The European Hematology Association Roadmap for European Hematology Research: a consensus document

The European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical and scientific needs in those areas to enable better funded, more focused European hematology research. Initiated by the EHA, around 300 experts contributed to the consensus document, which will help European policy makers, research funders, research organizations, researchers, and patient groups make better informed decisions on hematology research. It also aims to raise public awareness of the burden of blood disorders on European society, which purely in economic terms is estimated at €23 billion per year, a level of cost that is not matched in current European hematology research funding. In recent decades, hematology research has improved our fundamental understanding of the biology of blood disorders, and has improved diagnostics and treatments, sometimes in revolutionary ways. This progress highlights the potential of focused basic research programs such as this EHA Roadmap. The EHA Roadmap identifies nine ‘sections’ in hematology: normal hematopoiesis, malignant lymphoid and myeloid diseases, anemias and related diseases, platelet disorders, blood coagulation and hemostatic disorders, transfusion medicine, infections in hematology, and hematopoietic stem cell transplantation. These sections span 60 smaller groups of diseases or disorders. The EHA Roadmap identifies priorities and needs across the field of hematology, including those to develop targeted therapies based on genomic profiling and chemical biology, to eradicate minimal residual malignant disease, and to develop cellular immunotherapies, combination treatments, gene therapies, hematopoietic stem cell treatments, and treatments that are better tolerated by elderly patients

Measuring proactive and reactive helping ::development of a scale

We elaborate on the theoretical framework of proactive and reactive helping behavior by positing fou r dimensions. To construct a scale, we g enerated and tested items using an online sample. We established construct and discriminant validity with established constructs. We replicated item characteristics in a subsequent study

Interaction Effects in Cross-Lagged Panel Models: SEM with Latent Interactions Applied to Work-Family Conflict, Job Satisfaction, and Gender

International audienceResearchers often combine longitudinal panel data analysis with tests of interactions (i.e., moderation). A popular example is the cross-lagged panel model (CLPM). However, interaction tests in CLPMs and related models require caution because stable (i.e., between-level, B) and dynamic (i.e., within-level, W) sources of variation are present in longitudinal data, which can conflate estimates of interaction effects. We address this by integrating literature on CLPMs, multilevel moderation, and latent interactions. Distinguishing stable B and dynamic W parts, we describe three types of interactions that are of interest to researchers: 1) purely dynamic or WxW; 2) cross-level or BxW; and 3) purely stable or BxB. We demonstrate estimating latent interaction effects in a CLPM using a Bayesian SEM in Mplus to apply relationships among work-family conflict and job satisfaction, using gender as a stable B variable. We support our approach via simulations, demonstrating that our proposed CLPM approach is superior to a traditional CLPMs that conflate B and W sources of variation. We describe higher-order nonlinearities as a possible extension, and we discuss limitations and future research directions

Multiple team membership arrangements: putting the worker front and center

There are indicators we are entering a new era for MTM research, by moving beyond the structural approach that has characterized MTM research to date, to focus on important and under-researched issues, such as the nature of employees’ experiences in an MTM context. Although team research suggests that the experiences of members impact team functioning, these lines of reasoning have not, until recently, made their way to MTM research. To overcome this limitation, this symposium showcases five papers that use a variety of theoretical perspectives, research designs (i.e., qualitative, quantitative), contexts (e.g., healthcare, automotive manufacturer, online panels), methodologies, and analytical methods (i.e., meta-analysis, content/thematic analysis). The symposium focuses on surfacing and advancing unanswered questions that extend theory and can offer fruitful directions for MTM research by examining critical individual and team level outcomes (e.g., individual/team performance, individual counterproductive and organizational citizenship behavior, individual learning, individual turnover intentions, organizational commitment) in the experiences of MTM employees across their teams (e.g., goals, functions, roles). We hope to provide a forum to advance unanswered questions that offer fruitful directions for MTM research