Response to Invasion by Antigen and Effects of Threshold in an Immune Network Dynamical System Model with a Small Number of Degrees of Freedom

We study a dynamical system model of an idiotypic immune network with a small number of degrees of freedom, mainly focusing on the effect of a threshold above which antibodies can recognise antibodies. The response of the system to invasions by antigens is investigated in the both models with and without the threshold and it turns out that the system changes in a desirable direction for moderate magnitude of perturbation. direction for moderate magnitude of perturbation. Also, the propagation of disturbance by an antigen is investigated in the system of one-dimensionally connected basic units taking the closed 3-clone system as a unit, and it is clarified that the threshold of the system has effects to enhance the stability of the network and to localise the immune response.Comment: 6 pages, 6 figures. Submitted to Prog. Theor. Phy

Characterization of the noble gases and CRE age of the D'Orbigny angrite

Introduction: The D’Orbigny angrite, a 16.55 kg stone, was found 1979 in Argentina [1]. Mineralogy and chemistry of this meteorite were characterized in detail [2-6]. A Pb-U-Th age of 4.559 Ga was obtained for pyroxenes by Jagoutz et al. [7]. Here we report results on the noble gas isotopic composition and, in particular, on the cosmic-ray exposure (CRE) age of D’Orbigny

A new clinical tool for assessing numerical abilities in neurological diseases: numerical activities of daily living

The aim of this study was to build an instrument, the numerical activities of daily living (NADL), designed to identify the specific impairments in numerical functions that may cause problems in everyday life. These impairments go beyond what can be inferred from the available scales evaluating activities of daily living in general, and are not adequately captured by measures of the general deterioration of cognitive functions as assessed by standard clinical instruments like the MMSE and MoCA. We assessed a control group (n = 148) and a patient group affected by a wide variety of neurological conditions (n = 175), with NADL along with IADL, MMSE, and MoCA. The NADL battery was found to have satisfactory construct validity and reliability, across a wide age range. This enabled us to calculate appropriate criteria for impairment that took into account age and education. It was found that neurological patients tended to overestimate their abilities as compared to the judgment made by their caregivers, assessed with objective tests of numerical abilities

Fraction of clear skies above astronomical sites: a new analysis from the GOES12 satellite

Comparing the number of clear nights (cloud free) available for astronomical observations is a critical task because it should be based on homogeneous methodologies. Current data are mainly based on different judgements based on observer logbooks or on different instruments. In this paper we present a new homogeneous methodology on very different astronomical sites for modern optical astronomy, in order to quantify the available night time fraction. The data are extracted from night time GOES12 satellite infrared images and compared with ground based conditions when available. In this analysis we introduce a wider average matrix and 3-Bands correlation in order to reduce the noise and to distinguish between clear and stable nights. Temporal data are used for the classification. In the time interval 2007-2008 we found that the percentage of the satellite clear nights is 88% at Paranal, 76% at La Silla, 72.5% at La Palma, 59% at Mt. Graham and 86.5% at Tolonchar. The correlation analysis of the three GOES12 infrared bands B3, B4 and B6 indicates that the fraction of the stable nights is lower by 2% to 20% depending on the site