46 research outputs found
Leadership in a Digitalized and Crisis-ridden World: Towards a Comprehensive Overview of Relevant Competencies for Leaders
Our environment is increasingly characterized by digitalization and crisis. Consequently, the competence requirements for executives are changing. Since they are critical to the success of companies, identifying talents and developing necessary leadership competencies is essential. To accomplish this in a targeted manner, a competency overview is needed that considers digitalization and crisis. However, current literature indicates that digital and crisis leadership are investigated separately. To address this research gap, this study develops a competence overview based on a systematic literature review considering both research streams. The analysis of 38 studies reveals 21 competence areas. For a structured analysis, these competence areas are considering the competence categories of self-, people-, and business management. The literature review shows that there is overlap in the two areas regarding competencies related to decision-making, communication, and learning. Differences occur, for example, regarding leaders' health awareness or technical literacy, which are only addressed in digital leadership
Leadership in a digitalized and crisis-ridden world: towards a comprehensive overview of relevant competencies for leaders
Our environment is increasingly characterized by digitalization and crisis. Consequently, the competence requirements for executives are changing. Since they are critical to the success of companies, identifying talents and developing necessary leadership competencies is essential. To accomplish this in a targeted manner, a competency overview is needed that considers digitalization and crisis. However, current literature indicates that digital and crisis leadership are investigated separately. To address this research gap, this study develops a competence overview based on a systematic literature review considering both research streams. The analysis of 38 studies reveals 21 competence areas. For a structured analysis, these competence areas are considering the competence categories of self-, people-, and business management. The literature review shows that there is overlap in the two areas regarding competencies related to decision-making, communication, and learning. Differences occur, for example, regarding leaders' health awareness or technical literacy, which are only addressed in digital leadership
Personal Skills in the BISE Curriculum: An Integrative Approach
In an increasingly complex and dynamic world, young executives need certain soft skills to be forearmed for the challenges of their job. The need for training of these personal skills in higher education is recognized among the business and information systems engineering (BISE) society. Yet, existing approaches often integrate the development of soft skills implicitly, usually without quantitively measuring the impact on students. However, an initial literature review identified a demand for an explicit and systematic integration of personal skills in basic lectures. We present an approach that systematically integrates the training of personal skills in a basic BISE lecture for first-semester students. To exemplify this approach, we describe the integration of the selfleadership strategy self-observation in a lecture on process modeling. Our research project follows the Design Science Research methodology. The outlook previews the completion of the first design cycle by describing the planned evaluation and further research ideas
LEADERSHIP EDUCATION IN A TECHNOLOGY-ENHANCED LEARNING ENVIRONMENT: THE RELATION BETWEEN SELF-REGULATED LEARNING AND SELF-LEADERSHIP
Our increasingly complex and dynamic environment demands comprehensive self-regulatory skills from university graduates. Self-regulation summarizes the ability to set goals, monitor progress, and adopt behavior purposefully. In an increasingly technology-enhanced learning environment, IS research has already explored approaches to promote self-regulation in students\u27 learning activities. However, it is unclear whether this self-regulated learning (SRL) prepares students for leadership roles. To address this research gap, we gather survey data and apply multiple regression analysis to examine how SRL strategy usage is linked to self-leadership (SL) strategy usage. Our results suggest that behavioral SL strategies are related to the usage of SRL strategies, e.g., the SL strategy âself-rewardingâ to the SRL strategy ârepeatingâ. In contrast, SL strategies such as âmental imageryâ are unrelated to SRL. Based on these findings, we suggest a target-oriented use of digital technologies to foster SL and reveal the need to promote SL strategies like âmental imageryâ separately
Leadership education in a technology-enhanced learning environment
Our increasingly complex and dynamic environment demands comprehensive self-regulatory skills from university graduates. Self-regulation summarizes the ability to set goals, monitor progress, and adopt behavior purposefully. In an increasingly technology-enhanced learning environment, IS research has already explored approaches to promote self-regulation in students' learning activities. However, it is unclear whether this self-regulated learning (SRL) prepares students for leadership roles. To address this research gap, we gather survey data and apply multiple regression analysis to examine how SRL strategy usage is linked to self-leadership (SL) strategy usage. Our results suggest that behavioral SL strategies are related to the usage of SRL strategies, e.g., the SL strategy âself-rewardingâ to the SRL strategy ârepeatingâ. In contrast, SL strategies such as âmental imageryâ are unrelated to SRL. Based on these findings, we suggest a target-oriented use of digital technologies to foster SL and reveal the need to promote SL strategies like âmental imageryâ separately
Untersuchung zur Expression der Integrin-Untereinheiten α2, α3, α6, β1 und β4 beim Plattenepithelkarzinom des Ăsophagus
Integrin Expression in Esophageal Squamous Cell Carcinoma: Loss of the Physiological Integrin Expression Pattern Correlates with Disease Progression
Rapid RT-PCR identification of SARS-CoV-2 in screening donors of fecal microbiota transplantation
Since its first appearance in late 2019 in Wuhan, China, severe acute respiratory syndrome caused by Coronavirus 2 (SARS-CoV-2) has had a major impact on healthcare facilities around the world. Although in the past year, mass vaccination and the development of monoclonal antibody treatments have reduced the number of deaths and severe cases, the circulation of SARS-CoV-2 remains high. Over the past two years, diagnostics have played a crucial role in virus containment both in health care facilities and at the community level. For SARS-CoV-2 detection, the commonly used specimen type is the nasopharyngeal swab, although the virus can be identified in other matrices such as feces. Since fecal microbiota transplantation (FMT) assumes significant importance in the treatment of chronic gut infections and that feces may be a potential vehicle for transmission of SARS-CoV-2, in this study we have evaluated the performance of the rapid cartridge-based RT-PCR test STANDARD⢠M10 SARS-CoV-2 (SD Biosensor Inc., Suwon, South Korea) using fecal samples. The results obtained indicates that STANDARD⢠M10 SARS-CoV-2 can detect SARS-CoV-2 in stool samples even at low concentration. For this reason, STANDARD⢠M10 SARS-CoV-2 could be used as reliable methods for the detection of SARS-CoV-2 in fecal samples and for the screening of FMT donors
Targeting abundant survivin expression in liposarcoma: subtype dependent therapy responses to YM155 treatment
Purpose Liposarcoma (LPS) represent the largest group of malignant soft tissue tumours comprising a heterogeneous group of subtypes in which the degrees of chemoresistance and radiosensitivity strongly vary. Consequently, it is of utmost interest to establish novel therapeutic regimens based on molecular targets. Methods Immunohistochemical staining of survivin was performed in tissue microarrays comprising 49 primary LPS specimens. LPS cell lines were treated with survivin antagonist YM155 and doxorubicin or etoposide alone as well as in combination. Changes in cell viability were investigated and the synergistic effect of a combined therapy analysed. Results Immunohistochemistry revealed an abundant expression of survivin in LPS that significantly concurred with less-differentiated tumour subtypes and grading. In vitro, we demonstrated the impact of the survivin inhibitor YM155 on dedifferentiated LPS (DDLPS) and, even more imposing, pleomorphic LPS (PLS) tumour cell viability with a strong induction of apoptosis. A combined treatment of doxorubicin or etoposide with YM155 augmented the cytotoxic effects on DDLPS and PLS cells. Conclusion These findings support the significant role of survivin in the oncogenesis and progression of LPS subtypes providing a rationale to target survivin in eligible in-vivo models and to pioneer clinical applications of survivin-specific substances unfolding their therapeutic potential in LPS patients prospectively