Recent advances in quartz crystal microbalance-based sensors

10.1155/2011/571405Journal of Sensors2011

Non-invasive glucose monitoring technology in diabetes management: A review

10.1016/j.aca.2012.03.043Analytica Chimica Acta75016-27ACAC

Multisubstrate-compatible ELISA procedures for rapid and high-sensitivity immunoassays

10.1038/nprot.2011.304Nature Protocols64439-44

Evaluation of apparent non-specific protein loss due to adsorption on sample tube surfaces and/or altered immunogenicity

10.1039/c0an00689kAnalyst13671406-1411ANAL

Review of Quantum Dot Technologies for Cancer Detection and Treatment

Semiconductor quantum dots (QDs) are nanoparticles that have attracted widespread interest in biology and medicine due to their unique optical and electronic properties. These properties, especially their reduced tendency to photobleach and the dependence of their fluorescence wavelength on their size, make them suitable for fluorescent probing applications to detect cancer biomarkers in vitro and in vivo in cells/tissues/whole body. There is considerable interest among researchers due to the recent developments in QD technology. QDs have been encapsulated in amphiphilic polymers and bound to tumor-targeting ligands and drug delivery vesicles for targeting, imaging and treating tumor cells. Present efforts are focussed on exploring the massive multiplexing capabilities of the QDs for the simultaneous detection of multiple cancer biomarkers in blood assays and cancer tissue biopsies. These advances in the QD technology have unravelled a great deal of information about the molecular events in tumor cells and early diagnosis of cancer

Quantification of Human Immunoglobulin G Immobilised of Gold Coated Silicon Chip for Biosensing Applications

The most important aspect of biosensor development with high sensitivity is the oriented immobilization of antibodies on the solid substrate. Human IgG was immobilized on gold-coated silicon employing protein A, protein G and neutravidin immobilization procedures. The amount of human IgG immobilized was analyzed by 3, 3ƍ, 4, 4ƍ- tetramethyl benzidine (TMB) substrate assay and was maximum when protein A immobilization procedure was followed. Human IgG coated biosensing surface was regenerated by treatment with glycine-HCl buffer (50 mM, pH 2.2). Atomic force microscopy was used to analyze the distribution of biomolecules immobilized on gold-coated silicon. Our study indicates that human IgG molecules were uniformly bound to gold-coated silicon by protein A immobilization procedur

Technology behind commercial devices for blood glucose monitoring in diabetes management: A review

10.1016/j.aca.2011.07.024Analytica Chimica Acta7032124-136ACAC

Rapid and simple preparation of a reagentless glucose electrochemical biosensor

10.1039/c2an35128eAnalyst137163800-3805ANAL