482 research outputs found
Effects of Hyperbolic Rotation in Minkowski Space on the Modeling of Plasma Accelerators in a Lorentz Boosted Frame
Laser driven plasma accelerators promise much shorter particle accelerators
but their development requires detailed simulations that challenge or exceed
current capabilities. We report the first direct simulations of stages up to 1
TeV from simulations using a Lorentz boosted calculation frame resulting in a
million times speedup, thanks to a frame boost as high as gamma=1300. Effects
of the hyperbolic rotation in Minkowski space resulting from the frame boost on
the laser propagation in the plasma is shown to be key in the mitigation of a
numerical instability that was limiting previous attempts
Modeling laser wakefield accelerators in a Lorentz boosted frame
Modeling of laser-plasma wakefield accelerators in an optimal frame of
reference \cite{VayPRL07} is shown to produce orders of magnitude speed-up of
calculations from first principles. Obtaining these speedups requires
mitigation of a high-frequency instability that otherwise limits effectiveness
in addition to solutions for handling data input and output in a
relativistically boosted frame of reference. The observed high-frequency
instability is mitigated using methods including an electromagnetic solver with
tunable coefficients, its extension to accomodate Perfectly Matched Layers and
Friedman's damping algorithms, as well as an efficient large bandwidth digital
filter. It is shown that choosing the frame of the wake as the frame of
reference allows for higher levels of filtering and damping than is possible in
other frames for the same accuracy. Detailed testing also revealed
serendipitously the existence of a singular time step at which the instability
level is minimized, independently of numerical dispersion, thus indicating that
the observed instability may not be due primarily to Numerical Cerenkov as has
been conjectured. The techniques developed for Cerenkov mitigation prove
nonetheless to be very efficient at controlling the instability. Using these
techniques, agreement at the percentage level is demonstrated between
simulations using different frames of reference, with speedups reaching two
orders of magnitude for a 0.1 GeV class stages. The method then allows direct
and efficient full-scale modeling of deeply depleted laser-plasma stages of 10
GeV-1 TeV for the first time, verifying the scaling of plasma accelerators to
very high energies. Over 4, 5 and 6 orders of magnitude speedup is achieved for
the modeling of 10 GeV, 100 GeV and 1 TeV class stages, respectively
Speeding up simulations of relativistic systems using an optimal boosted frame
It can be computationally advantageous to perform computer simulations in a
Lorentz boosted frame for a certain class of systems. However, even if the
computer model relies on a covariant set of equations, it has been pointed out
that algorithmic difficulties related to discretization errors may have to be
overcome in order to take full advantage of the potential speedup. We summarize
the findings, the difficulties and their solutions, and show that the technique
enables simulations important to several areas of accelerator physics that are
otherwise problematic, including self-consistent modeling in three-dimensions
of laser wakefield accelerator stages at energies of 10 GeV and above.Comment: To be published in the proceedings of DPF-2009, Detroit, MI, July
2009, eConf C09072
Quasi-monoenergetic femtosecond photon sources from Thomson Scattering using laser plasma accelerators and plasma channels
Narrow bandwidth, high energy photon sources can be generated by Thomson
scattering of laser light from energetic electrons, and detailed control of the
interaction is needed to produce high quality sources. We present analytic
calculations of the energy-angular spectra and photon yield that parametrize
the influences of the electron and laser beam parameters to allow source
design. These calculations, combined with numerical simulations, are applied to
evaluate sources using conventional scattering in vacuum and methods for
improving the source via laser waveguides or plasma channels. We show that the
photon flux can be greatly increased by using a plasma channel to guide the
laser during the interaction. Conversely, we show that to produce a given
number of photons, the required laser energy can be reduced by an order of
magnitude through the use of a plasma channel. In addition, we show that a
plasma can be used as a compact beam dump, in which the electron beam is
decelerated in a short distance, thereby greatly reducing radiation shielding.
Realistic experimental errors such as transverse jitter are quantitatively
shown to be tolerable. Examples of designs for sources capable of performing
nuclear resonance fluorescence and photofission are provided
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Application of Videomicroscopy to In-Situ Studies of Zinc Electrodepostion
Arcanobacterium hemolyticum: identification and susceptibility to nine antimicrobial agents
AbstractObjective To evaluate the in vitro spectrum and activity of linezolid, a recent oxazolidinone, according to well-controlled surveillance data from 42 medical centers in 13 countries throughout Europe.Methods Participants tested the susceptibility of 125 clinical strains of enterococcal and staphylococcal species against 13 drugs using reference broth microdilution trays or the standardized disk diffusion method of the National Committee for Clinical Laboratory Standards (NCCLS). Streptococcal species (n = 25 at each center) were tested against six drugs using E test (AB BIODISK, Solna, Sweden). Quality assurance testing was conducted using NCCLS-recommended strains and verification of resistance to linezolid and other selected agents was performed by retesting strains at the regional (Europe) and international (USA) monitor sites.Results A total of 5598 strains from throughout Europe (91% compliance) were tested. Vancomycin resistance was reported in only 0.6 and 3.0% of Enterococcus faecalis and E. faecium, respectively. Penicillin resistance occurred in 25.1% of Streptococcus pneumoniae; 4.9% at the high-level (≥2 mg/L). The MIC90 for linezolid was 1 mg/L for streptococci and 2 mg/L for enterococci and staphylococci. Using the US FDA- and EUCAST-recommended susceptible breakpoints for linezolid, there were no confirmed reports of linezolid resistance [minimum inhibitory concentration (MIC), ≥8mg/L]. The distribution of linezolid MIC values was unimodal and varied between 0.25 and 1 mg/L for streptococci (≥90% of isolates), and between 1 and 2 mg/L for staphylococci (≥90%) and enterococci (≥95%). There were no differences in linezolid susceptibility in the vancomycin-, oxacillin-, or penicillin-resistant subsets of strains when compared to susceptible organism populations.Conclusions Compared to the North American component of this study, there was substantially less vancomycin resistance among E. faecium isolates (Europe 3.0% vs. North America 63.4%). While the occurrence of penicillin-resistant S. pneumoniae in Europe and North America was similar (25.1% vs. 29.7%), the recovery of high-level penicillin-resistant strains was nearly three-fold higher in North America (4.9% vs. 13.2%). Only linezolid was universally active against all the tested Gram-positive isolates at ≤4mg/L
Computational accelerator science needs towards laser-plasma accelerators for future colliders
Laser plasma accelerators have the potential to reduce the size of future
linacs for high energy physics by more than an order of magnitude, due to their
high gradient. Research is in progress at current facilities, including the
BELLA PetaWatt laser at LBNL, towards high quality 10 GeV beams and staging of
multiple modules, as well as control of injection and beam quality. The path
towards high-energy physics applications will likely involve hundreds of such
stages, with beam transport, conditioning and focusing. Current research
focuses on addressing physics and R&D challenges required for a detailed
conceptual design of a future collider. Here, the tools used to model these
accelerators and their resource requirements are summarized, both for current
work and to support R&D addressing issues related to collider concepts
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