1,852 research outputs found

    A note on Berezin-Toeplitz quantization of the Laplace operator

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    Given a Hodge manifold, it is introduced a self-adjoint operator on the space of endomorphisms of the global holomorphic sections of the polarization line bundle. Such operator is shown to approximate the Laplace operator on functions when composed with Berezin-Toeplitz quantization map and its adjoint up to an error which tends to zero when taking higher powers of the polarization line bundle

    Scalar curvature and asymptotic Chow stability of projective bundles and blowups

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    The holomorphic invariants introduced by Futaki as obstruction to the asymptotic Chow semistability are studied by an algebraic-geometric point of view and are shown to be the Mumford weights of suitable line bundles on the Hilbert scheme. These invariants are calculated in two special cases. The first is a projective bundle over a curve of genus at least two, and it is shown that it is asymptotically Chow polystable (with every polarization) if and only the underlying vector bundle is slope polystable. This proves a conjecture of Morrison with the extra assumption that the involved polarization is sufficiently divisible. Moreover it implies that a projective bundle is asymptotically Chow polystable (with every polarization) if and only if it admits a constant scalar curvature Kaehler metric. The second case is a manifold blown-up at points, and new examples of asymptotically Chow unstable constant scalar curvature Kaehler classes are given.Comment: 15 page

    PIntron: a Fast Method for Gene Structure Prediction via Maximal Pairings of a Pattern and a Text

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    Current computational methods for exon-intron structure prediction from a cluster of transcript (EST, mRNA) data do not exhibit the time and space efficiency necessary to process large clusters of over than 20,000 ESTs and genes longer than 1Mb. Guaranteeing both accuracy and efficiency seems to be a computational goal quite far to be achieved, since accuracy is strictly related to exploiting the inherent redundancy of information present in a large cluster. We propose a fast method for the problem that combines two ideas: a novel algorithm of proved small time complexity for computing spliced alignments of a transcript against a genome, and an efficient algorithm that exploits the inherent redundancy of information in a cluster of transcripts to select, among all possible factorizations of EST sequences, those allowing to infer splice site junctions that are highly confirmed by the input data. The EST alignment procedure is based on the construction of maximal embeddings that are sequences obtained from paths of a graph structure, called Embedding Graph, whose vertices are the maximal pairings of a genomic sequence T and an EST P. The procedure runs in time linear in the size of P, T and of the output. PIntron, the software tool implementing our methodology, is able to process in a few seconds some critical genes that are not manageable by other gene structure prediction tools. At the same time, PIntron exhibits high accuracy (sensitivity and specificity) when compared with ENCODE data. Detailed experimental data, additional results and PIntron software are available at http://www.algolab.eu/PIntron
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