Adaptive computer technology for people with disabilities

This article discusses one of the most urgent problems of the world - the problem of social integration and adaptation of people with disabilities. The modern adaptive technology for people with different kinds of restrictions and possible prospects for development in this areaВ данной статье рассматривается одна из самых актуальных проблем мира - проблема социальной интеграции и адаптации людей с ограниченными возможностями здоровья. Описаны современные адаптивные технологии для людей с разными видами ограничений и возможные перспективы развития в данной сфер

The application of information and communication technologies for professional self-school students

Currently in Russia to young people facing new challenges for future professional activities. Their essence is that in order to realize their professional plans graduates of schools, secondary and higher education establishments must have knowledge and skills that would help them to quickly reorient themselves in case of changes in the labor market or job lossВ настоящее время в России перед молодыми людьми ставятся новые задачи для дальнейшей профессиональной деятельности. Суть их заключается в том, что для реализации своих профессиональных планов выпускникам школы, средних и высших учебных заведений необходимо обладать знаниями и умениями, которые помогли бы им быстро переориентироваться в случаях изменения ситуации на рынке труда или потери работ

Anthrax: Epidemiological and Epizootiological Situation in 2015, Prognosis for 2016

Outlined are the results of assessment of epidemiological and epizootiological situation on anthrax across the globe in 2015. Three human cases of cutaneous anthrax were registered in the Russian Federation. Detected were two epizootic foci with three cases of live-stock animal disease. 1-20 cases of anthrax in humans are forecasted in the Russian Federation in 2016. Adverse as regards anthrax situation is created in a number of near and far abroad counties. The highest morbidity rates among animals and humans are reported from Asian and African countries. Discussed are the results of investigation into the blunder of the US Department of Defense laboratory system, resulted in distribution of ineffectively decontaminated samples of anthrax agent to the US laboratories, as well as of other states within the past twenty years

Epidemiological and Epizootiological Situation on Anthrax in 2014, and Prognosis for 2015

Presented are the results of analysis of epidemiological and epizootiological situation on anthrax across the Russian Federation and around the world in 2014. Anthrax morbidity rates in Russia have increased as compared to the previous year, but have not exceeded the range of annual variations within the past decade. Three foci of animal infection have been detected here. Unfavorable, as regards anthrax, situation has developed in the CIS countries and the territories beyond. In Europe the cases of deliveries of meat and meat products contaminated with anthrax agent to retail store network have taken place. 1 to 20 cases of anthrax among the population are forecasted in Russia for 2015

New Genetic Markers for Molecular Typing of Bacillus anthracis Strains

Objective: Identification of new markers for the molecular typing of Bacillus anthracis. Materials and methods. The genomes of 16 B. anthracis strains from the collection of the Stavropol Research Anti-Plague Institute, 11 B. anthracis strains and 5 strains of Bacillus cereus from GenBank were investigated. The methods of in vitro and in silico analysis of canonical and whole-genome single nucleotide polymorphisms (SNP), genome regions with variable number of tandem repeats (VNTR) were used for the analysis. Results and discussion. It has been established that there are deletions and (or) SNPs in some of B. anthracis strains of the main genetic lineage B, within the homologous genes of the tri-cistronic operon gerH, which encodes spore germination proteins. gerA genes contain the Bams34 VNTR locus, the sizes of genes in different strains vary due to the different number of tandem repeats and the presence of indels, which suggests the variability of GerA spore germination proteins. In the area of reverse primer annealing, some of them have several SNPs or deletions, which makes impossible PCR amplification of the Bams34 locus. Previously not described VNTR locus, SNPs and indels in sequences of plasmids pXO1 and pXO2, as well as SNP in chromosomal gene of glycerol-3-phosphate transporter were identified. Two pairs of PCR primers for the variable regions of the plasmids were designed. VNTR-locus, SNP and indels in sequences of plasmids pXO1 and pXO2 are suitable genetic markers for the differentiation of typical virulent diplasmid strains belonging to the main genetic lineages of B. anthracis A, B and C. The allele T of SNP within chromosomal glpT gene is specific for one of two strains isolated during the outbreak of anthrax and distinguishes it from all other strains of B. anthracis

BIOLOGICAL PROPERTIES AND MOLECULAR-GENETIC CHARACTERISTICS OF BACILLUS ANTHRACIS STRAINS, ISOLATED DURING THE OUTBREAK OF ANTHRAX IN THE YAMALO-NENETS AUTONOMOUS DISTRICT IN 2016

Objective of the study was to identify phenotypic properties and genetic peculiarities of Bacillus anthracis strains, isolated during the outbreak of anthrax in the territory of Yamal in 2016. Materials and methods. Investigated were the strains of anthrax agent, applying basic and subsequent identification tests and canSNP-, MLVA-genotyping methods and whole genome sequencing. Results and conclusions. The results showed the identity of the phenotypic properties, canSNPand MLVA25-genotypes, and profiles of whole genome-sequencing, regardless of the source of the strains isolation. Confirmed was a common source of human infection. Defined were phylogenetic interrelations of the tested strains and their position in global B. anthracis population. For the first time ever explored was variability of the gene pattern, associated with pathogenicity, and demonstrated – the efficiency of the proposed algorithm for genetic typing

ИТОГИ ФУНКЦИОНИРОВАНИЯ ЕДИНОЙ ГОСУДАРСТВЕННОЙ СИСТЕМЫ КОНТРОЛЯ И УЧЕТА ИНДИВИДУАЛЬНЫХ ДОЗ ОБЛУЧЕНИЯ ГРАЖДАН РОССИЙСКОЙ ФЕДЕРАЦИИ ПО ДАННЫМ ЗА 2014 Г.

The article presents the outcomes of the generalized analysis of personnel, patients and population radiation doses information obtained from the Unified System of Individual Dose Control (USIDC) for 2014. The analysis is conducted on the basis of the annual information from the forms of Federal State Statistical Observation No.1-DOZ, No.2-DOZ, No.3-DOZ and No.4-DOZ. The information is submitted by the organizations and territories accountable to Federal Service for Surveillance on Consumer Rights Protection and Human Well-Being – ROSPOTREBNADZOR.According to No. 1-DOZ data the total number of organizations which submitted the information about personnel dose exposure in 2014 amounted to 16424, with the total headcount of 130688 employees. The average radiation dose of group A personnel was 1,13 mSv/annum. The collective personnel radiation doze totalled 132,5 man-Sv/annum.According to No.3-DOZ data 261 mln X-ray diagnostics were conducted in Russian Federation in 2014. The average medical radiation dose per capita was 0,46 mSv/annum and collective population dose was 66883.4 man-Sv/annum. Computer tomography makes the highest contribution into collective population radiation dose (40,3% ).According to the forms of statistical reporting No. 4-DOZ for 2014 in Russian Federation the population’s average effective dose from natural ionizing radiation sources amounted to 3.48 mSv/annum. The population’s annual effective radiation dose from natural sources of ionizing radiation includes about 59% of radon isotopes and progeny. In 2014 the data was submitted about job-specific doses of 5651 employees from 50 enterprises located in 18 regions of Russia. The values of job-specific radiation of these enterprises’ employees ranged between 0.01 and 3,42 mSv/annum.The article includes the Annexes with final generalized forms of Unified System of Individual Dose Control based on the forms of statistical observations No. 1-, 2- and 4-DOZ.В статье представлены результаты обобщенного анализа сведений о дозах облучения персонала, пациентов и населения, полученных по данным Единой государственной системы контроля и учета индивидуальных доз облучения граждан РФ (ЕСКИД) за 2014 г. Анализ выполнен на основе ежегодных сведений, содержащихся в формах федерального государственного статистического наблюдения № 1-ДОЗ, № 2-ДОЗ, № 3-ДОЗ и № 4-ДОЗ и представленных организациями и территориями, подотчетными Роспотребнадзору.По данным формы № 1-ДОЗ, общее число организаций, представивших сведения по дозам облучения персонала в 2014 г., составляло 16 424, а численность персонала – 130 688 человек. Средняя доза облучения персонала группы А составила 1,13 мЗв/год. Коллективная доза облучения персонала составила 132,5 чел.-Зв/год.По данным формы № 3-ДОЗ, в Российской Федерации в 2014 г. проведено 261 млн рентгено-диагностических процедур. Средняя доза медицинского облучения в расчете на одного жителя составила 0,46 мЗв/год, а коллективная доза – 66883,4 чел.-Зв/год. Наибольший вклад в коллективную дозу (40,3%) вносит компьютерная томография.Средняя по Российской Федерации годовая эффективная доза облучения населения за счет природных источников ионизирующего излучения по данным форм статистической отчетности № 4-ДОЗ за 2014 г. составила 3,48 мЗв/год. В структуре годовой эффективной дозы облучения населения природными источниками ионизирующего излучения около 59% приходится на облучения за счет изотопов радона и их дочерних продуктов. В 2014 г. были представлены данные о дозах производственного облучения 5651 работника 50 предприятий, расположенных на территории 18 регионов России. Значения доз производственного облучения работников этих предприятий находятся в диапазоне от 0,01 до 3,42 мЗв/год.В статье даны Приложения с итоговыми обобщенными формами ЕСКИД по формам статистического наблюдения № 1,3 и 4-ДОЗ

The method of formation of skills of simulation modeling the it professional

Purpose of the study. The aim is to create a technique targeted at the development of simulation skills in higher education environment, where students are competent in applying information technologies in economics. The relevance of the research lies in the fact that the existing methodological developments often focus on a specific software tool or methodology that cannot respond to all economic problems. A specialist in simulation modeling should possess integrative interdisciplinary knowledge from related scientific fields, for example, probability theory and mathematical statistics, higher mathematics, be familiar with other methods of solving economic problems: linear, nonlinear, dynamic programming, optimization; show proficiency in structural and functional analysis; be able to explore complex processes and systems comprehensively.Materials and methods. The following pedagogical approaches and teaching methods were implemented in this research: ● a systematic approach to solving complex problems based on the modelling economic objects as systems operating in a certain environment, ● activity approach to develop students’ professional competences in the process of creation, debugging and optimization of computer models of economic systems; ● problem teaching method in the framework of research and analysis of educational problems of the subject area; ● implemented interactive teaching methods; ● multimedia methods in the content of teaching materials of the discipline, including electronic manuals, educational videos, as well as multimedia presentations. The research also utilized information technologies, in which computers, communication equipment and software environments are: ● means to provide educational material to students for the transfer of knowledge; ● tools for designing, developing and conducting simulation experiments. In addition, we used the following special professional technologies, methods and tools in the process of teaching students: ● structural and functional modeling methodology; ● discrete-event approach to simulation methodology; ● special software for development and research of simulation models of economic processes and systems: Arena 15.0, AnyLogic 8.3.2. According to the requirements of the new educational standards, the student must master a sufficiently large amount of general cultural, professional and specialized competencies included in the curriculum. The application of the proposed approaches and methods allows to provide effective development of skills of simulation modeling of educational programs for bachelors of «Applied Informatics» and «Business Informatics».Results. The study created a method of teaching students the skills of simulation modeling. The research also established the model of formation of readiness of the IT specialist to the development of simulation models of economic processes and systems in higher school. We also identified important methodological conditions for the formation of professional competencies of students in the field of modeling, such as: ● application of a systematic approach to the analysis of domain problems, as well as for the synthesis of mathematical simulation models of business processes and economic systems; ● practical orientation of the content of training (selection and research in the educational process of the most characteristic, typical problems of the economy); ● integration of interdisciplinary knowledge, methods and approaches to solve complex problems.Conclusion. The method can equip students with skills of simulation modeling with various areas of practical application. First, this technique can be used by university students who are engaged in pursuing practical skills and basic system knowledge in the field of simulation. Secondly, teachers can use it, conducting courses: “Computer modeling”, “Mathematical and simulation modeling”, “Modeling of processes and systems” in the educational process of the University to improve the professional competence of students training simulation modeling. Third, the outcomes may be of interest to managers of educational programs in the areas of: “Applied Informatics”, “Business Informatics”, etc. to improve the structure and sequence of disciplines of competence-oriented curricula. Finally, the application of the proposed methodology in the educational process of the University will enhance professional expertise of young specialists and undoubtedly address the needs of potential employers

ENVIRONMENTAL HAZARDS AND LABOUR PROTECTION IN AGRICULTURE WITH THE ORGANIC FARMING DEVELOPMENT: A MODEL OF INTEGRATED ASSESSMENT

The aim of the research is the assessment of environmental hazards and occupational safety to implement the most effective ways to protect workers, the environment from the effects of hazardous and harmful factors when using chemicals in agriculture.Research methods: monographic, abstract‐logical, mathematical and logical‐linguistic modeling, computational‐ constructive, probability theory, expert estimates, etc.Results: a model of integrated assessment of environmental hazards and labor protection in agriculture, including nine assessment blocks: 1) soil contamination by pesticides, agrochemicals and heavy metals; 2) the balance of nitrogen, phosphorus and potassium, ensuring environmental protection; 3) the load of livestock on pastures; 4) the ratio of stabilizing and destabilizing factors; 5) the risk of waste and by‐products; 6) the production of environmentally safe products; 7) working conditions in the workplace; 8) the level of investment in labor protection, environment and environmentally safe products; 9) the level of environmental culture and culture of labor protection of workers and the population.Conclusion: the Model is tested in the working conditions of LLC  ʺMalinischiʺ of the Pronsky district of the Ryazan region in manual mode and can be the basis for the implementation of information and computer technology assessment

Epidemiological Situation of Crimean-Congo Hemorrhagic Fever (CCHF) in the South of Russia in 2010 and Prognosis for the Year of 2011

Presented are the data on Crimean hemorrhagic fever epidemiological situation and morbidity in the South and North-Caucasian Federal Districts of the Russian Federation in 2010. Epizootic situation in the Stavropol region has been analyzed. The prognosis as regards CHF for the year of 2011 in the territory of the South and North-Caucasian Federal Districts is presented, based on epizootiological monitoring