Jorgensen David
- Joseph Amelia
- Justice Anita
- Kane Leanne
- Kay Gemma L.
- Kay Sally
- Keatley Jon-Paul
- Keeley Alexander J.
- Kenyon Anita
- Kermack Leanne M.
- Khakh Manjinder
- Khokhar Fahad A.
- Kidd Stephen
- Kingsley Robert A.
- Kitchen Christine
- Knight Bridget A.
- Kolyva Anastasia
- Koshy Cherian
- Kraemer Moritz
- Kristiansen Mark
- Kumziene-Summerhayes Sara
- Kwiatkowski Dominic
- Lackenby Angie
- Langford Cordelia
- Lawniczak Mara
- Le-Viet Thanh
- Lee David
- Lee Jack C.D.
- Letchford Laura
- Levene Nick
- Levett Lisa J.
- Li Kathy
- Li Kathy K.
- Liggett Steven
- Lindsey Benjamin B.
- Lister Michelle M.
- Livett Rich
- Lloyd Allyson
- Lo Stephanie
- Loh Joshua
- Loman Nicholas J.
- Loman Nicholas J.
- Loose Matthew W.
- Loveson Katie F.
- Lowe Hannah
- Lucaci Anita O.
- Ludden Catherine
- Lynch Jessica
- Lyons Ronan A.
- Macfarlane-Smith Louissa R.
- Machin Nicholas W.
- MacIntyre-Cockett George
- Madona Pinglawathee
- Maes Mailis
- Mahungu Tabitha W.
- Mair Daniel
- Maksimovic Joshua
- Manesis Nikos
- Manley Robin
- Manso Carmen
- Marchbank Angela
- Martincorena Inigo
- Martinez-Nunez Rocio T.
- Masoli Jane A.H.
- Mason Jenifer
- Mather Alison E.
- Mbisa Tamyo
- McCluggage Kathryn
- McClure Patrick C.
- McCrone J.T.
- McCrone John T.
- McGuigan Samantha
- McHugh Martin P.
- McKenna James P.
- McKerr Caoimhe
- McMinn Liz
- McMurray Claire
- Meader Emma J.
- Meadows Lizzie
- Menegazzo Mirko
- Meredith Luke W.
- Merrick Ian
- Mestek-Boukhibar Lamia
- Miah Shahjahan
- Michell Stephen L.
- Michelsen Michelle L.
- Molnar Zoltan
- Monaghan Lynn
- Mookerjee Siddharth
- Moore Catherine
- Moore Catrin
- Moore Christopher
- Moore Nathan
- Morgan Mari
- Morgan Sian
- Mori Matilde
- Moses Samuel
- Muir Peter
- Munn Robert
- Myers Richard
- Nascimento Fabricia F.
- Nascimento Fabricia F.
- Naydenova Plamena
- Neaverson Alexandra S.
- Nebbia Gaia
- Nelson Andrew
- Nelson Charlotte
- Nelson Rachel
- Nicholls Sam
- Nicholls Samuel M.
- Nichols Jenna
- Niebel Marc O.
- Niola Paola
- Nomikou Kyriaki
- O'Toole Elaine
- O'Toole Áine
- Orton Richard J.
- Osman Husam
- Ott Sascha
- O’Grady Justin
- O’Toole Áine
- Pacchiarini Nicole
- Pacchiarini Nicole
- Padgett Debra
- Page Andrew J.
- Palmer Sophie
- Palmer Steve
- Panchbhaya Yasmin N.
- Pandey Sarojini
- Park Naomi
- Parker Matthew D.
- Parmar Surendra
- Parr Yasmin A.
- Parsons Paul J.
- Partridge David G.
- Pascall David J.
- Patel Gaurang
- Patel Minal
- Patel Vineet
- Paterson Steve
- Payne Brendan A.I.
- Peacock Sharon J.
- Pearson Clare
- Perry Malorie
- Peto Timothy
- Pinckert Malte L.
- Platt Steven
- Plimmer Amy
- Poplawski Radoslaw
- Potter Will
- Prakash Reenesh
- Prestwood Liam
- Price Anna
- Price Anna
- Price James
- Puethe Christoph
- Pybus Oliver
- Pybus Oliver G.
- Pymont Hannah M.
- Quail Mike
- Quick Joshua
- Raghwani Jayna
- Ragonnet-Cronin Manon
- Rainbow Lucille
- Rajatileka Shavanthi
- Rambaut Andrew
- Rambaut Andrew
- Ramsay Mary
- Randell Paul A.
- Raviprakash Veena
- Raza Mohammad
- Resende Silva Paola C.
- Rey Sara
- Rey Sara M.
- Reynolds Nicola
- Richter Alex
- Robertson David L.
- Robertson David L.
- Robinson Esther
- Robinson Trevor I.
- Robson Samuel C.
- Rogers Hazel A.
- Rooke Stefan
- Rowan Aileen
- Rowe Will
- Roy Sunando
- Rudder Steven
- Ruis Chris
- Ryan Felicity
- Sambles Christine M.
- Sang Fei
- Scarlett Garry P.
- Schaefer Ulf
- Scher Emily
- Scott Carol
- Scott Garren
- Sethi Dheeraj K.
- Shaaban Sharif
- Shah Divya
- Shah Rajiv
- Shah Rajiv N.
- Shankar Giri
- Shaw Robert
- Shepherd James
- Shepherd James G.
- Sheriff Nicola
- Shirley Lesley
- Signell Adrian W.
- Sillitoe John
- Simpson David A.
- Singer Joshua B.
- Sivaprakasam Venkat
- Siveroni Igor
- Siveroni Igor
- Sloan Tim J.
- Sluga Graciela
- Smith Christen
- Smith Colin P.
- Smith Darren
- Smith Nikki
- Smith Wendy
- Smollett Katherine L.
- Snell Luke B.
- Souster Emily
- Southgate Joel
- Southgate Joel
- Spellman Karla
- Spencer-Chapman Michael
- Sridhar Sushmita
- Stanley Rachael
- Stanton Thomas D.
- Starinskij Igor
- Stark Richard
- Stockton Joanne
- Stuart Claire
- Studholme David J.
- Swindells Emma
- Swingler Tracey
- Taha Yusri
- Tang Julian
- Taylor Ben E.W.
- Taylor Graham P.
- Taylor Sarah
- Taylor-Joyce Grace
- Tedim Ana P.
- Temperton Ben
- Templeton Kate E.
- Thompson Thomas
- Thomson Emma C.
- Thomson Emma C.
- Thomson Nicholas M.
- Thornton Alicia
- Thurston Scott
- Todd John A.
- Tong Lily
- Tonkin-Hill Gerry
- Torok M. Estee
- Trebes Amy
- Trotter Alexander J.
- Tsoleridis Theocharis
- Tucker Rachel M.
- Turtle Lance
- Tutill Helena J.
- Underwood Anthony P.
- Unnikrishnan Meera
- Vamos Edith E.
- Vasylyeva Tetyana
- Vattipally Sreenu
- Vipond Ian B.
- Volz Erik
- Volz Erik M.
- Wain John
- Walsh Sarah
- Wang Dennis
- Wantoch Michelle
- Warne Ben
- Warwick-Dugdale Joanna
- Wastenge Elizabeth
- Watkins Joanne
- Watts Joanne
- Waugh Sheila
- Webber Mark A.
- Weeks Sam
- Weldon Danni
- Whitehead Mark
- Williams Charlotte A.
- Williams Chris
- Williams David
- Williams Rachel J.
- Williams Rebecca
- Williams Thomas
- Williamson Kathleen A.
- Willingham Iona
- Wilson Harry D.
- Wise Emma
- Workman Trudy
- Wright Victoria
- Wyles Matthew
- Wyllie Sarah
- Yakovleva Anna
- Yasir Muhammad
- Yeats Corin A.
- Yew Wen C.
- Young Gregory R.
- Young Jamie
- Yu Xiaoyu
- Zarebski Alex
- Publication venue
- Elsevier
- Publication date
- 07/01/2021
- Field of study
Global dispersal and increasing frequency of the SARS-CoV-2 spike protein variant D614G are suggestive of a selective advantage but may also be due to a random founder effect. We investigate the hypothesis for positive selection of spike D614G in the United Kingdom using more than 25,000 whole genome SARS-CoV-2 sequences. Despite the availability of a large dataset, well represented by both spike 614 variants, not all approaches showed a conclusive signal of positive selection. Population genetic analysis indicates that 614G increases in frequency relative to 614D in a manner consistent with a selective advantage. We do not find any indication that patients infected with the spike 614G variant have higher COVID-19 mortality or clinical severity, but 614G is associated with higher viral load and younger age of patients. Significant differences in growth and size of 614G phylogenetic clusters indicate a need for continued study of this variant
Institutionalizing a Social Justice Mission for Clinical Legal Education: Cross-National Currents from India and the United States
- Author
- &
- ** Lecturer In Law
- A M Ass&apos
- A M Ass&apos
- A M Ass&apos
- A M Ass&apos
- A M Bar Ass&apos
- A M Bar Ass&apos
- A M Bar Ass&apos
- A M Bar Ass&apos
- A S Anand
- Alan Merson
- Bradway
- Cle And The Lawyer&apos
- Cle And The Lawyer&apos
- D K Sharma
- E G See
- Educating For
- Francis Coralie V
- Francis Coralie V
- G Cooper
- Id
- Id
- India Government Of
- Indian Bar Rev
- John S Bradway
- Justice Jitendra
- M C Mehta V
- M C Mehta V
- M H See
- M H See
- M R K Prasad&apos
- M. R. K. Prasad
- Maureen E Laflin
- Maureen E Laflin
- Michael Norwood
- Michael Norwood
- N L Mitra
- N R Menon
- P Chidambaram
- Peter A Joy
- Peter A Joy
- R Madhav
- Report And
- Report And
- Robert Maccrate
- Robert Maccrate
- Russell Engler
- Russell Engler
- Russell G Pearce
- Russell G Pearce
- S C
- S C
- S Frank
- S Natwarlal
- See Id
- Sheela Barse
- Sheela Barse
- Taylor Von Mehren
- Taylor Von Mehren
- Unni Krishnan V
- Unni Krishnan V
- Veena Sethi V
- Veena Sethi V
- � Frank
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2005
- Field of study
Genome-wide analysis and expression profiles of glyoxalase gene families in Chinese cabbage (Brassica rapa L)
- Author
- A Ghosh
- A Mustafiz
- A Mustafiz
- AY Guo
- B Ali
- B Yang
- Biyun Chen
- C Kaur
- C Kaur
- C Paulus
- C Tong
- C Wu
- F Lin
- FA Shamsi
- Fugui Zhang
- Guixin Yan
- Guizhen Gao
- GX Yan
- HS Nyandieka
- J Chen
- J Espartero
- J Li
- J Li
- Jiangwei Qiao
- K Yamaguchi-Shinozaki
- KJ Livak
- Kun Xu
- LG Együd
- M Jain
- M Lescot
- M Saxena
- M Saxena
- M Skipsey
- M Tuomainen
- M Verma
- MA Hossain
- MA Hossain
- MA Hossain
- Maoteng Li
- MK Maiti
- N Wang
- Nian Wang
- O Emanuelsson
- O Ramaswamy
- P Bhomkar
- P Horton
- PJ Thornalley
- R Deswal
- S Devanathan
- SD Roy
- SJ Norton
- SK Yadav
- SK Yadav
- SK Yadav
- SL Clugston
- SL Singla-Pareek
- SL Singla-Pareek
- SL Singla-Pareek
- T Zimaro
- U Nagaharu
- U Sethi
- V Cardoza
- V Talesa
- Viveros MF Alvarez
- VS Veena Reddy
- W Chen
- W Deng
- X Alvarez-Gerding
- Xiaoming Wu
- Xin Xiao
- XW Wang
- Z Ahmad
- Z Zeng
- ZY Chen
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- Field of study
Differential secretome analysis reveals CST6 as a suppressor of breast cancer bone metastasis
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- A Bialas
- A Jemal
- A Muller
- A Subramanian
- AF Chambers
- AG Rivenbark
- AG Rivenbark
- AJ Minn
- AJ Minn
- B Gyorffy
- CC Wu
- CL Wang
- D Caccia
- D Keppler
- Da Fu
- DT Ross
- E Krepela
- ED Giles
- F Mbeunkui
- F Rondepierre
- G Sotiropoulou
- GR Mundy
- Guohong Hu
- H Xue
- H Xue
- Hui Li
- I Serganova
- J Condeelis
- J Ochieng
- J Zhang
- JD Bendtsen
- JD Bendtsen
- JE Koblinski
- JJ Briggs
- JM Rae
- JM Rae
- KH Chiu
- KJ Yoon
- KR Hess
- L Ai
- L Yao
- L Ye
- L Zhong
- Lei Jin
- Ling Yao
- Lisa X Xu
- LJ Suva
- LM Coussens
- LP Weng
- M Egeblad
- M Gronborg
- M Korpal
- M Ohanna
- M Rocco
- MK Kashyap
- MP Ween
- MR Morris
- MS Veena
- MY Tseng
- N Sethi
- N Vigneswaran
- ND Rawlings
- P Kreunin
- PD Bos
- PL Zeeuwen
- PL Zeeuwen
- RN Kaplan
- RR Langley
- S Sellappan
- SM Pulukuri
- SY Yang
- T Cheng
- T Nomura
- TY Kim
- V Ganapathy
- X Lu
- X Lu
- XH Zhang
- Xiaofang Hu
- Xuebiao Yao
- Y Kang
- Y Shen
- Yan Zhang
- YT Chang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Microbiota in pancreatic health and disease: the next frontier in microbiome research
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- A Bravo-Blas
- A Isaiah
- A Sivan
- A Stenwall
- AB Roberts
- AB Veena
- AD Kostic
- AF Peery
- AG Davis-Richardson
- AK Alkanani
- AL Widdison
- AM Saad
- American Diabetes Association
- B Aykut
- B Routy
- BD Wallace
- BJ Ammori
- C Varol
- CC Patterson
- Christian Jobin
- CJ Doyle
- CJ O’Boyle
- CL Bevins
- CL Sears
- CM Dejea
- CT Brown
- D Adeloye
- D Endesfelder
- D Koziel
- D Yadav
- DS Michaud
- DT Le
- E Del Castillo
- E Marietta
- E Nistal
- E Riquelme
- E Sabbah
- E Zaura
- EA Grice
- EAM Gale
- EB Hollister
- ES Shepherd
- F Bray
- FE Dewhirst
- G Nakatsu
- G Ou
- GB Grindey
- GE Diehl
- GS Cooper
- H Chen
- H Karjula
- H Liu
- H Matthaei
- H Nishiyama
- H Tilg
- HA Burris
- HG Beger
- Human Microbiome Project Consortium.
- J Ahn
- J Li
- J MacFie
- J Ochoa-Repáraz
- J Spicak
- J Sun
- J Tu
- JA Gilbert
- JC Arthur
- JJ Farrell
- JL McQuade
- JR Brahmer
- K Madhani
- K Takeda
- K Uchida
- KB Martinez
- L Rahib
- L Wen
- LK Winer
- LT Geller
- LV Hooper
- M Ahuja
- M Compagno
- M Schmitt
- M Tanaka
- M Vétizou
- M Yamamoto
- MC de Goffau
- MC de Goffau
- MC de Goffau
- ME Mejía-León
- MG Besselink
- MP Burrows
- MS Desai
- MS Petrov
- MW Büchler
- NP Klein
- O Takeuchi
- OO Coker
- P Medveczky
- P Rawla
- PA Banks
- PA Hart
- PG Hogan
- PG Lankisch
- PJ Lee
- PP Hujoel
- R Isenmann
- RA Gaiser
- RF Schwabe
- RM Thomas
- RM Thomas
- Ryan M. Thomas
- RZ Gharaibeh
- RZ Stolzenberg-Solomon
- S Akira
- S Hamada
- S Pushalkar
- S Sharma
- S Tomkovich
- SE Kahn
- SM Jandhyala
- SR Hingorani
- SR Hingorani
- T Conroy
- T Hata
- T Kojima
- T Vatanen
- TS Postler
- TU Greiner
- U Ahmed Ali
- U Sonika
- V Gopalakrishnan
- V Matson
- V Sethi
- VJ Willey
- WHW Tang
- X Fan
- XM Zhang
- Y Hu
- Z Meng
- Z Ren
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Perspectives on ENCODE
- Author
- Abascal Federico
- Acosta Reyes
- Addleman Nicholas J.
- Adrian Jessika
- Afzal Veena
- Ai Rizi
- Aken Bronwen
- Akiyama Jennifer A.
- Amrhein Henry
- Anderson Stacie M.
- Andrews Gregory R.
- Antoshechkin Igor
- Ardlie Kristin G.
- Armstrong Joel
- Astley Matthew
- Banerjee Budhaditya
- Barkal Amira A.
- Barnes If H. A.
- Barozzi Iros
- Barrell Daniel
- Barson Gemma
- Bates Daniel
- Baymuradov Ulugbek K.
- Bazile Cassandra
- Beer Michael A.
- Beik Samantha
- Bender M. A.
- Bennett Ruth
- Bernstein Bradley E.
- Bernstein Bradley E.
- Berry Andrew
- Bhaskar Anand
- Biber Benjamin Van
- Bignell Alexandra
- Blue Steven M.
- Bodine David M.
- Boix Carles
- Boley Nathan
- Borrman Tyler
- Borsari Beatrice
- Bouvrette Louis Philip Benoit
- Boyle Alan P.
- Brandsmeier Laurel A.
- Breschi Alessandra
- Bresnick Emery H.
- Brooks Jason A.
- Buckley Michael
- Burge Christopher B.
- Byron Rachel
- Cahill Eileen
- Cai Lingling
- Cao Lulu
- Carty Mark
- Castanon Rosa G.
- Castillo Andres
- Chaib Hassan
- Chan Esther T.
- Chee Daniel R.
- Chee Sora
- Chen Hao
- Chen Huaming
- Chen Jia-Yu
- Chen Songjie
- Cherry J. Michael
- Cherry J. Michael
- Chhetri Surya B.
- Choudhary Jyoti S.
- Chrast Jacqueline
- Chung Dongjun
- Clarke Declan
- Cody Neal A. L.
- Coppola Candice J.
- Coursen Julie
- Dalton Stephen
- Danyko Cassidy
- Davidson Claire
- Davila-Velderrain Jose
- Davis Carrie A.
- Dekker Job
- Deran Alden
- DeSalvo Gilberto
- Despacio-Reyes Gloria
- Dewey Colin N.
- Dickel Diane E.
- Diegel Morgan
- Diekhans Mark
- Dileep Vishnu
- Ding Bo
- Djebali Sarah
- Dobin Alexander
- Dominguez Daniel
- Donaldson Sarah
- Drenkow Jorg
- Dreszer Timothy R.
- Drier Yotam
- Duff Michael O.
- Dunn Douglass
- D’Ippolito Anthony M.
- Eastman Catharine
- Ecker Joseph R.
- Edwards Matthew D.
- El-Ali Nicole
- Elhajjajy Shaimae I.
- Elkins Keri
- Emili Andrew
- Epstein Charles B.
- Evans Rachel C.
- Ezkurdia Iakes
- Fan Kaili
- Farnham Peggy J.
- Farrell Nina
- Feingold Elise A.
- Feingold Elise A.
- Ferreira Anne-Maud
- Fisher-Aylor Katherine
- Fitzgerald Stephen
- Flicek Paul
- Flicek Paul
- Foo Chuan Sheng
- Fortier Kevin
- Frankish Adam
- Frankish Adam
- Freese Peter
- Fu Shaliu
- Fu Xiang-Dong
- Fu Yu
- Fukuda-Yuzawa Yoko
- Fulciniti Mariateresa
- Funnell Alister P. W.
- Gabdank Idan
- Galeev Timur
- Gao Mingshi
- Garvin Tyler H.
- Gelboin-Burkhart Chelsea Anne
- Georgolopoulos Grigorios
- Gerstein Mark B.
- Gerstein Mark B.
- Giardine Belinda M.
- Gifford David K.
- Gilbert David M.
- Gilchrist Daniel A.
- Gilchrist Daniel A.
- Gillespie Shawn
- Gingeras Thomas R.
- Gingeras Thomas R.
- Giron Carlos Garcia
- Gong Peng
- Gonzalez Alvaro
- Gonzalez Jose M.
- Good Peter
- Goren Alon
- Gorkin David U.
- Graveley Brenton R.
- Graveley Brenton R.
- Gray Michael
- Greenblatt Jack F.
- Griffiths Ed
- Groudine Mark T.
- Grubert Fabian
- Gu Mengting
- Guigó Roderic
- Guo Hongbo
- Guo Yu
- Guo Yuchun
- Gursoy Gamze
- Gutierrez-Arcelus Maria
- Halow Jessica
- Hardison Ross C.
- Hardison Ross C.
- Hardy Matthew
- Hariharan Manoj
- Harmanci Arif
- Harrington Anne
- Harrow Jennifer L.
- Hashimoto Tatsunori B.
- Hasz Richard D.
- Hatan Meital
- Haugen Eric
- Hayes James E.
- He Peng
- He Yupeng
- Heidari Nastaran
- Hendrickson David
- Heuston Elisabeth F.
- Hilton Jason A.
- Hitz Benjamin C.
- Hitz Benjamin C.
- Hochman Abigail
- Holgren Cory
- Hou Lei
- Hou Shuyu
- Hsiao Yun-Hua E.
- Hsu Shanna
- Huang Hui
- Hubbard Tim J.
- Huey Jack
- Hughes Timothy R.
- Hunt Toby
- Ibarrientos Sean
- Issner Robbyn
- Iwata Mineo
- Izuogu Osagie
- Jaakkola Tommi
- Jameel Nader
- Jammal Omar Al
- Jansen Camden
- Jiang Lixia
- Jiang Peng
- Johnson Audra
- Johnson Rory
- Jungreis Irwin
- Kadaba Madhura
- Kasowski Maya
- Kasparian Mary
- Kato Momoe
- Kaul Rajinder
- Kawli Trupti
- Kay Michael
- Keen Judith C.
- Keles Sunduz
- Keller Cheryl A.
- Kelley David
- Kellis Manolis
- Kheradpour Pouya
- Kim Daniel Sunwook
- Kirilusha Anthony
- Klein Robert J.
- Knoechel Birgit
- Kuan Samantha
- Kulik Michael J.
- Kumar Sushant
- Kundaje Anshul
- Kutyavin Tanya
- Lagarde Julien
- Lajoie Bryan R.
- Lambert Nicole J.
- Lazar John
- Lee Ah Young
- Lee Donghoon
- Lee Elizabeth
- Lee Jin Wook
- Lee Kristen
- Leslie Christina S.
- Levy Shawn
- Li Bin
- Li Hairi
- Li Nan
- Li Shantao
- Li Xiangrui
- Li Yang I.
- Li Ying
- Li Yining
- Li Yue
- Lian Jin
- Libbrecht Maxwell W.
- Lin Shin
- Lin Yiing
- Liu Dianbo
- Liu Jason
- Liu Peng
- Liu Tingting
- Liu X. Shirley
- Liu Yan
- Liu Yaping
- Long Maria
- Lou Shaoke
- Loveland Jane
- Lu Aiping
- Lu Yuheng
- Lécuyer Eric
- Ma Lijia
- Mackiewicz Mark
- Mannion Brandon J.
- Mannstadt Michael
- Manthravadi Deepa
- Marinov Georgi K.
- Martin Fergal J.
- Mattei Eugenio
- McCue Kenneth
- McEown Megan
- McVicker Graham
- Meadows Sarah K.
- Meissner Alex
- Mendenhall Eric M.
- Mendenhall Eric M.
- Messer Christopher L.
- Meuleman Wouter
- Meyer Clifford
- Miller Steve
- Milton Matthew G.
- Mishra Tejaswini
- Moore Dianna E.
- Moore Helen M.
- Moore Jill E.
- Moore Jill E.
- Moore Samuel H.
- Moran Jennifer
- Mortazavi Ali
- Mudge Jonathan M.
- Munshi Nikhil
- Murad Rabi
- Myers Richard M.
- Myers Richard M.
- Nandakumar Vivek
- Nandi Preetha
- Narasimha Anil M.
- Narayanan Aditi K.
- Naughton Hannah
- Navarro Fabio C. P.
- Navas Patrick
- Nazarovs Jurijs
- Nelson Jemma
- Neph Shane
- Neri Fidencio Jun
- Nery Joseph R.
- Nesmith Amy R.
- Newberry J. Scott
- Newberry Kimberly M.
- Ngo Vu
- Nguyen Rosy
- Nguyen Thai B.
- Nguyen Tung
- Nishida Andrew
- Noble William S.
- Novak Catherine S.
- Novoa Eva Maria
- Nuñez Briana
- Olson Sara
- Onate Kathrina C.
- Otterman Ericka
- Ozadam Hakan
- O’Donnell Charles W.
- Pagan Michael
- Pagan Michael
- Palden Tsultrim
- Pan Xinghua
- Park Yongjin
- Partridge E. Christopher
- Paten Benedict
- Pauli-Behn Florencia
- Pazin Michael J.
- Pazin Michael J.
- Pei Baikang
- Pennacchio Len A.
- Perez Alexander R.
- Perry Emily H.
- Pervouchine Dmitri D.
- Phalke Nishigandha N.
- Pham Quan
- Phanstiel Doug H.
- Plajzer-Frick Ingrid
- Pratt Gabriel A.
- Pratt Henry E.
- Preissl Sebastian
- Pritchard Jonathan K.
- Pritykin Yuri
- Purcaro Michael J.
- Qin Qian
- Quinones-Valdez Giovanni
- Rabano Ines
- Radovani Ernest
- Raj Anil
- Rajagopal Nisha
- Ram Oren
- Ramirez Lucia
- Ramirez Ricardo N.
- Rausch Dylan
- Raychaudhuri Soumya
- Raymond Joseph
- Razavi Rozita
- Reddy Timothy E.
- Reimonn Thomas M.
- Ren Bing
- Ren Bing
- Reymond Alexandre
- Reynolds Alex
- Rhie Suhn K.
- Rinn John
- Rivera Miguel
- Rivera-Mulia Juan Carlos
- Roberts Brian
- Rodriguez Jose Manuel
- Rozowsky Joel
- Ryan Russell
- Rynes Eric
- Salins Denis N.
- Sandstrom Richard
- Sasaki Takayo
- Sathe Shashank
- Savic Daniel
- Scavelli Alexandra
- Scheiman Jonathan
- Schlaffner Christoph
- Schloss Jeffery A.
- Schmitges Frank W.
- See Lei Hoon
- Sethi Anurag
- Setty Manu
- Shafer Anthony
- Shan Shuo
- Sharon Eilon
- Shen Quan
- Shen Yin
- Sherwood Richard I.
- Shi Minyi
- Shin Sunyoung
- Shoresh Noam
- Siebenthall Kyle
- Sisu Cristina
- Slifer Teri
- Sloan Cricket A.
- Smith Anna
- Snetkova Valentina
- Snyder Michael P.
- Snyder Michael P.
- Spacek Damek V.
- Srinivasan Sharanya
- Srivas Rohith
- Stamatoyannopoulos George
- Stamatoyannopoulos John A.
- Stamatoyannopoulos John A.
- Stanton Rebecca
- Steffan Dave
- Stehling-Sun Sandra
- Strattan J. Seth
- Su Amanda
- Sundararaman Balaji
- Suner Marie-Marthe
- Syed Tahin
- Szynkarek Matt
- Tanaka Forrest Y.
- Tenen Danielle
- Teng Mingxiang
- Thomas Jeffrey A.
- Toffey Dave
- Tress Michael L.
- Trout Diane E.
- Trynka Gosia
- Tsuji Junko
- Upchurch Sean A.
- Ursu Oana
- Uszczynska-Ratajczak Barbara
- Uziel Mia C.
- Valencia Alfonso
- van der Velde Arjan G.
- Van Nostrand Eric L.
- Vaydylevich Yekaterina
- Vazquez Jesus
- Victorsen Alec
- Vielmetter Jost
- Vierstra Jeff
- Visel Axel
- Vlasova Anna
- Vockley Christopher M.
- Volpi Simona
- Vong Shinny
- Wang Hao
- Wang Mengchi
- Wang Qin
- Wang Ruth
- Wang Tao
- Wang Wei
- Wang Xiaofeng
- Wang Yanli
- Watson Nathaniel K.
- Wei Xintao
- Wei Zhijie
- Weisser Hendrik
- Weissman Sherman M.
- Welch Rene
- Welikson Robert E.
- Weng Zhiping
- Weng Zhiping
- Westra Harm-Jan
- Whitaker John W.
- White Collin
- White Kevin P.
- Wildberg Andre
- Williams Brian A.
- Wine David
- Witt Heather N.
- Wold Barbara
- Wolf Maxim
- Wright James
- Xiao Rui
- Xiao Xinshu
- Xu Jie
- Xu Jinrui
- Yan Koon-Kiu
- Yan Yongqi
- Yang Hongbo
- Yang Xinqiong
- Yang Yi-Wen
- Yardımcı Galip Gürkan
- Yee Brian A.
- Yeo Gene W.
- Young Taylor
- Yu Tianxiong
- Yue Feng
- Zaleski Chris
- Zang Chongzhi
- Zeng Haoyang
- Zeng Weihua
- Zerbino Daniel R.
- Zerbino Daniel R.
- Zhai Jie
- Zhan Lijun
- Zhan Ye
- Zhang Bo
- Zhang Jialing
- Zhang Jing
- Zhang Kai
- Zhang Lijun
- Zhang Peng
- Zhang Qi
- Zhang Xiao-Ou
- Zhang Yanxiao
- Zhang Zhizhuo
- Zhao Yuan
- Zheng Ye
- Zhong Guoqing
- Zhou Xiao-Qiao
- Zhu Yun
- Zimmerman Jared
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/07/2020
- Field of study
The Encylopedia of DNA Elements (ENCODE) Project launched in 2003 with the long-term goal of developing a comprehensive map of functional elements in the human genome. These included genes, biochemical regions associated with gene regulation (for example, transcription factor binding sites, open chromatin, and histone marks) and transcript isoforms. The marks serve as sites for candidate cis-regulatory elements (cCREs) that may serve functional roles in regulating gene expression1. The project has been extended to model organisms, particularly the mouse. In the third phase of ENCODE, nearly a million and more than 300,000 cCRE annotations have been generated for human and mouse, respectively, and these have provided a valuable resource for the scientific community.11Nsciescopu
Expanded encyclopaedias of DNA elements in the human and mouse genomes
- Author
- Abascal Federico
- Acosta Reyes
- Addleman Nicholas J.
- Adrian Jessika
- Adrian Jessika
- Afzal Veena
- Ai Rizi
- Aken Bronwen
- Akiyama Jennifer A.
- Amrhein Henry
- Anderson Stacie M.
- Andrews Gregory R.
- Antoshechkin Igor
- Ardlie Kristin G.
- Armstrong Joel
- Astley Matthew
- Banerjee Budhaditya
- Barkal Amira A.
- Barnes If H. A.
- Barozzi Iros
- Barrell Daniel
- Barson Gemma
- Bates Daniel
- Baymuradov Ulugbek K.
- Bazile Cassandra
- Beer Michael A.
- Beik Samantha
- Bender M. A.
- Bennett Ruth
- Bernstein Bradley E.
- Bernstein Bradley E.
- Berry Andrew
- Bhaskar Anand
- Biber Benjamin Van
- Bignell Alexandra
- Blue Steven M.
- Bodine David M.
- Boix Carles
- Boley Nathan
- Borrman Tyler
- Borsari Beatrice
- Bouvrette Louis Philip Benoit
- Boyle Alan P.
- Brandsmeier Laurel A.
- Breschi Alessandra
- Bresnick Emery H.
- Brooks Jason A.
- Buckley Michael
- Burge Christopher B.
- Burge Christopher B.
- Byron Rachel
- Cahill Eileen
- Cai Lingling
- Cao Lulu
- Carty Mark
- Castanon Rosa G.
- Castillo Andres
- Chaib Hassan
- Chan Esther T.
- Chee Daniel R.
- Chee Sora
- Chen Hao
- Chen Huaming
- Chen Jia-Yu
- Chen Songjie
- Cherry J. Michael
- Cherry J. Michael
- Chhetri Surya B.
- Chhetri Surya B.
- Choudhary Jyoti S.
- Chrast Jacqueline
- Chung Dongjun
- Clarke Declan
- Cody Neal A. L.
- Coppola Candice J.
- Coursen Julie
- Dalton Stephen
- Danyko Cassidy
- Davidson Claire
- Davila-Velderrain Jose
- Davis Carrie A.
- Davis Carrie A.
- Dekker Job
- Dekker Job
- Deran Alden
- DeSalvo Gilberto
- Despacio-Reyes Gloria
- Dewey Colin N.
- Dickel Diane E.
- Dickel Diane E.
- Diegel Morgan
- Diekhans Mark
- Dileep Vishnu
- Ding Bo
- Djebali Sarah
- Dobin Alexander
- Dobin Alexander
- Dominguez Daniel
- Donaldson Sarah
- Drenkow Jorg
- Dreszer Timothy R.
- Drier Yotam
- Duff Michael O.
- Dunn Douglass
- D’Ippolito Anthony M.
- Eastman Catharine
- Ecker Joseph R.
- Ecker Joseph R.
- Edwards Matthew D.
- El-Ali Nicole
- Elhajjajy Shaimae I.
- Elhajjajy Shaimae I.
- Elkins Keri
- Emili Andrew
- Epstein Charles B.
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- Fu Yu
- Fukuda-Yuzawa Yoko
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- Funnell Alister P. W.
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- Steffan Dave
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- Tsuji Junko
- Upchurch Sean A.
- Ursu Oana
- Uszczynska-Ratajczak Barbara
- Uziel Mia C.
- Valencia Alfonso
- van der Velde Arjan G.
- Van Nostrand Eric L.
- Van Nostrand Eric L.
- Vaydylevich Yekaterina
- Vazquez Jesus
- Victorsen Alec
- Victorsen Alec
- Vielmetter Jost
- Vierstra Jeff
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- Visel Axel
- Vlasova Anna
- Vockley Christopher M.
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- Vong Shinny
- Wang Hao
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- Wang Qin
- Wang Ruth
- Wang Tao
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- Wang Xiaofeng
- Wang Xiaofeng
- Wang Yanli
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- Wei Xintao
- Wei Xintao
- Wei Zhijie
- Weisser Hendrik
- Weissman Sherman M.
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- Welikson Robert E.
- Weng Zhiping
- Weng Zhiping
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- Williams Brian A.
- Wine David
- Witt Heather N.
- Wold Barbara
- Wold Barbara
- Wolf Maxim
- Wright James
- Xiao Rui
- Xiao Xinshu
- Xu Jie
- Xu Jinrui
- Yan Koon-Kiu
- Yan Yongqi
- Yang Hongbo
- Yang Xinqiong
- Yang Yi-Wen
- Yardımcı Galip Gürkan
- Yee Brian A.
- Yeo Gene W.
- Yeo Gene W.
- Young Taylor
- Yu Tianxiong
- Yue Feng
- Zaleski Chris
- Zang Chongzhi
- Zeng Haoyang
- Zeng Weihua
- Zerbino Daniel R.
- Zhai Jie
- Zhan Lijun
- Zhan Ye
- Zhang Bo
- Zhang Jialing
- Zhang Jialing
- Zhang Jing
- Zhang Jing
- Zhang Kai
- Zhang Lijun
- Zhang Peng
- Zhang Qi
- Zhang Xiao-Ou
- Zhang Xiao-Ou
- Zhang Yanxiao
- Zhang Zhizhuo
- Zhao Yuan
- Zheng Ye
- Zhong Guoqing
- Zhou Xiao-Qiao
- Zhu Yun
- Zimmerman Jared
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/07/2020
- Field of study
AbstractThe human and mouse genomes contain instructions that specify RNAs and proteins and govern the timing, magnitude, and cellular context of their production. To better delineate these elements, phase III of the Encyclopedia of DNA Elements (ENCODE) Project has expanded analysis of the cell and tissue repertoires of RNA transcription, chromatin structure and modification, DNA methylation, chromatin looping, and occupancy by transcription factors and RNA-binding proteins. Here we summarize these efforts, which have produced 5,992 new experimental datasets, including systematic determinations across mouse fetal development. All data are available through the ENCODE data portal (https://www.encodeproject.org), including phase II ENCODE1 and Roadmap Epigenomics2 data. We have developed a registry of 926,535 human and 339,815 mouse candidate cis-regulatory elements, covering 7.9 and 3.4% of their respective genomes, by integrating selected datatypes associated with gene regulation, and constructed a web-based server (SCREEN; http://screen.encodeproject.org) to provide flexible, user-defined access to this resource. Collectively, the ENCODE data and registry provide an expansive resource for the scientific community to build a better understanding of the organization and function of the human and mouse genomes.11Nsciescopu
Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity
- Author
- Aanensen David M
- Abudahab Khalil
- Acheson Erwan
- Adams Alexander
- Adams Helen
- Adriaenssens Evelien M
- Afifi Safiah
- Aggarwal Dinesh
- Ahmad Shazaad SY
- Alam Mohammad T
- Alcolea-Medina Adela
- Alderton Alex
- Alikhan Nabil-Fareed
- Allan John
- Allara Elias
- Amato Roberto
- Andersson Monique
- Angyal Adrienn
- Aranday-Cortes Elihu
- Ariani Cristina
- Asad Hibo
- Asamaphan Patawee
- Ashworth Jordan
- Atkinson Laura
- Attwood Stephen
- Auckland Cressida
- Awan Ali R
- Aydin Alp
- Baker David J
- Baker Paul
- Balcazar Carlos E
- Ball Jonathan
- Barton Edward
- Bashton Matthew
- Batra Rahul
- Baxter Laura
- Beale Mathew A
- Beaver Charlotte
- Beckett Angela
- Beer Robert
- Beggs Andrew
- Bell Andrew
- Bellis Katherine L
- Berger Duncan J
- Berriman Matt
- Berry Lisa
- Berry Louise
- Betancor Gilberto
- Betteridge Emma
- Bewshea Claire M
- Bibby David
- Bicknell Kelly
- Birchley Alec
- Bird Paul
- Bishop Chloe
- Blane Beth
- Bolt Frances
- Bonsall David
- Boswell Tim
- Bosworth Andrew
- Bourgeois Yann
- Boyd Olivia
- Boyes John
- Bradley Declan T
- Bradshaw Daniel
- Breen Cassie
- Bresner Catherine
- Breuer Judith
- Bridgewater Hannah E
- Brooks Tony T
- Broos Alice
- Brown Julianne Rose
- Brown Paul E
- Brown Rebecca
- Brunker Kirstyn
- Bucca Giselda
- Buck David
- Buddenborg Sarah K
- Bull Matthew
- Bull Matthew
- Burton-Fanning Shirelle
- Butcher Ethan
- Caddy Sarah L
- Caller Laura G
- Campbell Sharon
- Carlile Matthew
- Carmichael Stephen N
- Casey Anna
- Castellano Sergi
- Chalker Vicki
- Chand Meera
- Chapman Michael R
- Chappell Joseph G
- Charalampous Themoula
- Charles Ian G
- Chaudhry Yasmin
- Chauhan Anoop J
- Cheng Jeffrey KJ
- Churcher Carol M
- Clark Gemma
- Coll Francesc
- Collins Jennifer
- Colquhoun Rachel
- Colquhoun Rachel M
- Connor Thomas R
- Connor Thomas R
- Constantinidou Chrystala
- Coombes Jason
- Corden Sally
- Cormie Claire
- Cortes Nicholas
- Cortes Nick
- Cottrell Simon
- Coupland Lindsay J
- Cowell Angela
- Cox Alison
- Craine Noel
- Cronin Michelle
- Crooke Derrick
- Curran Martin D
- Curran Tanya
- da Silva Filipe Ana
- da Silva Filipe Ana
- Dabrera Gavin
- Danesh John
- Darby Alistair C
- Davidson Rose K
- Davies Alisha
- Davis Thomas
- de Cesare Mariateresa
- De Lacy Elen
- de Oliveira Martins Leonardo
- de Silva Thushan I
- Debebe Johnny
- Dervisevic Samir
- Dewar Rebecca
- Dias Joana
- Diaz Maria
- Dibling Thomas
- Dorman Matthew J
- Downing Fatima
- Drury Eleanor
- du Plessis Louis
- Duckworth Nichola
- Dyal Patricia L
- Eccles Richard
- Edgeworth Jonathan
- Edwards Sue
- Eldirdiri Sahar
- Ellaby Nicholas
- Ellard Sian
- Elliott Scott
- Eltringham Gary
- Elumogo Ngozi
- Essex Sarah
- Evans Cariad
- Evans Johnathan M
- Eyre David
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- Forrest Leysa M
- Forrest Sally
- Foulser Luke
- Francois Sarah
- Fraser Christophe
- Freeman Timothy M
- Frost Lucy R
- Fuller William
- Gallagher Eileen
- Gallagher Michael D
- Garcia-Casado Maria V
- Gaskin Amy
- Gatica-Wilcox Bree
- Gavriil Artemis
- Geidelberg Lily
- Geidelberg Lily
- Gemmell Matthew
- Georgana Iliana
- George Ryan P
- Gifford Laura
- Gilbert Lauren
- Gill Harmeet K
- Gilroy Rachel AJ
- Girgis Sophia T
- Glaysher Sharon
- Golubchik Tanya
- Goncalves Sonia
- Goodfellow Ian
- Goodfellow Ian G
- Goodwin Scott
- Graham Clive
- Graham Lee
- Gramatopoulos Dimitris
- Green Angie
- Green Luke R
- Greenaway Jane
- Gregory Richard
- Griffith Luke
- Groves Danielle C
- Groves Natalie
- Guest Martyn
- Gulliver Huw
- Gutierrez Ana Victoria
- Hadjirin Nazreen F
- Haldenby Sam T
- Hale Antony D
- Hall Grant
- Halstead Fenella
- Hamilton William L
- Haque Tanzina
- Harper Katherine L
- Harris Kathryn Ann
- Harrison Ewan M
- Harrison Ian
- Harrison James W
- Hartman Hassan
- Hattersley Andrew
- Heaney Judith
- Helmer Thomas
- Hesketh Andrew R
- Heyburn David
- Higginson Ellen E
- Hill Verity
- Hill Verity
- Hilvers Ember
- Hiscox Julian A
- Holden Matthew TG
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- Hopes Richard
- Hosmillo Myra
- Houldcroft Charlotte J
- Howe Robin
- Howson-Wells Hannah C
- Hubb Jonathan
- Hughes Joseph
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- Hunter Adam D
- Hutchings Stephanie
- Impey Robert
- Irish-Tavares Dianne
- Iturriza-Gomara Miren
- Jackson Ben
- Jackson Ben
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- Jackson Kathryn A
- Jahun Aminu S
- James Keith
- Jamrozy Dorota
- Jarrett Ruth
- Jeffries Aaron R
- Jesudason Natasha
- Jesudason Natasha G
- John Michaela
- Johnson Kate
- Johnson Natasha
- Johnson Rob
- Johnson Robert
- Johnston Ian
- Jones Hannah
- Jones Katie
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- Jorgensen David
- Jorgensen David
- Joseph Amelia
- Justice Anita
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- Kenyon Anita
- Kermack Leanne M
- Khakh Manjinder
- Khokhar Fahad A
- Kidd Stephen
- Kingsley Robert A
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- Kolyva Anastasia
- Koshy Cherian
- Kraemer Moritz
- Kristiansen Mark
- Kumziene-Summerhayes Sara
- Kwiatkowski Dominic
- Lackenby Angie
- Langford Cordelia
- Lawniczak Mara
- Le-Viet Thanh
- Lee David
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- Lister Michelle M
- Livett Rich
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- Manesis Nikos
- Manley Robin
- Manso Carmen
- Marchbank Angela
- Martincorena Inigo
- Martinez-Nunez Rocio T
- Masoli Jane AH
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- Mbisa Tamyo
- McCluggage Kathryn
- McClure Patrick C
- McCrone John T
- McCrone JT
- McGuigan Samantha
- McHugh Martin P
- McKenna James P
- McKerr Caoimhe
- McMinn Liz
- McMurray Claire
- Meader Emma J
- Meadows Lizzie
- Menegazzo Mirko
- Meredith Luke W
- Merrick Ian
- Mestek-Boukhibar Lamia
- Miah Shahjahan
- Michell Stephen L
- Michelsen Michelle L
- Molnar Zoltan
- Monaghan Lynn
- Mookerjee Siddharth
- Moore Catherine
- Moore Catrin
- Moore Christopher
- Moore Nathan
- Morgan Mari
- Morgan Sian
- Mori Matilde
- Moses Samuel
- Muir Peter
- Munn Robert
- Myers Richard
- Nascimento Fabricia F
- Nascimento Fabricia F
- Naydenova Plamena
- Neaverson Alexandra S
- Nebbia Gaia
- Nelson Andrew
- Nelson Charlotte
- Nelson Rachel
- Nicholls Sam
- Nicholls Samuel M
- Nichols Jenna
- Niebel Marc O
- Niola Paola
- Nomikou Kyriaki
- O'Toole Elaine
- O'Toole Áine
- Orton Richard J
- Osman Husam
- Ott Sascha
- O’Grady Justin
- O’Toole Áine
- Pacchiarini Nicole
- Pacchiarini Nicole
- Padgett Debra
- Page Andrew J
- Palmer Sophie
- Palmer Steve
- Panchbhaya Yasmin N
- Pandey Sarojini
- Park Naomi
- Parker Matthew D
- Parmar Surendra
- Parr Yasmin A
- Parsons Paul J
- Partridge David G
- Pascall David J
- Patel Gaurang
- Patel Minal
- Patel Vineet
- Paterson Steve
- Payne Brendan AI
- Peacock Sharon J
- Pearson Clare
- Perry Malorie
- Peto Timothy
- Pinckert Malte L
- Platt Steven
- Plimmer Amy
- Poplawski Radoslaw
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- Pybus Oliver G
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- Quail Mike
- Quick Joshua
- Raghwani Jayna
- Ragonnet-Cronin Manon
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- Rajatileka Shavanthi
- Rambaut Andrew
- Rambaut Andrew
- Ramsay Mary
- Randell Paul A
- Raviprakash Veena
- Raza Mohammad
- Resende Silva Paola C
- Rey Sara
- Rey Sara M
- Reynolds Nicola
- Richter Alex
- Robertson David L
- Robertson David L
- Robinson Esther
- Robinson Trevor I
- Robson Samuel C
- Rogers Hazel A
- Rooke Stefan
- Rowan Aileen
- Rowe Will
- Roy Sunando
- Rudder Steven
- Ruis Chris
- Ryan Felicity
- Sambles Christine M
- Sang Fei
- Scarlett Garry P
- Schaefer Ulf
- Scher Emily
- Scott Carol
- Scott Garren
- Sethi Dheeraj K
- Shaaban Sharif
- Shah Divya
- Shah Rajiv
- Shah Rajiv N
- Shankar Giri
- Shaw Robert
- Shepherd James
- Shepherd James G
- Sheriff Nicola
- Shirley Lesley
- Signell Adrian W
- Sillitoe John
- Simpson David A
- Singer Joshua B
- Sivaprakasam Venkat
- Siveroni Igor
- Siveroni Igor
- Sloan Tim J
- Sluga Graciela
- Smith Christen
- Smith Colin P
- Smith Darren L
- Smith Nikki
- Smith Wendy
- Smollett Katherine L
- Snell Luke B
- Souster Emily
- Southgate Joel
- Southgate Joel
- Spellman Karla
- Spencer-Chapman Michael
- Sridhar Sushmita
- Stanley Rachael
- Stanton Thomas D
- Starinskij Igor
- Stark Richard
- Stockton Joanne
- Stuart Claire
- Studholme David J
- Swindells Emma
- Swingler Tracey
- Taha Yusri
- Tang Julian
- Taylor Ben EW
- Taylor Graham P
- Taylor Sarah
- Taylor-Joyce Grace
- Tedim Ana P
- Temperton Ben
- Templeton Kate E
- Thompson Thomas
- Thomson Emma C
- Thomson Emma C
- Thomson Nicholas M
- Thornton Alicia
- Thurston Scott
- Todd John A
- Tong Lily
- Tonkin-Hill Gerry
- Torok M Estee
- Trebes Amy
- Trotter Alexander J
- Tsoleridis Theocharis
- Tucker Rachel M
- Turtle Lance
- Tutill Helena J
- Underwood Anthony P
- Unnikrishnan Meera
- Vamos Edith E
- Vasylyeva Tetyana
- Vattipally Sreenu
- Vipond Ian B
- Volz Erik
- Volz Erik M
- Wain John
- Walsh Sarah
- Wang Dennis
- Wantoch Michelle
- Warne Ben
- Warwick-Dugdale Joanna
- Wastenge Elizabeth
- Watkins Joanne
- Watts Joanne
- Waugh Sheila
- Webber Mark A
- Weeks Sam
- Weldon Danni
- Whitehead Mark
- Williams Charlotte A
- Williams Chris
- Williams David
- Williams Rachel J
- Williams Rebecca
- Williams Thomas
- Williamson Kathleen A
- Willingham Iona
- Wilson Harry D
- Wise Emma
- Workman Trudy
- Wright Victoria
- Wyles Matthew
- Wyllie Sarah
- Yakovleva Anna
- Yasir Muhammad
- Yeats Corin A
- Yew Wen C
- Young Gregory R
- Young Jamie
- Yu Xiaoyu
- Zarebski Alex
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2021
- Field of study
Global dispersal and increasing frequency of the SARS-CoV-2 spike protein variant D614G are suggestive of a selective advantage but may also be due to a random founder effect. We investigate the hypothesis for positive selection of spike D614G in the United Kingdom using more than 25,000 whole genome SARS-CoV-2 sequences. Despite the availability of a large dataset, well represented by both spike 614 variants, not all approaches showed a conclusive signal of positive selection. Population genetic analysis indicates that 614G increases in frequency relative to 614D in a manner consistent with a selective advantage. We do not find any indication that patients infected with the spike 614G variant have higher COVID-19 mortality or clinical severity, but 614G is associated with higher viral load and younger age of patients. Significant differences in growth and size of 614G phylogenetic clusters indicate a need for continued study of this variant
Metabolism of Oxalate in Humans: A Potential Role Kynurenine Aminotransferase/Glutamine Transaminase/Cysteine Conjugate Betalyase Plays in Hyperoxaluria
- Author
- Abraham D.G.
- Akladios F.N.
- Alberati-Giani D.
- Alkondon M.
- Aronson P.S.
- Asplin J.R.
- Auer B.L.
- Baker P.R.
- Baran H.
- Bardouri M.
- Berardi M.J.
- Birch P.J.
- Birdsey G.M.
- Birdsey G.M.
- Cai L.
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- Publication venue
- 'Bentham Science Publishers Ltd.'
- Publication date
- Field of study